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Visceral Pain
The chapters in this book are based on the Visceral Pain conference in Adelaide, Australia, under the auspices of the International Federation for Neurogastroenterology and Motility in 2021. This is one of the hottest fields of science and includes mechanisms involving how the microbiome communicates with the brain and how, when disordered, these mechanisms contribute to clinical diseases such as Irritable Bowel Syndrome and Inflammatory Bowel Disease. Researchers from around the globe presented their latest findings as a review of the current state of the art in the field from both the clinical and scientific points of view. These systems are now appreciated as being critical for shaping our well-being and their disorders underlie chronic clinical conditions of significant morbidity and mortality. The author team includes long-established authorities who significantly contributed to the advances in visceral pain research over the past two decades and the new generation that will continue to contribute to advancing our understanding of the field.
The Enteric Nervous System
Nearly 30 years ago, a number of scientists working on the Enteric Nervous System (ENS) gathered at Flinders University, in Adelaide, Australia to discuss the advances and future of their research. It was a friendly and stimulating meeting, attended by most of the major players, in what was to become the discipline of ‘Neurogastroenterology'. In 2014, the main Australasian Neuroscience Society meeting was held in Adelaide, Australia, providing the perfect opportunity to recreate a follow-up ENS meeting. As such, the ‘ENS II 2014 meeting’ aimed to identify how far the field of enteric neuroscience had developed, where the future was heading, and what technological advances had been made...
The Enteric Nervous System II
This book is based on the proceedings of the Enteric Nervous System conference in Adelaide, Australia, under the auspices of the International Federation for Neurogastroenterology and Motility. The book focuses on methodological strategies and unresolved issues in the field and explores where the future is heading and what technological advances have been made to address current and future questions. The Enteric Nervous System II continues in the tradition of a popular earlier volume which covered the previous meeting. Many of the same authors are contributing to this new volume, presenting state-of-the-art updates on the many developments in the field since the earlier meeting. The coverage include a wide range of topics, from structure and function of the enteric nervous system through gut motility and visceral pain. The author team includes long-established authorities who significantly contributed to the advances in ENS research over the past two decades and the new generation that will continue to contribute to advancing our understanding of the field.
Physiology of the Gastrointestinal Tract, Two Volume Set
Physiology of the Gastrointestinal Tract, Fifth Edition — winner of a 2013 Highly Commended BMA Medical Book Award for Internal Medicine — covers the study of the mechanical, physical, and biochemical functions of the GI Tract while linking the clinical disease or disorder, bridging the gap between clinical and laboratory medicine. The gastrointestinal system is responsible for the breakdown and absorption of various foods and liquids needed to sustain life. Other diseases and disorders treated by clinicians in this area include: food allergies, constipation, chronic liver disease and cirrhosis, gallstones, gastritis, GERD, hemorrhoids, IBS, lactose intolerance, pancreatic, appendicitis,...
LINACLOTIDE TREATMENT REDUCES ENDOMETRIOSIS-ASSOCIATED VAGINAL HYPERALGESIA AND MECHANICAL ALLODYNIA THROUGH VISCERO-VISCERAL CROSS-TALK
Background and aims: Endometriosis, an estrogen-dependent chronic inflammatory disease, is the most common cause of chronic pelvic pain (CPP). Here we investigated the effects of linaclotide, an FDA approved treatment for constipation-predominant IBS, in a rat model of endometriosis. Methods: Uterine horn tissue was transplanted into the mesentery of female Sprague-Dawley rats, and endometrial lesions developed eight weeks after surgery. Retrograde tracing was performed to label afferent neurons and central terminals of ileal, colonic and vaginal afferents. Guanylate cyclase-C (GC-C) mRNA expression was determined by quantitative RT-PCR and in situ hybridization.Results: Daily oral administr...
HEMORRHOIDS A Pain in the Rear No More
Hemorrhoids: A Pain in the Rear No More is an essential guide that delves into the complex world of hemorrhoidal disease, offering readers a thorough understanding of this common yet often misunderstood condition. The book begins with a clear definition and classification of hemorrhoids, distinguishing between internal and external types, and provides insight into their prevalence among different demographics. It explores the various causes of hemorrhoids, such as chronic constipation, straining during bowel movements, obesity, pregnancy, and a sedentary lifestyle, while also considering the impact of aging, dietary habits, and hereditary factors. In discussing the symptoms, the book covers ...
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Sleisenger and Fordtran's Gastrointestinal and Liver Disease E-Book
Now in its 10th edition, Sleisenger and Fordtran?s Gastrointestinal and Liver Disease remains your indispensable source for definitive, state-of-the-art answers on every aspect of gastroenterology and hepatology. Overcome your most complex clinical challenges and make optimal use of the newest techniques, technologies, and treatments?with superb guidance from hundreds of world-renowned authorities. Meticulous updates throughout include the latest approaches and improvements in gastrointestinal and liver disease diagnosis and therapy as well as hundreds of images and 35 new procedural videos. "..one of the most valuable clinical resources in the dynamic field of gastroenterology and hepatolog...
