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This work is a guidebook for clinicians who are involved in treating depressive patients and also serves the research scientists who are working on the psychopharmacological mechanisms of antidepressant actions and psychopathological mechanisms underlying mood disorders. Mood disorders such as major depressive disorder (MDD), bipolar disorder (BPD) and seasonal affective disorder (SAD) are the most disabling disorders that are among the most expensive of all medical illnesses. The pathophysiology of mood disorders is very complex and involves many mechanisms like circadian rhythm disruption, sleep abnormalities, melatonin rhythm abnormalities and alterations in melatonin receptor mechanisms,...
Neuropsychiatric disorders such as schizophrenia, mood disorders, Alzheimer’s disease, epilepsy, alcoholism, substance abuse and others are one of the most debilitating illnesses worldwide characterizing by the complexity of the causes, and lacking the laboratory tests that may promote diagnostic and prognostic procedures. Recent advances in neuroscience, genomic, genetic, proteomic and metabolomic knowledge and technologies have opened the way to searching biomarkers and endophenotypes, which may offer powerful and exciting opportunity to understand the etiology and the underlying pathophysiological mechanisms of neuropsychiatric disorders. The challenge now is to translate these advances...
Winner of the 2020 PROSE Award for Earth Science! Exploring environmental changes through Earth’s geological history using chemostratigraphy Chemostratigraphy is the study of the chemical characteristics of different rock layers. Decoding this geochemical record across chronostratigraphic boundaries can provide insights into geological history, past climates, and sedimentary processes. Chemostratigraphy Across Major Chronological Boundaries presents state-of-the-art applications of chemostratigraphic methods and demonstrates how chemical signatures can decipher past environmental conditions. Volume highlights include: Presents a global perspective on chronostratigraphic boundaries Describe...
Now in its fully revised and expanded third edition, this comprehensive text represents a compilation of the critical endocrinology topics in the areas of sports medicine, kinesiology and exercise science, written by leading experts in the field. As in previous editions, the focus here is on the critical issues involved in understanding human endocrinology and hormonal workings with regards to physical activity, exercise and sport and how such workings impact the full range of medical conditions, overall health and physiological adaptation. Chapters included discuss the effect of exercise on the HPA axis, the GH-IGF-1 axis, thyroid function, diabetes, and the male and female reproductive sys...
Introduction -- Mesozoic depositional evolution -- Cenozoic depositional evolution -- Petroleum habitat.
This book provides a comprehensive summary of research to date in the field of stable iron isotope geochemistry. Since research began in this field 20 years ago, the field has grown to become one of the major research fields in "non-traditional" stable isotope geochemistry. This book reviews all aspects of the field, from low-temperature to high-temperature processes, biological processes, and cosmochemical processes. It provides a detailed history and state-of-the art summary about analytical methods to determine Fe-isotope ratios and discusses analytical and sample prospects.
Michael Moore has established himself as someone who just won't shut up, go away, or otherwise do what political and corporate fat cats would like him to do. He lifts the veil on the people who set themselves up as role models and exposes their vulnerable underbellies.