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Where Do We Come From?
From the moment we first began to contemplate the world, three questions have occupied our minds: Where do we come from?, What are we?, and Where are we going? Artists, religious thinkers, philosophers, and most recently scientists have all searched for answers. Here, the authors describe how scientists decipher human origin from the record encrypted in the DNA and protein molecules. After explaining the nature of descent and the methods available for studying genealogical relationships, they summarize the information revealed by the molecular archives. In doing so, they draw conclusions about our identity, our place in the living world, and our future.
Unifying Biology
Unifying Biology offers a historical reconstruction of one of the most important yet elusive episodes in the history of modern science: the evolutionary synthesis of the 1930s and 1940s. For more than seventy years after Darwin proposed his theory of evolution, it was hotly debated by biological scientists. It was not until the 1930s that opposing theories were finally refuted and a unified Darwinian evolutionary theory came to be widely accepted by biologists. Using methods gleaned from a variety of disciplines, Vassiliki Betty Smocovitis argues that the evolutionary synthesis was part of the larger process of unifying the biological sciences. At the same time that scientists were working t...
Origin And Past Of Modern Humans As Viewed From Dna, The: Proceedings Of The Workshop On The Origin And Past Of Homo Sapiens Sapiens As Viewed From Dna - Theoretical Approach
This volume examines the origins, micro-evolution, diversification and adaptation of modern humans. It is based upon discrepancies between fossil evidence and molecular findings and between different investigators within each. This has given rise to much controversy that is not yet solved. The papers are presented in four methodological categories: theoretical, molecular, morphological and linguistic.
Molecular Evolution of the Major Histocompatibility Complex
From molecules to populations and back In biology, the most vigorous organisms often ensue from a union of two disparate, pure lines. In science, too, laws of hybrid vigor seem to operate at the interface between two disciplines, an interface that often proves to be fertile ground for germinating concepts and new outlooks. The fringes of research into the major histocompatibility complex (Mhc) have provided such an interface several times in the past and the encounters have invigorated fields such as transplantation biology, cellular immunology, and immunogenetics. In the last few years, a new interface has been emerging between Mhc and evolutionary genetics, and particularly the branch of e...
Gene Genealogies, Variation and Evolution: A primer in coalescent theory
Authored by leading experts, this seminal text presents a straightforward and elementary account of coalescent theory, which is a central concept in the study of genetic sequence variation observed in a population. Rich in examples and illustrations it is ideal for a graduate course in statistics, population, molecular and medical genetics, bioscience and medicine, and for students studying the evolution of human population and disease. It is also an invaluable reference for bioscientists and statisticians in the pharmaceutical industry and academia - ;Coalescent theory is a central concept in the study of genetic sequence variation that probabilistically describes the genealogy relating the...
Darwin, Then and Now
Darwin, Then and Now is a journey through the most amazing story in the history of science; encapsulating who Darwin was, what he said and what scientists have discovered since the publication of The Origin of Species in 1859. While recognized as one of the most influential individuals of the twentieth century, little is widely known about his personal life, interests, and motivations. This book explores Darwins driving passion using Darwins own words from The Origin of Species, Autobiography, Voyage of the Beagle and letters. In retracing the roots of evolution from the Greeks, Darwin, Then and Now journeys through the dynamics of the eighteenth century that lead to the publication of The O...
