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After Yona and her friends save the Fire Tribe from an invasion by the Kai Empire, word of their prowess spreads amongst those with deep faith in the Crimson Dragon King. Yona and the gang take cover at Saika Palace, but what trouble awaits when Su-won’s advisor Keishuk shows up to guard the Fire Tribe border? -- VIZ Media
Microglia are largely known as the major orchestrators of the brain inflammatory response. As such, they have been traditionally studied in various contexts of disease, where their activation has been assumed to induce a wide range of detrimental effects. In the last few years, a series of discoveries have challenged the current view of microglia, showing their active and positive contribution to normal brain function. This Research Topic reviewed the novel physiological roles of microglia in the developing, mature and aging brain, under non-pathological conditions. In particular, this Research Topic discussed the cellular and molecular mechanisms by which microglia contribute to the formati...
The mononuclear phagocyte system (MPS) comprises dendritic cells (DCs), monocytes and macrophages (MØs) that together play crucial roles in tissue immunity and homeostasis, but also contribute to a broad spectrum of pathologies. They are thus attractive therapeutic targets for immune therapy. However, the distinction between DCs, monocytes and MØ subpopulations has been a matter of controversy and the current nomenclature has been a confounding factor. DCs are remarkably heterogeneous and consist of multiple subsets traditionally defined by their expression of various surface markers. While markers are important to define various populations of the MPS, they do not specifically define the ...
A red-haired princess loses her family and her kingdom… Now she must rise and fight with her Dragon Warriors by her side! Princess Yona lives an ideal life as the only princess of her kingdom. Doted on by her father, the king, and protected by her faithful guard Hak, she cherishes the time spent with the man she loves, Su-won. But everything changes on her 16th birthday when tragedy strikes her family! While the Kingdom of Kohka and Sen Province armies battle, Hak goes all-out on the front lines and ends up fighting North Kai leader Ying Kuelbo one-on-one! Meanwhile, in a palace in Sen Province, will Yona be able to overcome Priest Gobi’s treachery?
When Su-won hears of Riri’s abduction, he launches surprise attacks on Sei fortresses in an attempt to save her. Meanwhile, Riri leaves Yona in a forest in order to lure Sei troops away from her. Will Riri escape capture and execution? -- VIZ Media
This volume focuses on the relevance of epigenetic mechanisms in autoimmune disease. It provides new directions for future research in autoimmune disease.
It can be seen that the insects are the still attracting most research and researchers. However, an increasing interest is emerging to study new invertebrate groups, especially those where the genome is known. Even though Drosophila has been and still is an excellent model for immune studies, it is now clear that there are great differences between immune responses in Drosophila and that of several other invertebrates, which indeed calls for more research on other invertebrates
The year 2010 marks the centennial for the identification of histamine and the first glimpse of its many physiological functions. From these initial findings a rich tapestry of research has uncovered roles for histamine in almost every physiological process with new findings emerging every year. These diverse roles of histamine have made for fertile ground for the discovery of novel therapeutics, and these drugs have been so successful that the term “antihistamine” has entered the common lexicon. This volume is an attempt to give a snapshot in time as to the current understanding of the role of histamine in just one important therapeutic area—inflammation. The first three chapters prov...
A red-haired princess loses her family and her kingdom… Now she must rise and fight for her throne! Princess Yona lives an ideal life as the only princess of her kingdom. Doted on by her father, the king, and protected by her faithful guard Hak, she cherishes the time spent with the man she loves, Su-won. But everything changes on her 16th birthday when tragedy strikes her family! Forbidden from contacting Hak and the Four Dragons, Yona sneaks out of her room at Hiryuu Palace! But when she comes face-to-face with Su-won, what words will she have for her father’s murderer? Later, Yona uncovers some past mysteries about Su-won’s parents!
Selected as a Doody's Core Title for 2022! Defining the field of immunology for 40 years, Paul’s Fundamental Immunology continues to provide detailed, authoritative, up-to-date information that uniquely bridges the gap between basic immunology and the disease process. The fully revised 8th edition maintains the excellence established by Dr. William E. Paul, who passed away in 2015, and is now under new editorial leadership of Drs. Martin F. Flajnik, Nevil J. Singh, and Steven M. Holland. It’s an ideal reference and gold standard text for graduate students, post-doctoral fellows, basic and clinical immunologists, microbiologists and infectious disease physicians, and any physician treating diseases in which immunologic mechanisms play a role.