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"Ordinary Economies in Japan directs our attention to a subordinate yet powerful theme in modern Japanese economic thought that appeared unobtrusively in the mid-Tokugawa period and found expression in the formation of voluntary, non-hierarchical associations of commoners who purposively organized their self-help activities apart from state authority. Tetsuo Najita's compelling analysis of kô is groundbreaking and explains a great deal about Japanese modernization that economic historians have overlooked or undervalued."—Stephen Vlastos, University of Iowa
This book describes the precise mechanisms by which insulin resistance and diabetes mellitus (DM) act as risk factors for Alzheimer’s disease (AD). It opens by discussing the de novo synthesis of insulin in the brain and its functional significance with regard to glucose metabolism and maintenance of neuronal function in the brain. The epidemiological evidence that DM is a risk factor for the development of dementia, including AD as well as vascular dementia, is then examined. Subsequent chapters explore in depth the mechanisms involved in this relationship, including abnormal protein processing, dysregulated glucose metabolism, impaired insulin signaling, and mitochondrial dysfunction. The molecular interactions between diabetes and AD are fully discussed, highlighting the pathological molecular mechanisms induced by diabetes that promote and accelerate AD pathology. Finally, diagnostic biomarkers and potential therapeutic approaches for AD are considered on the basis of the presented evidence. In providing answers to the critical questions of whether and why DM is a risk factor for AD, this book will hold appeal for a wide interdisciplinary audience.
Examines psychiatric epidemiology's unique evolution, conceptually and socially, within and between diverse regions and cultures, underscoring its growing influence on the biopolitics of nations and worldwide health campaigns.
This book sheds new light on health issues that concern both aging patients and their caregivers, and provides practical and in-depth insights. The respective chapters address various topics including locomotive organ disease, cardiovascular disease, diabetes mellitus, chronic kidney disease and more. Japan is currently experiencing a massive growth in its elderly population, and at a speed unmatched elsewhere in the world. As such, this edited volume offers a valuable guide for countries that are likely to experience an increase in their elderly population, especially with regard to the epidemiological findings and cohort studies in Japan that it presents. Health Issues and Care System for the Elderly offers a valuable resource for both new and established researchers, doctors, healthcare workers, and students who are seeking information on health problems involving the elderly in the field of public health and gerontology.
This book delves into the delicate realm of neurodegenerative illnesses, navigating the vast landscape of molecular targets with care and purpose. Researchers are studying the complex pathways involved in diseases such as Alzheimer’s, Parkinson’s, and Huntington’s in order to identify specific molecules that could be targeted for therapy. The present work explores potential methods of intervention by carefully analysing neural circuits, protein misfolding, and genetic predispositions, unravelling the complexities of the human mind by focusing on individual molecular targets. As new findings emerge, reducing the severe consequences of neurodegenerative illnesses becomes increasingly possible, providing optimism for millions of people throughout the world.
China's Tianjin Binhai New Area and the Tianjin Economic-Technological Development Area commissioned a technology-foresight study to help them plan for economic growth. The authors recommend seven emerging technology applications (TAs)--solar energy, mobile communications, rapid bioassays, new water-purification systems, molecular-scale drugs, electric and hybrid vehicles, and green manufacturing--and describe drivers, barriers, and plans for each.
The American Heart Association’s Scientific Sessions 2016 is bringing big science, big technology, and big networking opportunities to New Orleans, Louisiana this November. This event features five days of the best in science and cardiovascular clinical practice covering all aspects of basic, clinical, population and translational content.
The American Heart Association’s Scientific Sessions 2019 is bringing big science, big technology, and big networking opportunities to Philadelphia, Pennsylvania this November. This event features five days of the best in science and cardiovascular clinical practice covering all aspects of basic, clinical, population and translational content.
The increasingly widespread implementation and use of intelligent assistive technologies (IATs) is reshaping dementia care. This volume provides an up-to-date overview of the current state of IATs for dementia care. The new essays collected here examine what IATs will mean for clinical practice and the ethical and regulatory challenges they will pose.