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Multimorbidity in Primary Care
Multimorbidity is the term used when an individual has two or more long term health conditions and is considered a major health care challenge facing countries globally. The prevalence of Multimorbidity is increasing, partly due to an aging population, and is associated with a reduced quality of life and life expectancy, as well as an increased use of emergency or unplanned care.
In Sickness and In Health
Despite significant improvements in many health outcomes over the past 60 years, many chronic problems in Indonesia’s health system including financial sustainability, governance and inequities in accessing health care have long been apparent, even before the COVID-19 pandemic. The epidemiological transition associated with demographic and socioeconomic change in recent decades makes Indonesia one of many countries that still struggle to address the issues of communicable, maternal and nutritional diseases while facing an increasing burden of non-communicable diseases. The contributors to In Sickness and In Health: Diagnosing Indonesia investigate challenges and opportunities facing the In...
Molecular Diagnostics in Cancer Patients
This book aims to bring together a broad variety of examples of the role of pharmacogenomics in current drug development, uncovering dynamic concentration-dependent drug responses on biological systems to understand pharmacodynamics responses in human cancer where genetic lesions serve as tumor markers and provide a basis for cancer diagnosis. The book describes methods and protocols applied in molecular diagnostics. It offers pathologists and researchers providing molecular diagnostic services an array of the most recent and readily accessible reference to compare methods and techniques. Highlights include the molecular diagnosis of genetic aberrations by quantitative polymerase reaction (q...
Extracellular Vesicles
Extracellular vesicles (EVs) are nanoscale vesicles secreted by cells that mediate horizontal cargo transport from donor to recipient cell, thereby establishing cell-cell communication and signaling. This book provides critical information on the fundamentals of EVs, their roles in diseases like cancer, and their use in disease management. The chapters emphasize the emerging data confirming the role of EVs in the pathogenesis of diseases and discuss the scientific advances that have made it feasible to characterize and engineer EVs, leading to their use as tools in biomarker discovery and disease diagnosis, prognosis, therapeutic application, and theranostics. This volume is a valuable resource for basic biologists, translational scientists, and clinicians.
Computational Biology for Stem Cell Research
Computational Biology for Stem Cell Research is an invaluable guide for researchers as they explore HSCs and MSCs in computational biology. With the growing advancement of technology in the field of biomedical sciences, computational approaches have reduced the financial and experimental burden of the experimental process. In the shortest span, it has established itself as an integral component of any biological research activity. HSC informatics (in silico) techniques such as machine learning, genome network analysis, data mining, complex genome structures, docking, system biology, mathematical modeling, programming (R, Python, Perl, etc.) help to analyze, visualize, network constructions, ...
Bioaerosols Emission from Anthropogenic Sources
Bioaerosols Emission from Anthropogenic Sources: Influencing Factors, Microbial Diversity, Epidemiological Threats, and Control Approaches covers various sources of biohazards and their associated risk factors. These air contaminants are developing concerns to people and the environment and must be addressed to avert future dangers. As little is known about their precise sources, controlling variables, microbial diversity, the involvement of co-pollutants, and dispersion and control methods, this book will assist stakeholders, including the public, government officials, and policymakers in developing successful strategies for ensuring society's safety. - Identifies potential emission stages at different anthropogenic sources of bioaerosols - Discusses characteristics, fate and development of effective control strategies for minimizing exposure to site specific bioaerosols - Presents cleaner production and sustainable development tactics of bioaerosols
Nanotechnology for Infectious Diseases
This book aims to cover the applications of nanotechnology against human infectious diseases. The chapters of the book discuss the role of nanotechnology in the efficient diagnosis and treatment of these diseases. It explicitly provides an overview of nanodiagnostics for infectious diseases from nanoparticles-based, nanodevice-based, and point-of-care platforms. The book also covers the state-of-the-art review of recent progress in biomimetic and bioengineered nanotherapies to treat infectious diseases. It also presents a nano carrier-based CRISPR/Cas9 delivery system for gene editing and its applications for developing interventional approaches against communicable diseases. Further, it reviews the recent developments in nanotechnology to engineer nanoparticles with desired physicochemical properties as a line of defense against multi-drug resistance micro-organisms. Cutting across the disciplines, this book serves as a guide for researchers in biotechnology, parasitology, and nanotechnology.
