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This volume draws together studies on the diverse group of calcium-activated chloride channels (CaCCS) in one comprehensive format. The characteristics of CaCCs identified in a number of different systems are described by experts in the field. Channels discussed include those described in cardiac, neuronal, endothelial and epithelial systems, in addition to sections on the CaCC of Xenopus Oocytes and the newly identified family of CLCA proteins. Key Features * Includes description of CaCCs in excitable and non-excitable tissues * Reviews identification and cloning of the CLCA protein family * Contains section on CaCCs in Xenopus Oocytes
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Some time in the 1840s, Narcisse, a young French sailor is abandoned on the coast of Australia and given up for dead by his shipmates. Seventeen years later he is found living among aboriginal peoples, having apparently forgotten everything of his original identity, including his native French language. Octave de Vallombrun, a well-meaning geographer, takes him under his wing and sets out to bring Narcisse, now known as the "white savage" back to civilisation and to find out what happened during those seventeen years.Observing Narcisse's struggle to adjust to the ways of the white man, Octave too begins to question his assumptions about what it means to be civilised, and to see in a new light the man known as the "white savage".
Joseph Valachi was a special figure in the history of American crime. Noteworthy as a rare primary source into Mafia events of the Castellammarese War-era (1930-1931), Valachi's documented memories also provide a window into the early gangland of East Harlem, Manhattan and the Bronx. Through his recollections, historians gain a unique soldier-level view of New York-area organized crime families between Prohibition and the Mafia convention at Apalachin, New York. As an early Mafia turncoat and a celebrated informant for J. Edgar Hoover's FBI, Valachi became the focus of a best-selling book, a popular motion picture, many hours of televised Senate testimony and a detailed but never published a...
This book uses the stories of early modern women in the Mediterranean who left their birthplaces, families, and religions to reveal the complex space women of the period occupied socially and politically. In the narrow sense, the word “renegade” as used in the early modern Mediterranean referred to a Christian who had abandoned his or her religion to become a Muslim. With Renegade Women, Eric R Dursteler deftly redefines and broadens the term to include anyone who crossed the era’s and region’s religious, political, social, and gender boundaries. Drawing on archival research, he relates three tales of women whose lives afford great insight into both the specific experiences and condi...
Things aren't going Dottie's way. Howard Hugues hasn't kept his promise to free Gary from the Russians, and Dottie isn't sure she'll succeed in helping him escape the gulag, or even in freeing herself from the ever-watchful eye of the megalomaniac billionaire. It seems nothing can be accomplished without the help of... Poison Ivy! This sixth volume beautifully concludes the second triptych of the "Pin-Up" series.
In its different presentations, headache is one of the most commonsymptoms seen by family practitioners. The difficulty is indiagnosing the cause of the headache so that the appropriatetreatment is provided, or if referral to a specialist is therecommended course of action. The ABC of Headache helps with this dilemma and guidesthe healthcare professional to look for the possible causes ofpresenting symptoms. Based on real case histories, each chapterguides the reader from symptoms through to diagnosis andmanagement. This new ABC is a highly illustrated, informative, andpractical source of knowledge. With links to further informationand resources, it is a valuable text for healthcare professionalsat all levels of practice and training.
Autoimmune Neurology presents the latest information on autoimmune neurologic disease, the immune response to the body where organs run wild, causing the immune system to attack itself. Autoimmunity is a main element in numerous nervous system diseases and can target any structure within the central or peripheral nervous system. Over the past 20 years, significant advances in our understanding of the pathophysiology of autoimmune disorders, including the use of biomarkers has led to new diagnosis and treatment options. Neurologic conditions associated with autoimmune reactions include dementia, neuromuscular disease, epilepsy, sleep disorders, diabetes, and other common neurologic disorders ...
Dementia, Parkinson's Disease, headache, and neuropathy are all conditions for which narrowly focused medical interventions all too often fall short. The first book in its field, Integrative Neurology synthesizes complementary modalities with state-of-the-art medical treatment to offer a new vision for neurological care. The authors begin by looking inward at the crisis of stress and burnout that confronts all of medicine, but neurology in particular. It goes on to provide a selective yet in-depth review of important topics in neurological practice from the perspective of integrative medicine. Taking an evidence based approach throughout, chapters cover chronic diseases such as Multiple Scle...
Mitochondrial Disorders in Neurology provides an overview of mitochondrial diseases. This book discusses the effects of mitochondrial dysfunction based on the relevant biochemistry and molecular genetics. The abnormal muscle and mitochondrial morphology in a variety of clinical presentations from isolated ophthalmoplegia to severe encephalopathy are also elaborated. This text likewise deliberates Leber's hereditary optic neuropathy, neurodegenerative disorders, and respiratory chain defects. Other topics covered include mitochondrial DNA and the genetics of mitochondrial disease; cytochrome ox ...