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The purpose of this book is to highlight novel advances in the field and to incentivize scientists from a variety of fields to pursue angiogenesis as a research avenue. Blood vessel formation and maturation to capillaries, arteries, or veins is a fascinating area which can appeal to multiple scientists, students, and professors alike. Angiogenesis is relevant to medicine, engineering, pharmacology, and pathology and to the many patients suffering from blood vessel diseases and cancer, among others. We are hoping that this book will become a source of inspiration and novel ideas for all.
The volume contains essential information on elective (non-emergency) hand surgery practice. The author, M Merle, a world authority in surgery of the rheumatoid hand, synthesizes the depth of his experience into the book, and presents the management of these conditions in a clear manner. All the elective procedures are described in great detail and depth. The quality of illustrations is outstanding and is superior to any other hand textbooks on the market. There are very few textbooks on elective hand surgery and this will be an essential resource for orthopedic surgeons, rheumatologists, and physiotherapists.
Biological invasions by alien (non-native) species are widely recognized as a significant component of human-caused global environmental change and the second most important cause of biodiversity decline. Alien species threaten many European ecosystems and have serious environmental, economic and health impacts. The DAISIE (Delivering Alien Invasive Species Inventories for Europe) project has now brought together all available information on alien species in Europe (terrestrial, aquatic and marine) and from all taxa (fungi, plants, animals). Thus for the first time, an overview and assessment of biological invasions in the Pan-European region is finally possible. The Handbook of Alien Specie...
Membrane Receptors, Channels and Transporters in Pulmonary Circulation is a proceeding of the 2008 Grover Conference (Lost Valley Ranch and Conference Center, Sedalia, Colorado; September 3-7, 2008), which provided a forum for experts in the fields of those receptors, channels and transporters that have been identified as playing key roles in the physiology and pathophysiology of the pulmonary circulation. The book rigorously addresses: i) recent advances in our knowledge of receptors, channels and transporters and their role in regulation of pulmonary vascular function; ii) how modulation of expression and function of receptors, channels and transporters and their interrelationships contrib...
From school and residential segregation to increased pollution and aggressive policing in low-income neighborhoods, socioeconomic inequality is organized and reinforced through space and place. In this issue of RSF, editors George Galster and Patrick Sharkey and contributors present a new conceptual model for understanding space as one of the foundations of inequality. They bring together empirical research on neighborhoods, schools, and communities to demonstrate the extent to which people's environments influence their life chances. Articles in this issue explore the scale and dimensions of spatial inequality. Sean Reardon and coauthors develop a novel method of describing the joint distri...
This comprehensive reference expounds the current state of hormone therapy and castration resistance of prostate cancer (PCa). Previously, the incidence of PCa in Asian countries was relatively low, but it has been increasing dramatically in recent years. Although most of the new cases are diagnosed in early stages, a significant proportion of patients receive hormone therapy for metastatic disease or for relapse after local treatment. Thus the situation has gradually changed toward earlier and longer use of hormone therapy. The malignancy finally forms castration-resistant prostate cancer (CRPC) despite the lack of testicular androgen. With advances in understanding of the molecular basis o...
From Empathy to Denial is the first comprehensive investigation of Holocaust denial in the Arab world, and is based on years of painstaking historical research of mostly Arabic language sources. The authors explore how Holocaust denial emerged after the Second World War, how it paralleled the wider Arab-Israeli conflict after the establishment of the State of Israel in 1948 and how it subsequently became entangled with broader anti-Zionist and anti-Semitic sentiment. In particular Litvak and Webman look at the role of leading intellectuals, the media and other cultural forms in Egypt, Lebanon, Jordan and among the Palestinians and how their representation of the Holocaust has evolved in the last sixty years.
Kinase drug discovery remains an area of significant interest across academia and in the pharmaceutical industry. There are now around 13 FDA approved small molecule drugs which target kinases and many more compounds in various stages of clinical development. Although there have been a number of reviews/publications on kinase research, this book fills a gap in the literature by considering the current and future opportunities and challenges in targeting this important family of enzymes. The book is forward-looking and identifies a number of hot topics and key areas for kinase drug discovery over the coming years. It includes contributions from highly respected authors with a combined experie...
A pioneering researcher gives us a new understanding of stress and trauma, as well as the tools to heal and thrive. This groundbreaking book examines the cultural norms that impede resilience in America, especially our collective tendency to disconnect stress from its potentially extreme consequences and override our need to recover. It explains the science of how to direct our attention to perform under stress and recover from trauma, exploring how our survival brain and thinking brain react to traumatic situations differently. By directing our attention in particular ways, we can widen the window within which our thinking brain and survival brain work together cooperatively. When we use aw...