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Periodontitis is a disease that affects more than half the adult population in the world. Treatment is often based on ancient recommendations consisting in mechanically removing material from damaged zones. However, novel therapeutic management strategies exist, from prevention to efficient treatment, and regeneration. The need of integrative approaches to circumvent this worldwide pledge can be achieved through: A better understanding of this complex disease by promoting scientific research and a comprehensive multidisciplinary approach, including epidemiology, microbiology, immunology, physiology, therapeutics, psychology, etc. A better outreach by promoting vulgarization and recommendatio...
Higher education policy has increasingly gained a European dimension, with its own distinct influence over national education policies. Against this background, a major project was launched, the REFLEX project, which aims to make a contribution to assessing the demands that the modern knowledge society places on higher education graduates, and the degree to which higher education institutions in Europe are up to the task of equipping graduates with the competencies needed to meet these demands. The project also looks at how the demands, and graduates’ ability to realise them, is influenced by the way in which work is organised in firms and organisations. The REFLEX project has been carried out in sixteen different countries and consisted of a large scale survey among some 70.000 graduates. This report presents the major findings and draws important policy implications.
Study with particular reference to Dutch economic assistance to India.
Indispensable for dentists, dental students and community dental programs With the mass-marketed introduction of fluoride in toothpaste in the 1950s, toothbrushing with paste became indispensable for good oral health. Both the industry and the dental profession had a shared interest in advocating the widespread correct use of good quality toothpaste. This publication starts with a general introduction on the purpose, history and composition of toothpaste. The following chapters deal with the clinical evidence of its effectiveness in caries prevention, reducing and preventing plaque, gin-givitis, halitosis, and calculus formation, facilitating removal and prevention of extrinsic stain, and pr...
The proteolytic enzymes have an essential function in all cells. Their activities are regulated by the rate of synthesis, activation of proenzymes and by the rate of synthesis of their inhibitors. They are synthesized in ribosomes like any other proteins and transported to various storage organelles or secreted from the cells and are activated in the pericellular space or in interstitium. Various cells and tissues have their characteristic enzyme patterns which serve their specific functions. Proteolytic enzymes take part and often have a regulatory role in numerous phases of cell function, e.g. cell division, migration, apoptotic as well as necrotic cell death etc. Diseases in which proteolysis has been subject of active research are e.g. cancer metastasis, viral infections, e.g. HIV, and Alzheimer's disease. They are also an essential part in any tissue remodelling, wound healing, throughout the kingdom of fauna and flora.
The oral cavity harbors an immense diversity of microorganisms, including bacteria, fungi, archaea, protozoa and viruses. At health, oral microbial community is thought to be in a state of homeostasis, even after numerous perturbations (e.g., toothbrushing, food intake) a day. The breach in this homeostasis can occur for instance if the perturbations become too excessive (e.g., frequent carbohydrate intake leading to acidification of the community) or the host is compromised (e.g., inadequate immune response resulting in persistent inflammation of periodontal tissue). Aggressive antimicrobial therapy (e.g., antibiotics in case of periodontal disease or preventive antibiotic therapy before an...
The aim of this comprehensively written volume is to provide a baseline of information on the normal microflora at various sites in the body. It focuses on the mouth, upper digestive tract, large intestine, skin, and urinogenital tract. Written in an easy-to-read format, this book highlights the level of detail available. For example, it explains that in the mouth and colon the data are extremely detailed and good quantitative information is available on large numbers of bacterial species. This work analyzes the similarities and differences between the microfloras of the various "internal" surfaces, and discusses the clear value of good taxonomy. It focuses on problems and extended research in the progress at other sites. Because this work researches the advances and discoveries made in specific areas of human microbial ecology, it is an ideal source for all who are involved in microbiology, bacteriology, and infectious diseases.
This book provides the why, what and how on delivering a sustainable dental practice. Dentists have a professional duty to support optimal oral health. They also have a moral duty to do so in a way that leaves the smallest footprint on this planet and takes their impacts on the environment and society into account. This book helps the reader to develop a sustainable practice, driven by prevention and delivering the right care at the right time and at the right place, within systems of universal, needs-based access to care. Readers learn how to opt for a practice that is supplied with sustainable energy and encourages biodiversity while building models of care that maximize remote patient engagement and avoid travel. Clear guidance is given on responsible decontamination, waste management and environmentally sensitive ways of managing people with anxiety or behavioural difficulties within the dental setting. The future of dentistry products and innovations to reduce environmental impacts in the dental practice are discussed. This book is a must-have for dentists, dental students and all members of the dental team.
Measuring competencies acquired over the course of higher education is an area of research that largely has been neglected. This deficit can be attributed to the complexity of academic competencies since the variety of institutions, programs, occupational fields and job requirements render it difficult to define and even harder to measure outcomes. Thus, assessing the preconditions for and effects of competency development is a challenge methodologically. In this book, a comprehensive review of the international state of research on modeling and measuring competencies in higher education across several academic disciplines is presented, along with an evaluation of the field’s strengths and...