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Development of small molecules for disrupting pathological amyloid aggregation in neurodegenerative diseases
Neurodegenerative diseases (NDs), encompassing Alzheimer’s disease (AD), Parkinson’s disease (PD), and amyotrophic lateral sclerosis (ALS), are often characterized by the formation of pathological amyloid aggregates, predominantly composed of proteins like amyloid-β, tau, α-synuclein, TDP-43, and others. These amyloid aggregates inflict significant neuronal harm and incite inflammation. This review underscores the potential of small molecules as innovative therapeutic interventions, designed to influence the formation, stability, and breakdown of these pathological amyloid aggregates, which could potentially modify the disease’s progression and minimize its neurotoxic effects. This r...
Contemporary Research on E-business Technology and Strategy
This book constitutes the proceedings of the International Conference on E-business and Strategy, iCETS 2012, held in Tianjin, China, in August 2012. The 65 revised full papers presented were carefully reviewed and selected from 231 submissions. The papers feature contemporary research on developments in the fields of e-business technology, information management systems, and business strategy. Topics addressed are latest development on e-business technology, computer science and software engineering for e-business, e-business and e-commerce applications, social networking and social engineering for e-business, e-business strategic management and economics development, e-business education, entrepreneurship and e-learning, digital economy strategy, as well as internet and e-commerce policy.
Ancient and Early Medieval Chinese Literature (vol.I)
The long-awaited, first Western-language reference guide, this work offers a wealth of information on writers, genres, literary schools and terms of the Chinese literary tradition from earliest times to the seventh century C.E.
A History of Contemporary Chinese Literature
"A thorough overview and analysis of the literary scene in China during the 1949-1999 period, focusing primarily on fiction, poetry, drama, and prose writing"--Provided by publisher.
Super Clairvoyant Farmer Immortal
His life was turned upside down by his sudden acquisition of martial arts skills and clairvoyance. After Li Tianyi's blood accidentally touched a stone, the stone turned into a shining white light and entered his forehead. At this moment, a lot of knowledge about practicing martial arts appeared in Li Tianyi's mind, and at the same time, he also found that his eyes actually had a perspective function! As long as he looks at the plants with his divine eyes, the plants that were seedlings the day before will become fruitful the next day. Some men who were jealous of him in the village succumbed under his mighty force. With excellent martial arts and perspective eyes, Li Tianyi's life in the countryside is flourishing. ☆About the Author☆ Huan Shou Dao, a well-known online novelist, has authored many urban fantasy novels. He has rich imagination and creative skills, which loved by many readers.
Daily Report
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Daily Report
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China Report
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Mountain Fires
"A milestone marking a new maturity in studies of Chinese Communist history."--John S. Service, UC, Berkeley "A milestone marking a new maturity in studies of Chinese Communist history."--John S. Service, UC, Berkeley
