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DNA methylation is essential for the normal development and functioning of organisms. This volume discusses the latest developments in this very active field of research. It presents the evolution of DNA methylation, mammalian DNA methyltransferases, DNA methylation and demethlyation, DNA methylation and silencing and the role it plays in medicine including cancer. Discusses new discoveries, approaches, and ideas Contributions from leading scholars and industry experts Reference guide for researchers involved in molecular biology and related fields
Amebiasis, a parasitic disease transmitted by the unicellular protozoan parasite Entamoeba histolytica, is the cause of at least 100,000 deaths each year. The disease is mostly prevalent in developing countries and is one of the three common causes of death from parasitic diseases. The parasite has two stages in its life cycle in the host: the infective cyst and the invasive trophozoite. In the large intestine, the parasite feeds on bacteria and on cellular debris. No vaccine against amebiasis currently exists. Although metronidazole is the drug of choice for treating amebiasis, adverse effects in patients and potential resistance to metronidazole in other protozoa exist. About nine out of 1...
This book documents and presents new developments in the study of amebiasis, one of the neglected tropical diseases. Nearly 50 million people worldwide are infected with the pathogen Entamoeba histolytica, causing large-scale morbidity and mortality particularly in developing countries. This book will help clinicians for better diagnosis and management of the disease, researchers for initiating research projects on some of the poorly understood aspects of the disease and the pathogen, and students for updating their knowledge. The subjects covered range from genomics and molecular and cell biology to drug resistance and new drug development, highlighting major advances in recent years in our...
"This collection of new essays offers groundbreaking perspectives on the ways that food and foodways serve as an element of decolonization in Mexican-origin communities. The writers here take us from multigenerational acequia farmers, who trace their ancestry to Indigenous families in place well before the Oñate Entrada of 1598, to tomorrow's transborder travelers who will be negotiating entry into the United States. Throughout, we witness the shifting mosaic of Mexican-origin foods and foodways from Chiapas to Alaska. Global food systems are also considered from a critical agroecological perspective, which takes into account the ways colonialism affects native biocultural diversity, ecosystem resilience, and equality across species and generations. Mexican-Origin Foods, Foodways, and Social Movements is a major contribution to the understanding of the ways that Mexican-origin peoples have resisted and transformed food systems through daily lived acts of producing and sharing food, knowledge, and seeds in both place-based and displaced communities. It will animate scholarship on global food studies for years to come."--Page [4] of cover.
This study deepens our historical understanding of the North-African Jewish and Middle Eastern Jewish experience during WWII, which is often under- or mis-represented by the media in Israel, the Arab world, France, and Italy. Public, historical and sociocultural discourse is examined to clarify whether these communities are accepted by the world as "Holocaust survivors". Further, it determines the extent to which their wartime history is revealed to Israeli society in its cultural performances. Importantly, this work addresses the reasons why the Holocaust of North African Jewry is absent from Israeli and world consciousness. Finally, the study contemplates the consequences of these phenomen...
Multiple demographic or economic parameters contribute to the origin of emerging infections, for example: poverty, urbanization, climate change, conflicts and population migrations. All these factors are a challenge to assess the impact (present and future) of parasitic diseases on public health. The intestine is a major target of these infections; it is a nutrient-rich environment harbouring a complex and dynamic population of 100 trillion microbes: the microbiome. Most researches on the microbiome focus on bacteria, which share the gut ecosystem with a population of uni- and multi cellular eukaryotic organisms that may prey on them. Our interest focuses on the families of eukaryotic microb...
A comprehensive, in-depth study of Arab documentary filmmaking by leading experts in the field While many of the Arab documentary films that emerged after the digital turn in the 1990s have been the subject of close scholarly and media attention, far less well studied is the immense wealth of Arab documentaries produced during the celluloid era. These ranged from newsreels to information, propaganda, and educational films, travelogues, as well as more radical, artistic formats, such as direct cinema and film essays. This book sets out to examine the long history of Arab nonfiction filmmaking in the Middle East and North Africa across a range of national trajectories and documentary styles, f...
In Identity, Place, and Subversion in Contemporary Mizrahi Cinema in Israel , Yaron Shemer presents the most comprehensive and systematic study to date of Mizrahi (Oriental-Jewish or Arab-Jewish) films produced in Israel in the last several decades. Through an analysis of dozens of films the book illustrates how narratives, characters, and space have been employed to give expression to Mizrahi ethnic identity and to situate the Mizrahi within the broader context of the Israeli societal fabric. The struggle over identity and the effort to redraw ethnic boundaries have taken place against the backdrop of a long-standing Zionist view of the Mizrahi as an inferior other whose “Levantine” cul...
The human body is constantly faced with microorganisms. Most of these bacteria, fungi, and viruses are harmless, many of them are beneficial, and a small fraction is pathogenic. For humans, infection with pathogenic microorganisms can be very serious or even fatal, ranging from mild transient or chronic infections to death. The first line of defence against pathogens is our innate immune system. Beside chemical and physical defence mechanisms of the innate immune system, phagocytic cells such as macrophages play a crucial role in the fight against pathogenic microorganisms. However, phagocytic cells and pathogens are in a constant evolutionary arms race, inventing new strategies to successfu...