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Developments in T Cell Based Cancer Immunotherapies
This volume illustrates the salient aspects of cancer biology relevant to the successful implementation of immunotherapy. Topics include enhancement of antigen-specific immune responses by anti-cancer vaccines, modulation of the function of T cells within the tumor microenvironment, and the effects of genetic, epigenetic, developmental, and environmental determinants on T cell function. Other topics covered include the ex vivo expansion of T or other immune cells and their genetic modification or reprogramming to increase their ability to survive and expand when adoptively transferred back to the patients. Specific attention is devoted to the genetic manipulation of T cells through the introduction of re-directed T cell receptors, chimeric antibody receptors, and other genetic manipulation aimed at improving their effectiveness as anti-cancer agents. Furthermore, the revolutionary role of checkpoint inhibitors and their potential in combination with other immunotherapeutic approaches or with standard chemo and radiation therapy are extensively discussed.
The J. Paul Getty Museum Journal
The J. Paul Getty Museum Journal 17 is a compendium of articles and notes pertaining to the Museum's permanent collections of antiquities, decorative arts, drawings, and photographs. This volume includes a supplement introduced by John Walsh with a fully illustrated checklist of the Getty’s recent acquisitions. Volume 17 includes articles written by Elisabeth Doumeyrou, Gerhard Gruitrooy, Lee Hendrix, Clark Hulse, David Jaffé, Jean-Nérée Ronfort, and Belinda Rathbone.
Labyrinth
Labyrinth: The Ultimate Visual History is the definitive thirtieth-anniversary exploration of the beloved Jim Henson classic, featuring rare artwork, interviews, and on-set photos. Journey back to Jim Henson's Labyrinth in this visually stunning celebration of the enchanting fantasy classic. Three decades after its release, Labyrinth, starring David Bowie and Jennifer Connelly, continues to enthrall audiences with its winning mixture of fairy-tale magic, fantastical creatures, and unforgettable music. Filled with a wealth of rare and unseen behind-the-scenes imagery, this book explores the creation of the film as seen through the eyes of the artists, costume designers, and creature creators ...
Billboard
In its 114th year, Billboard remains the world's premier weekly music publication and a diverse digital, events, brand, content and data licensing platform. Billboard publishes the most trusted charts and offers unrivaled reporting about the latest music, video, gaming, media, digital and mobile entertainment issues and trends.
Mimi
It's Christmas Eve in Manhattan. Harrison Hanafan, noted plastic surgeon, falls on his ass. So far, so good. 'Ya can't sit there all day, buddy, looking up people's skirts!' chides a weird gal in a coat like a duvet - Mimi! She kindly conjures for him the miracle of a taxi. Recuperating in his apartment with Schubert, Bette Davis, and a foundling cat, Harrison adds items to his life's work, a List of Melancholy Things (Walmart, puppetry, Velcro, whale eyes, shrimp-eating contests...). But when he receives a dreaded invitation to address his old school, Mimi reappears, with all her curves and chaos. She and Harrison fall emphatically in love. And, as their love-making reaches a whole new kind of climax, the sweet smell of revolution is in the air.
How to Solve Crosswords: a Handbook
This handbook is the result of the authors experience in solving crosswords (almost exclusively from the New York Times) for a period of over 10 years and is designed to help puzzle solvers of all abilities. It covers such strategic subjects as themes in puzzles and what a clue is attempting to elicit, as well as such tactical subjects as what, precisely, is to be written in the squares in a puzzle. Thus, the scope of the handbook ranges from the general to the detailed. Some of the subjects covered are foreign languages (French is the most popular, by far), mythology, the Old Testament, literature (including poetry and drama), classical music, sports (baseball is the crossword favorite), en...
Astro Admirers: The Elemodal Matchmaking System
Astro Admirers What makes two people compatible? Astro Admirers introduces the ""Elemodal"" Matchmaking System which is based on the elements and modes in Astrology. The system uses the three most important signs in Astrology - the Sun sign, the Moon sign and the sign on the Ascendant - to determine a person's personality type. There are 102 personality types in the ""Elemodal"" system ranging from the most outgoing personalities to the most retiring, the most inflexible personalities to the most adaptable. Matchmaking is calculated using a combination of both similarity and complementary criteria to create balance in a relationship. Over 1400 well known people are listed within the personality types. The author is a graduate of Lancaster University, England. She has been married for 27 years and has three children.
Quentin Tarantino
A fascinating collection of interviews with the colorful and provocative director of Reservoir Dogs, Kill Bill, Pulp Fiction, Django Unchained, and many other films
Roger Ebert's Movie Yearbook 2004
Featuring every review Ebert wrote from January 2001 to mid-June 2003, this treasury also includes his essays, interviews, film festival reports, and In Memoriams, along with his famous star ratings.
