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Multiple Myeloma and Other Plasma Cell Neoplasms
  • Language: en
  • Pages: 247

Multiple Myeloma and Other Plasma Cell Neoplasms

  • Type: Book
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  • Published: 2018-02-16
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  • Publisher: Springer

This book is a comprehensive source of up-to-date information on plasma cell neoplasms. Key features include the provision of new criteria for the diagnosis of symptomatic multiple myeloma requiring treatment and the description of novel therapies for myeloma and other plasma cell neoplasms that have only very recently been licensed by the U.S. Food and Drug Administration. Examples include lenalidomide as first-line therapy, panobinostat in combination with bortezomib plus dexamethasone for relapsed/refractory myeloma, ibrutinib for Waldenström’s macroglobulinemia, and new therapeutic regimens for systemic amyloidosis and POEMS syndrome. Information is also provided on drug combinations that have shown encouraging results and are very near to approval. Other important aspects covered in the book are the role of different imaging modalities in workup and the significance of newly acquired data relating to prognosis and minimal residual disease. Readers will find Multiple Myeloma and Other Plasma Cell Neoplasms to be a rich source of knowledge that will be invaluable in improving patient management.

Asian Irrigation in Transition
  • Language: en
  • Pages: 536

Asian Irrigation in Transition

  • Type: Book
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  • Published: 2005-11-23
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  • Publisher: SAGE

Water will dominate discussion in the 21st century, this book is a collection of original essays written by leading international observers and experienced practitioners containing observations and informed views on what will be require of irrigation policies, institutions, and governance for Asia and for the rest of the world. Drawing vital lessons from the Asian experience, this essential book greatly assists in the design of efficient and equitable water management systems to meet the needs of users in the 21st century and outline an agenda for future research and development.

Water in a Changing World
  • Language: en
  • Pages: 437

Water in a Changing World

  • Type: Book
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  • Published: 2009-01-01
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  • Publisher: UNESCO

"The United Nations World Water Development Report", published every three years, is a comprehensive review providing an authoritative picture of the state of the world's freshwater resources. It offers best practices as well as in-depth theoretical analyses to help stimulate ideas and actions for better stewardship in the water sector. It is the only report of its kind, resulting from the collaboration and contributions of the 26 UN agencies, commissions, program, funds, secretariats and conventions that have a significant role in addressing global water concerns.

Immunomodulating Drugs for the Treatment of Cancer
  • Language: en
  • Pages: 318

Immunomodulating Drugs for the Treatment of Cancer

Immunomodulating Drugs for the Treatment of Cancer provides a comprehensive resource for clinicians and researchers regarding immunomodulatory (IMiDs) drugs and their rapidly emerging role in cancer medicine. This new class of anticancer agents has made a tremendous impact on the treatment of patients with various malignant diseases, including blood cancers and several cancers of the solid organs. Their popularity in prescribing is based on several important characteristics including: (1) oral bioavailability, (2) non-chemotherapeutic, (3) extremely well-tolerated in all age groups, (4) ability to activate patient's own immune response against cancer, (5) ease of combination with other agents such as chemotherapy resulting in higher responses as well as (6) variability of anticancer activity.

Land-water Linkages in Rural Watersheds
  • Language: en
  • Pages: 92

Land-water Linkages in Rural Watersheds

It is often assumed that upstream land use practices have important impacts on water resources and affect the downstream users at a watershed scale, Payments by downstream users to upstream users for "environmental services" such as good water quality, less sediments or more regular water flow are widely discussed. However, much controversy exists about the direction and magnitude of such impacts, how they influence the relationships between upstream and down-stream users, and which mechanisms allow for a sharing of resulting benefits and costs by all resource users in a watershed context. To address these issues, the FAO Land and Water Development Division organized the electronic workshop "Land-Water Linkages in Rural Watersheds" from 18 September to 27 October 2000. The present publication contains the proceedings of the workshop and two papers that set the stage for the workshop discussions. The complete workshop documentation, including discussion archive, background papers, and case studies, is included on the CD-ROM that accompanies the document.

Multiple Myeloma
  • Language: en
  • Pages: 349

Multiple Myeloma

Multiple myeloma is currently still an incurable disease, but during the past decade knowledge of its molecular pathogenesis has increased rapidly. This has led to remarkable progress in both diagnosis and therapy, including in particular the approval of novel and first-in-class drugs such as thalidomide, bortezomib, and lenalidomide. This book, written by internationally acknowledged experts, covers a wide range of topics relating to multiple myeloma, including history, epidemiology, pathophysiology, clinical features, staging, and prognostic systems. The principal focus, however, is on therapy, with detailed information on the various promising treatment options which give hope that this cancer will be transformed into a chronic disease or even become curable. Individualized therapy and the variety of supportive treatment options, as described in this volume, will help in achieving this goal, as well as in reducing adverse events and improving quality of life.

Contested Waterscapes in the Mekong Region
  • Language: en
  • Pages: 449

Contested Waterscapes in the Mekong Region

  • Type: Book
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  • Published: 2012
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  • Publisher: Earthscan

The water resources of the Mekong river catchment area, from China, through Thailand, Cambodia and Laos to Vietnam, are increasingly contested. Governments, companies and banks are driving new investment in roads, dams, diversions, irrigation schemes, navigation facilities, power plants and other emblems of conventional "development." Their plans and interventions pose multiple burdens and risks to the livelihoods of millions of people dependent on wetlands, floodplains, fisheries and aquatic resources.

Water for Food Water for Life
  • Language: en
  • Pages: 664

Water for Food Water for Life

  • Categories: Law
  • Type: Book
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  • Published: 2013-07-23
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  • Publisher: Routledge

Managing water resources is one of the most pressing challenges of our times - fundamental to how we feed 2 billion more people in coming decades, eliminate poverty, and reverse ecosystem degradation. This Comprehensive Assessment of Water Management in Agriculture, involving more than 700 leading specialists, evaluates current thinking on water and its interplay with agriculture to help chart the way forward. It offers actions for water management and water policy - to ensure more equitable and effective use. This assessment describes key water-food-environment trends that influence our lives today and uses scenarios to explore the consequences of a range of potential investments. It aims to inform investors and policymakers about water and food choices in light of such crucial influences as poverty, ecosystems, governance, and productivity. It covers rainfed agriculture, irrigation, groundwater, marginal-quality water, fisheries, livestock, rice, land, and river basins. Ample tables, graphs, and references make this an invaluable work for practitioners, academics, researchers, and policymakers in water management, agriculture, conservation, and development. Published with IWMI.

Handbook of Multiple Myeloma
  • Language: en
  • Pages: 109

Handbook of Multiple Myeloma

  • Type: Book
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  • Published: 2015-07-14
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  • Publisher: Springer

This handbook is an in-depth and comprehensive guide to the pathophysiology, diagnosis, staging, treatment and management of patients with multiple myeloma. The Handbook was commissioned to address an unmet need for a book of this kind in the myeloma field and to provide busy healthcare professionals with an informative and educational review of the current and emerging treatment recommendations for multiple myeloma. Myeloma is a type of bone marrow cancer arising from plasma cells and is the second most common form of bone marrow cancer, but represents just 1% of all cancers. The causes of myeloma are not fully understood but it is thought to be caused by an interaction of both genetic and environmental factors. This Handbook discusses these issues as well the latest developments in the field and will be an invaluable source of topical information for all healthcare professionals with an interest in multiple myeloma.

Rethinking the Approach to Groundwater and Food Security
  • Language: en
  • Pages: 68

Rethinking the Approach to Groundwater and Food Security

This study attempts to re-frame the current thinking on groundwater development and the implications for food security. Groundwater is important in agriculture as it provides a reliable fallback when rainfeeding fails. It is therefore instrumental in managing risk and optimizing food production. However accessing groundwater has become habit and turned to dependency. Resources limits on many key aquifers have been exceeded and competition for groundwater has become intense. This study highlights the role of adaptive strategies in dealing with aquifer management and indicates directions of research and management.