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This book provides an overview on the organization and function of the microtubule cytoskeleton, which is essential to many cellular processes and profoundly linked to a range of human diseases. Covering basic concepts as well as molecular details, the book discusses how microtubules are nucleated and organized into ordered arrays, at different cell cycle stages and in distinct cell types. In addition, the book highlights how defects in the microtubule cytoskeleton are linked to diseases such as neurodevelopmental disorders. The book is intended for students, graduates and more senior researchers in cell and developmental biology as well as for medical doctors.
Lilly is finally old enough to babysit her brother Mac for the day, and she's thrilled because she gets to use her mom's smartphone! It's gearing up to be an exciting day -- until the hyper-allergic Mac discovers a dead bird. Lilly has to do her best to keep Mac safe and happy without ruffling anyone's feathers.
Research in optical information technology in Europe has been very active inrecent years. This volume records state-of-the-art research conducted in some 22 laboratories who have worked together within EC ESPRIT Basic Research Action 3199 up to 1992. The topics cover: (1) Active optical logic and switching devices - embracing new materials, nonlinear and electrooptic mechanisms as well as advanced device fabrication. These devices cover the range from all-optical nonlinear interferometer structures through hybrid optical-electronic modulators to integrated emitter-receiver structures. (2) The latest state of optical interconnect technology, embracing diffractive optics (binary and multi-level phase gratings), holographic space-variant elements and micro-refractive optics. (3) Contributions on optical information processing architecture and demonstrator projects. The materials base ranges from silicon to II-VI materials with the realisation of pn-junction devices in ZnSe. The research reported here lays the basis for long-term progress in devices for information processing.
Topic Editor Susan Richards is an employee of Sanofi and owns stock in the corporation. Topic Editor Bernard Maillere declares economic support from pharmaceutical companies (Novartis, Sanofi, and UCB) in the frame of collaborations aiming to evaluate the recognition by human T cells of therapeutic proteins and antibodies.
Robyn befriends unpopular Shelly. When he father wins tickets to a hockey game, she becomes popular.
Lilly has to make a decision: choose between old friends and the gang of cool kids.
This innovative study of the Montreal novel in French looks at how imaginary and material landscapes come together to produce a city of neighbourhoods.
Morgan is left out of the loop when everyone at school begins bringing their M8Y Game Wizards to school, linking up online with one another and playing at recess and lunch. Charlie lets Morgan use his M8Y every now and then, but clearly you''re not cool unless you have one. Poor Morgan is reduced to playing with Aldeen for something to do. Finally his parents relent, but Morgan learns that sometimes gaming is more trouble than it's worth. When Aldeen joins the gaming crew with her own player he faces tough decisions. Should he pull the plug about Aldeen's fake M8Y Game Wizard, or game on and leave her behind? Morgan, the most popular of all the characters featured in the First Novels collection, is at his loveable best in this topical, humorous, true-to-life story.
A new kid at school teases Aldeen, the Queen of Mean, and gets away with it!