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Developmental Plasticity of Inhibitory Circuitry
Neuroscience has long been focused on understanding neural plasticity in both development and adulthood. Experimental work in this area has focused almost entirely on plasticity at excitatory synapses. A growing body of evidence suggests that plasticity at inhibitory GABAergic and glycinergic synapses is of critical importance during both development and aging. The book brings together the work of researchers investigating inhibitory plasticity at many levels of analysis and in several different preparations. This topic is of wide relevance across a number of different areas of research in neuroscience and neurology. Medical problems such as epilepsy, mental illness, drug abuse, and movement disorders can result from malfunctioning inhibitory circuits. Further, the maturation of inhibitory circuits may trigger the onset of critical periods of neural circuit plasticity, raising the possibility that such plastici periods could be reactivated for medical benefit by manipulating inhibitory circuitry.
Developmental Plasticity of Inhibitory Circuitry
Neuroscience has long been focused on understanding neural plasticity in both development and adulthood. Experimental work in this area has focused almost entirely on plasticity at excitatory synapses. A growing body of evidence suggests that plasticity at inhibitory GABAergic and glycinergic synapses is of critical importance during both development and aging. The book brings together the work of researchers investigating inhibitory plasticity at many levels of analysis and in several different preparations. This topic is of wide relevance across a number of different areas of research in neuroscience and neurology. Medical problems such as epilepsy, mental illness, drug abuse, and movement disorders can result from malfunctioning inhibitory circuits. Further, the maturation of inhibitory circuits may trigger the onset of critical periods of neural circuit plasticity, raising the possibility that such plastici periods could be reactivated for medical benefit by manipulating inhibitory circuitry.
From Ecology to Brain Development: Bridging Separate Evolutionary Paradigms
The nervous system is the product of biological evolution and is shaped by the interplay between extrinsic factors determining the ecology of animals, and by intrinsic processes that dictate the developmental rules that give rise to adult functional structures. This special topic is oriented to develop an integrative view from behavior and ecology to neurodevelopmental processes. We address questions such as how do sensory systems evolve according to ecological conditions? How do neural networks organize to generate adaptive behavior? How does cognition and brain connectivity evolve? What are the developmental mechanisms that give rise to functional adaptation? Accordingly, the book is divid...
Development and Plasticity in Sensory Thalamus and Cortex
This volume provides an update on the multitude of technical and experimental approaches in understanding the development and plasticity of the mammalian sensory thalamus and neocortex. The focus is on visual and somatosensory thalamus and neocortex in rodents and carnivores, and functional imaging studies in developing and aging human neocortex. It further provides a synthetic theoretical framework for future studies.
Cortical Areas
The study of areas in the cerebral cortex has a long history, bringing empirical data into close relation with fundamental conceptual issues about the cortex. The subject is currently being revitalized with the advent of new experimental methods and this book brings a modern perspective to the study of these areas. Cortical Areas: Unity and Diversi
Neural Systems: Analysis and Modeling
In recent years there has been tremendous activity in computational neuroscience resulting from two parallel developments. On the one hand, our knowledge of real nervous systems has increased dramatically over the years; on the other, there is now enough computing power available to perform realistic simulations of actual neural circuits. This is leading to a revolution in quantitative neuroscience, which is attracting a growing number of scientists from non-biological disciplines. These scientists bring with them expertise in signal processing, information theory, and dynamical systems theory that has helped transform our ways of approaching neural systems. New developments in experimental ...
The New Handbook of Multisensory Processing
The major reference work for a rapidly advancing field synthesizes central themes, reports on current findings, and offers a blueprint for future research. Scientists' attempts to understand the physiology underlying our apprehension of the physical world was long dominated by a focus on the individual senses. The 1980s saw the beginning of systematic efforts to examine interactions among different sensory modalities at the level of the single neuron. And by the end of the 1990s, a recognizable and multidisciplinary field of "multisensory processes" had emerged. More recently, studies involving both human and nonhuman subjects have focused on relationships among multisensory neuronal ensembl...
Spontaneous Activity in the Sensory System
Spontaneous activity in the nervous system is defined as neural activity that is not driven by an external stimulus and is considered a problem for sensory processing and computation. However, spontaneous activity is not completely random and often has unique spatiotemporal patterns that instruct neural circuit development in the developing brain. Moreover, normal and aberrant patterns of spontaneous activity underlie behavioral states and diseased conditions in the adult brain. The recent technological development has shed light on these unique questions in spontaneous activity. This eBook provides both original and review articles in the propensity, mechanisms, and functions of spontaneous activity in the sensory system. Our goal is to define the state of knowledge in the field, the current challenges, and the future directions for research.
The Auditory Cortex
There has been substantial progress in understanding the contributions of the auditory forebrain to hearing, sound localization, communication, emotive behavior, and cognition. The Auditory Cortex covers the latest knowledge about the auditory forebrain, including the auditory cortex as well as the medial geniculate body in the thalamus. This book will cover all important aspects of the auditory forebrain organization and function, integrating the auditory thalamus and cortex into a smooth, coherent whole. Volume One covers basic auditory neuroscience. It complements The Auditory Cortex, Volume 2: Integrative Neuroscience, which takes a more applied/clinical perspective.
