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This three-volume set of LNCS 14086, LNCS 14087 and LNCS 14088 constitutes - in conjunction with the double-volume set LNAI 14089-14090- the refereed proceedings of the 19th International Conference on Intelligent Computing, ICIC 2023, held in Zhengzhou, China, in August 2023. The 337 full papers of the three proceedings volumes were carefully reviewed and selected from 828 submissions. This year, the conference concentrated mainly on the theories and methodologies as well as the emerging applications of intelligent computing. Its aim was to unify the picture of contemporary intelligent computing techniques as an integral concept that highlights the trends in advanced computational intelligence and bridges theoretical research with applications. Therefore, the theme for this conference was "Advanced Intelligent Computing Technology and Applications". Papers that focused on this theme were solicited, addressing theories, methodologies, and applications in science and technology.
Cancer immunotherapy, including immune checkpoint inhibitors (ICIs) and chimeric antigen receptor T-cell (CAR-T) therapy, has revolutionized the paradigm in cancer treatment. However, the clinical outcome of immunotherapy varies considerably among patients and only a minority of patients achieve long-term clinical benefits. This is largely attributed to the fact that existing cancer immunotherapies, which concentrate on several classical targets (CTAL-4, PD-1/PD-L1, etc.) and limited types of immune cell populations (T cells), are insufficient to cope with the complexity of highly heterogeneous tumor microenvironment (TME). This calls for more efforts to not only expand our toolbox for manip...
Fuzzy logic is vital to applications in the electrical, industrial, chemical and engineering realms, as well as in areas of management and environmental issues. Data mining is indispensible in dealing with big data, massive data, and scalable, parallel and distributed algorithms. This book presents papers from FSDM 2022, the 8th International Conference on Fuzzy Systems and Data Mining. The conference, originally scheduled to take place in Xiamen, China, was held fully online from 4 to 7 November 2022, due to ongoing restrictions connected with the COVID-19 pandemic. This year, FSDM received 196 submissions, of which 47 papers were ultimately selected for presentation and publication after a...