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Queríamos, e ainda queremos, de todas formas, pôr em evidência a potência em ato da Música Extrema como manifestação legítima de uma anti/contra/sub/outra cultura, que, se por um lado, não se submete aos ditames do capital, do Estado, da religião, da militarização, das hierarquias familiares patriarcais, ao mesmo tempo estava, por outro lado, recheada de contradições, violências e más contaminações da sociedade que essa mesma Música Extrema ansiava em rechaçar. O eBook é organizado por Rodrigo Barchi, Cristiano dos Passos, Cris Bahy e Guga Burkhardt, tendo acesso gratuito no site da Pimenta Cultural.
“Precisamos saudar esse livro, que dá continuidade aos Diálogos com a música extrema, de 2021, por trazer à baila um estilo de música que, de algum modo, podemos considerar como ‘marginal’, como ‘alternativo’, que engaja seus praticantes e amantes de modo intenso, visceral, como é a própria música produzida. Este livro nos provoca, nos incita, ao transitar por essas perturbações sonoras que não nos deixam parados, indiferentes”. (Sílvio Gallo, trecho do prefácio)
This book presents an authoritative review of the most significant findings about all the epigenetic targets (writers, readers, and erasers) and their implication in physiology and pathology. The book also covers the design, synthesis and biological validation of epigenetic chemical modulators, which can be useful as novel chemotherapeutic agents. Particular attention is given to the chemical mechanisms of action of these molecules and to the drug discovery prose which allows their identification. This book will appeal to students who want to know the extensive progresses made by epigenetics (targets and modulators) in the last years from the beginning, and to specialized scientists who need an instrument to quickly search and check historical and/or updated notices about epigenetics.
Mathematical problems such as graph theory problems are of increasing importance for the analysis of modelling data in biomedical research such as in systems biology, neuronal network modelling etc. This book follows a new approach of including graph theory from a mathematical perspective with specific applications of graph theory in biomedical and computational sciences. The book is written by renowned experts in the field and offers valuable background information for a wide audience.
In this provocative and now-classic work, Friedrich Engels explores the interrelated development of the family and the state from ancient society to the Victorian era. Drawing on new anthropological theories of his time, Engels argued that matriarchal communal societies had been overthrown by class society and its emphasis on private, not communal, property and monogamous, rather than polygamous, sexual organization. This historical development, Engels argued, constituted "the world-historic defeat of the female sex." A masterclass in the application of materialist thought to history and anthropology, and touching on love, monogamy, property, and the development of the human, this landmark work is still foundational in Marxist and socialist feminist theory.
This volume surveys advances in the study of adaptive radiation showing how molecular characters can be used to analyze the origin and pattern of diversification within a lineage in a non-circular fashion.
This brief goes back to basics and describes the Quantitative structure-activity/property relationships (QSARs/QSPRs) that represent predictive models derived from the application of statistical tools correlating biological activity (including therapeutic and toxic) and properties of chemicals (drugs/toxicants/environmental pollutants) with descriptors representative of molecular structure and/or properties. It explains how the sub-discipline of Cheminformatics is used for many applications such as risk assessment, toxicity prediction, property prediction and regulatory decisions apart from drug discovery and lead optimization. The authors also present, in basic terms, how QSARs and related ...
Habitus is a concept developed by the late French sociologist, Pierre Bourdieu, as a 'sense of one's place...a sense of the other's place'. It relates to our perceptions of the positions (or 'place') of ourselves and other people in the world in which we live and how these perceptions affect our actions and interactions with places and people. Habitus implies that a web of complex processes links the physical, the social and the mental. Inspired by this concept, this compelling book brings together leading scholars from interdisciplinary fields to examine ways in which spaces and places are constructed, interpreted and used by different people. This second edition contains updated chapter material, together with an entirely new introduction and revised conclusions which recognise the importance of Bourdieu's work. This publication is a tribute to Pierre Bourdieu's remarkable contribution to the fields of sociology, anthropology, geography, political philosophy and urban planning.
Biopolymeric Nanomaterials: Fundamentals and Applications outlines the fundamental design concepts and emerging applications of biopolymeric nanomaterials. The book also provides information on emerging applications of biopolymeric nanomaterials, including in biomedicine, manufacturing and water purification, as well as assessing their physical, chemical and biological properties. This is an important reference source for materials scientists, engineers and biomedical scientists who are seeking to increase their understanding of how polymeric nanomaterials are being used for a range of biomedical and industrial applications. Biopolymeric nanomaterials refer to biocompatible nanomaterials, co...
Systematically examining current methods and strategies, this ready reference covers a wide range of molecular structures, from organic-chemical drugs to peptides, Proteins and nucleic acids, in line with emerging new drug classes derived from biomacromolecules. A leader in the field and one of the pioneers of this young discipline has assembled here the most prominent experts from across the world to provide first-hand knowledge. While most of their methods and examples come from the area of pharmaceutical discovery and development, the approaches are equally applicable for chemical probes and diagnostics, pesticides, and any other molecule designed to interact with a biological system. Num...