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A comprehensive compendium of scholarly contributions relating to bacterial virulence gene regulation. • Provides insights into global control and the switch between distinct infectious states (e.g., acute vs. chronic). • Considers key issues about the mechanisms of gene regulation relating to: surface factors, exported toxins and export mechanisms. • Reflects on how the regulation of intracellular lifestyles and the response to stress can ultimately have an impact on the outcome of an infection. • Highlights and examines some emerging regulatory mechanisms of special significance. • Serves as an ideal compendium of valuable topics for students, researchers and faculty with interests in how the mechanisms of gene regulation ultimately affect the outcome of an array of bacterial infectious diseases.
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Since the initial establishment of Robert Koch’s postulates in the nineteenth century, microbial protein toxins have been recognized as a major factor of bacterial and fungal virulence. An increasing number of proteins produced and secreted by various bacteria, yeasts and plants are extremely toxic and most of them developed remarkably "intelligent" strategies to enter, to penetrate and to finally kill a eukaryotic target cell by modifying or blocking essential cellular components. This book describes the strategies employed by protein toxins to render their pro- and eukaryotic producers a selective growth advantage over competitors. In providing an up-to-date overview on the mode of protein toxin actions, it accommodates biomedically and biologically relevant toxin model systems. As a result, it significantly broadens our perspective on biochemical architecture and molecular ploy behind the lethal principles of pro- and eukaryotic toxins.
This much-anticipated third edition again consolidates the knowledge of more than twenty experts on pathogenesis of animal disease caused by various species or groups of bacteria. Emphasizing pathogenic events at the molecular and cellular levels, the editors and contributors place these developments in the context of the overall picture of disease. Pathogenesis of Bacterial Infections in Animals, Third edition, updates and expands the content of the second edition and includes cutting-edge information from the most current research. Comments on previous editions: "...highly recommended." --The Veterinary Record "...a comprehensive, complete and easy-to-use source of information." --Veterina...
The molecular age has brought about dramatic changes in medical microbiology, and great leaps in our understanding of the mechanisms of infectious disease. Molecular Medical Microbiology is the first book to synthesise the many new developments in both molecular and clinical research in a single comprehensive resource. This timely and authoritative three-volume work is an invaluable reference source of medical bacteriology. Comprising more than 100 chapters, organized into 17 major sections, the scope of this impressive work is wide-ranging. Written by experts in the field, chapters include cutting-edge information, and clinical overviews for each major bacterial group, in addition to the la...
Diseases affecting the skin have tended to provoke a response of particular horror in society. This collection of essays uses case studies to chart the medical history of skin from the eighteenth to the twentieth century.
This book focusses on the toxicological aspects of aerobiology, considering the adverse health effects associated with the inhalation of airborne biological particulates.
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Precision farming is an agricultural management system using global navigation satellite systems, geographic information systems, remote sensing, and data management systems for optimizing the use of nutrients, water, seed, pesticides and energy in heterogeneous field situations. This book provides extensive information on the state-of-the-art of research on precision crop protection and recent developments in site-specific application technologies for the management of weeds, arthropod pests, pathogens and nematodes. It gives the reader an up-to-date and in-depth review of both basic and applied research developments. The chapters discuss I) biology and epidemiology of pests, II) new sensor technologies, III) applications of multi-scale sensor systems, IV) sensor detection of pests in growing crops, V) spatial and non-spatial data management, VI) impact of pest heterogeneity and VII) precise mechanical and chemical pest control.