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Motor neuron diseases (MNDs) are a group of progressive neurodegenerative disorders associated with the degradation of the upper (UMN) or lower motor neurons (LMN) or both. They encompass amyotrophic lateral sclerosis (ALS), spinal muscular atrophy (SMA), spinobulbar muscular atrophy (SBMA), hereditary spastic paraparesis (HSP), and others. MND patients present with a wide variety of clinical symptoms, including muscular weakness, atrophy, and corticospinal tract signs in diverse combinations. Over recent years, considerable collaborative efforts have been made to unravel the underlying pathophysiology of MNDs and find novel therapeutic interventions. With this book, we aim to provide both professionals and the general public with an outline of the latest scientific advances regarding the genetics, pathophysiology, diagnostics, and treatment options for MNDs. Researchers from different parts of the world have contributed to this volume in order to create a comprehensive multidisciplinary overview of the topics.
This first of two volumes on EMG (Electromyography) covers a wide range of subjects, from Principles and Methods, Signal Processing, Diagnostics, Evoked Potentials, to EMG in combination with other technologies and New Frontiers in Research and Technology. The authors vary in their approach to their subjects, from reviews of the field, to experimental studies with exciting new findings. The authors review the literature related to the use of surface electromyography (SEMG) parameters for measuring muscle function and fatigue to the limitations of different analysis and processing techniques. The final section on new frontiers in research and technology describes new applications where electromyography is employed as a means for humans to control electromechanical systems, water surface electromyography, scanning electromyography, EMG measures in orthodontic appliances, and in the ophthalmological field. These original approaches to the use of EMG measurement provide a bridge to the second volume on clinical applications of EMG.
This volume contains proceedings of two conferences held in Toronto (Canada) and Kozhikode (India) in 2016 in honor of the 60th birthday of Professor Kumar Murty. The meetings were focused on several aspects of number theory: The theory of automorphic forms and their associated L-functions Arithmetic geometry, with special emphasis on algebraic cycles, Shimura varieties, and explicit methods in the theory of abelian varieties The emerging applications of number theory in information technology Kumar Murty has been a substantial influence in these topics, and the two conferences were aimed at honoring his many contributions to number theory, arithmetic geometry, and information technology.