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The construction of C-X (X = C, N, S) bonds is an important research content in the field of organic synthesis and drug preparation. Focusing on the green construction of the core skeleton of functional fine chemicals, the team has carried out research on green synthesis and catalytic reactions of fine chemicals, realized the effective synthesis of high value-added fine chemicals, and obtained a series of new systems of transition metal palladium and copper-catalyzed halogenated aromatic hydrocarbons involved in C-C and C-N coupling reactions; realized the efficient preparation of biphenyl, arylamine and aryl thioether compounds using water as solvent. Aiming at atomic economy, we realized t...
Squamous cell cancers of the head and neck (SCCHN), also known as head and neck cancers (HNC) encompass malignancies of the oral cavity, larynx, nasopharynx and pharynx, and are diagnosed in over 500,000 patients worldwide each year, accounting for 5% of all malignancies. It is estimated that approximately 50,000 patients develop head and neck cancer annually in the United States, of whom approximately 50% succumb to this cancer. For most cases of SCCHN, treatment is multimodal, often combining surgery or irradiation with chemotherapy; even successfully treated patients frequently experience durable and severe side effects. Improving cure rates and reducing chronic morbidity are urgent clini...
This book is a compilation of selected papers from the Fifth International Conference on Natural Resources and Sustainable Environmental Management held in Near East University, November 2021. It provides intellectual guidance and scientific evidence on the challenges of global warming and climate change based on a humanistic and critical thinking approach, promoting research and education to build equality in the global community and more sustainable societies. This book also addresses the current challenges of bridging the gap between government policymakers and providers of science and solutions with innovative ideas and new visions to help resolve the challenges facing us in the area of natural resources (water, energy), and environment.
This book provides readers with a comprehensive overview of the science of superconducting materials. It serves as a fundamental information source on the actual techniques and methodologies involved in superconducting materials growth, characterization and processing. This book includes coverage of several categories of medium and high-temperature superconducting materials: cuprate oxides, borides, and iron-based chalcogenides and pnictides. Provides a single-source reference on superconducting materials growth, characterization and processing; Bridges the gap between materials science and applications of superconductors; Discusses several categories of superconducting materials such as cuprate oxides, borides, and iron-based chalcogenides and pnictides; Covers synthesis, characterization, and processing of superconducting materials, as well as the nanoengineering approach to tailor the properties of the used materials at the nanoscale level.
The mechanical environment of the musculoskeletal system plays a fundamental role in orthopaedic diseases. Understanding the magnitude, pattern, and duration of biomechanical factors and how they impact surgical treatment is an ongoing topic of interest in biomechanics. However, the way forces and stresses acting on the skeletal system affect disease progression and treatment outcomes is not yet fully elucidated. As a result, investigating the biomechanical responses in the incidence and surgical treatment of orthopaedic diseases, such as osteoarthritis, can significantly enhance existing surgical treatment strategies and foster the development of new pharmaceutical interventions. Our goal is to consolidate groundbreaking studies in this field to advance the understanding of the biomechanical principles underlying disease progression and create a foundation for novel therapeutic strategies.
The tumour microenvironment (TME) is essential for cancer maintenance and is responsible for several antitumor characteristics, such as immune system avoidance, resistance to anticancer therapies, invasion, and metastasis. The TME is composed of several components, including fibroblasts, extracellular matrix proteins, pericytes, and immune cells. The immune cells, including T-lymphocytes, are responsible for fighting cancer cells, inducing cell death. However, cancer cells develop several mechanisms to avoid the immune system, including mutations to change the antigens originally recognised by T-cells. Tumours that can avoid the immune system, including the T-cell antitumor response, are kno...
This book contains the original peer-reviewed research papers presented at the 6th China Aeronautical Science and Technology Conference held in Wuzhen, Zhejiang Province, China, in September 2023. Topics covered include but are not limited to Navigation/Guidance and Control Technology, Aircraft Design and Overall Optimisation of Key Technologies, Aviation Testing Technology, Airborne Systems/Electromechanical Technology, Structural Design, Aerodynamics and Flight Mechanics, Advanced Aviation Materials and Manufacturing Technology, Advanced Aviation Propulsion Technology, and Civil Aviation Transportation. The papers presented here share the latest findings in aviation science and technology, making the book a valuable resource for researchers, engineers and students in related fields.
Microalgal Biofuels: Sustainable Production and Conversion is a comprehensive guide to the latest advancements in microalgal biofuels. The book provides systematic coverage of the processes of biofuel production, from microalgae biomass resources to biomass conversion processes and catalytic materials. It delves into the critical topic of sustainability, addressing LCA approaches to evaluate the environmental impacts of microalgal-based biofuels. It provides practical information and guidance on the latest strategies, opportunities, and challenges in the transition to sustainable bioenergy. This is an invaluable reference for students, researchers, and industrial practitioners working on bio...