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Conducting patient interviews within a clinical trial setting
Qualitative data centered on patients’ experiences and perspectives typically go uncollected in clinical trial settings. Yet patients’ treatment experiences offer complementary insights and context on topics such as disease management, treatment gaps, and previous treatments outside of those gathered in traditional patient-reported outcome questionnaires. Qualitative interviews can capture patients’ perceptions of treatment needs, more fully explore meaningful changes experienced as a result of treatment, and reveal outcomes that are most important to patients. Asking patients detailed questions can provide insight into the “why” of a patient’s expressed thought or feeling. The inclusion of patient interviews within clinical trials is a relatively new and evolving field of research. This article delineates the types of data that may be collected during interviews with clinical trial participants and outlines two approaches to conducting qualitative research in the clinical trial setting, with a focus on maximizing the value of the resulting data.
Biopharmaceutical Applied Statistics Symposium
This BASS book Series publishes selected high-quality papers reflecting recent advances in the design and biostatistical analysis of biopharmaceutical experiments – particularly biopharmaceutical clinical trials. The papers were selected from invited presentations at the Biopharmaceutical Applied Statistics Symposium (BASS), which was founded by the first Editor in 1994 and has since become the premier international conference in biopharmaceutical statistics. The primary aims of the BASS are: 1) to raise funding to support graduate students in biostatistics programs, and 2) to provide an opportunity for professionals engaged in pharmaceutical drug research and development to share insights...
Cognitive Interviewing
"As both an academic instructor in questionnaire design and a research design methodologist for the federal government, I feel this book is very timely, useful for students and practitioners, and unique in its use of real world practical examples that most everyone can relate." —Terry Richardson, General Accounting Office "The combination of theory and practical application will make this a useful book for students as well as professionals who want to learn how to incorporate cognitive interviewing into the questionnaire design process." —Rachel Caspar, RTI International The design and evaluation of questionnaires—and of other written and oral materials—is a challenging endeavor, fra...
STOP, THAT and One Hundred Other Sleep Scales
There are at least four reasons why a sleep clinician should be familiar with rating scales that evaluate different facets of sleep. First, the use of scales facilitates a quick and accurate assessment of a complex clinical problem. In three or four minutes (the time to review ten standard scales), a clinician can come to a broad understanding of the patient in question. For example, a selection of scales might indicate that an individual is sleepy but not fatigued; lacking alertness with no insomnia; presenting with no symptoms of narcolepsy or restless legs but showing clear features of apnea; exhibiting depression and a history of significant alcohol problems. This information can be used...
The MGH Review of Critical Care Medicine
The field of critical care medicine is evolving quickly. To prepare for certification and refresh their knowledge, today's practitioners need a concise multidisciplinary review that focuses on the core areas of critical care. Ideal for critical care fellows, critical care nurses, residents, and practitioners who spend time in the ICU. This book employs brief chapters on focused topics to help readers review core areas and test their knowledge. Features: Broad scope addresses all major topics is adult critical care with contributions from experts in a range of disciplines. Concise chapters based on commonly referenced topics make the review easy to navigate. Focused discussions are based on patient presentation and are structured to include common causes, initial management strategies, pathophysiology, differential diagnosis, management, and outcomes. Incisive review questions (3.10 per topic) include answers and explanations to help readers understand the "how" and "why" behind each answer. Staff of MGH and its sister institutions provide consistent terminology and presentation throughout the review.
Paediatric Endocrinology and Diabetes
This handbook covers anatomy and physiology before moving on to identification, investigation and management of specific endocrine disorders. As well as covering common and less common endocrine problems, there are also chapters on endocrine investigations and endocrine emergencies, designed for quick reference.
Peyronie's Disease
In this guidebook, international authorities review the current nonsurgical and surgical therapeutic options for dealing with Peyronie's disease. A variety of state-of-the-art research techniques is discussed. As the first medical text on the subject, this book provides an up-to-date summary of the etiology, natural history, and pathophysiology of this disease. Also discussed are the many misconceptions about Peyronie's disease.
Acne
Acne is one of the commonest skin diseases that primary care/family physicians and dermatologists have to treat. Confirming the diagnosis is rarely a problem and given the wide spectrum of treatment options there really is no reason why most patients with acne cannot be helped enormously. However, the vast number of therapeutic options now available can pose difficulties for the prescribing clinician in deciding which is the preferred treatment. The purpose of this book is to highlight several features of the disease including etiology and clinical presentation whilst also reviewing the treatments available along with their respective modes of action and potential adverse effects.
