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The Skadar/Shkodra Lake Environment
This book reviews the unique ecosystem of the Lake Skadar/Shkodra and its basin, and discusses the latest advances made in this region to face the impact of climate change. Divided into 23 chapters, the book gathers leading expertise from various scientific and engineering communities and provides readers with extensive discussions of core issues, including the water and sediment chemistry of Lake Skadar/Shkodra and the metal pollution that is evident in plants, aquatic invertebrates and fish. Readers will discover how a sustainable science-based management approach can be applied to the Lake Skadar/Shkodra region, and will learn about the environment prospects for the region. This book is intended as an essential tool for all scientists interested in the Lake Skadar/Shkodra environment – in particular those investigating the interactions between land and water, between limnology and biota, and between natural and cultural resources.
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Respiratory Support: Clinical Applications and the Novel Future
Respiratory support is a series of significant techniques used widely in clinical which saves a great number of patients with impaired pulmonary function and respiratory failure caused by pneumonia, sepsis, trauma, and acute exacerbation of chronic obstructive pulmonary disease, especially in recent years of Covid-19. It could improve oxygenation, reduce respiratory rate, and maintain normal ventilation. These techniques include oxygen therapy, high-flow nasal cannula, noninvasive ventilation, mechanical ventilation, and extracorporeal membrane oxygenation et al. Respiratory support has been improved increasingly these 20 years. Summarizing experience from past cases and keeping up with the latest technology is crucial to improve patient management and prognosis.
Genetic Polymorphism and Disease
Genetic polymorphisms are important determinants of phenotypic variations and may modulate the risk to or even cause various diseases including genetic disorders and multifactorial diseases. Genetic polymorphisms also serve as important genetic, population and evolutionary markers that allow the study of genetic and evolutionary aspects of individuals, populations and organisms and aid in tracing the evolutionary and parental lineages. Genetic polymorphisms in low penetrance genes are responsible for the alterations in the gene expression of critical signal transduction proteins and metabolic enzymes. Some of these polymorphisms are linked to increased susceptibility to various diseases espe...
Drug Discovery for Schizophrenia
Since the pioneering pharmacotherapy for treatment of schizophrenia in the 1950s by antipsychotics, only a few major innovations have been made, pointing to a general stagnation in the field of pharmacology of schizophrenia. Drug Discovery for Schizophrenia covers new insights in the field of schizophrenia with an aim to advance the understanding of scientists and clinicians in this area and to fuel drug discovery. The book outlines a change in the way schizophrenia is treated by moving away from focusing only on treating symptoms in patients. Innovative drugs emerge from deeper comprehension of the pathological processes that emerge earlier in life, hence, providing strategies for preventative therapy to alter the course of this mental disorder. Amongst other current topics, the book covers new findings in genetics and epigenetics, progress in animal models for schizophrenia and the usage of induced pluripotent stem cells. The combination of these important areas benefit psychiatric neuroscience, filling the gaps in the knowledge of neurobiology of schizophrenia and providing novel perspectives for future drug development.
Central Functions of the Ghrelin Receptor
The Ghrelin receptor was identified before its natural ligand ghrelin. This receptor is found both centrally and peripherally, and has been shown to affect various processes, such as food intake, gut motility, memory, glucose and lipid metabolism, cardiovascular performances, reproduction, memory, and immunological responses, amongst others. The functions of the ghrelin receptor in the central nervous system are numerous and are still being explored. In this book we specifically focus on the various roles of the ghrelin receptor in the central nervous system. In a first set of chapters, the book will focus on the discovery and the properties of this intriguing constitutively active G-protein...
Nanocarriers in Neurodegenerative Disorders
Due to the lack of secure, efficient, and patient-friendly therapies for neurodegenerative disorders, there is a rising demand for innovative approaches. Despite the limited number of nanocarriers approved for human use, they have demonstrated significant potential in preclinical and, in some instances, clinical trials. In alignment with this objective, the chapters of the book are structured to offer a comprehensive overview of recent advancements in medication and dosage form development, specifically emphasizing the nanoparticulate system for targeting the brain. This book aims to furnish readers with a thorough understanding of the clinical application of nanocarrier systems for treating...
Electron Kinetics and Applications of Glow Discharges
This book resulted from the NATO Advanced Research Workshop on “Electron Kinetics and Applications of Glow Discharges,” held in St. Petersburg, Russia, on May 19-23, 1997. Glow discharges have found widespread applications in many technological processes from the manufacture of semiconductors, to recent developments in na- technology, to the traditional fields of gas lasers, and discharge lamps. Consequently, the interest in the physics of glow discharges has experienced yet another resurgence of interest. While the non-equilibrium character of glow discharges is widely accepted, the opinion still prevails that the main features can be captured by fluid models, and that kinetic treatments are only required for the understanding of subtle details. The erroneousness of this belief is demonstrated by the failure of fluid models to describe many basic features of glow discharges such as, for instance, electrode phenomena, striations, and collisionless heating effects. An adequate description of glow discharges thus has to be of kinetic nature.
Bioactive Peptides
Bioactive peptides are used to enhance the body's antioxidant status, antisepsis capacity, immune function, anti-inflammatory capacity, mineral absorption, and appetite. They can also mitigate major metabolic derangements arising from chronic illnesses which result in unwanted weight loss. Presenting data from human studies, clinical trials, and recent research findings, this work summarizes the applications and benefits of this therapy. The book covers host response, quality factors, protein economics, and muscle loss. It includes case studies on aging, AIDS, COPD, diabetes, inflammatory bowel disease, kidney failure, and tuberculosis.
Bipolar Disorders: New Insights for the Healthcare Professional: 2011 Edition
Bipolar Disorders: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Bipolar Disorders. The editors have built Bipolar Disorders: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Bipolar Disorders in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Bipolar Disorders: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
