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This handbook of the series Biomarkers in Disease informs comprehensively about all aspects of monitoring and detecting toxicity in the human body and model organisms. Biomarkers for assessing toxicity in diverse organs are presented and different assays and methods are explained. Single compounds and drugs and their toxicity for humans are shown and the methods for detection described. Similar to all the volumes of the Biomarkers in Disease series, the chapters are written by experts in their field, each chapter features key facts summarizing the most important aspects of its respective topic and the definitions of words and terms facilitate the reading and understanding. This handbook is a must-have for researchers in toxicology and biomedicine who analyze the effects of drugs and various other substances in the human body and in model organisms. It also serves as a thorough guide for clinicians and pharmacologists.
This book, Telomere - A Complex End of a Chromosome, is organized into nine chapters containing the latest aspects of the current knowledge about the structure of telomeres and the crucial role that telomerase plays not only in maintaining chromosomal stability but also in relation to cell immortality, cell instability, and cancer biology. We now appreciate that these unusual complexes of DNA and proteins we all know as "telomeres" are dynamic and key structures that depend on telomerase and other cellular factors for continuance. Regulation of telomere activity is a dynamic area of current research, and new insights into telomeres and their role in aging and cancer, among other biological functions and pathologies, appear regularly in the scientific world. However, one fact is more than understandable in this difficult biological conundrum: the end of the telomere story is far from being totally unraveled.
This book reviews the chemical, regulatory, and physiological mechanisms of protein arginine and lysine methyltransferases, as well as nucleic acid methylations and methylating enzymes. Protein and nucleic acid methylation play key and diverse roles in cellular signalling and regulating macromolecular cell functions. Protein arginine and lysine methyltransferases are the predominant enzymes that catalyse S-adenosylmethionine (SAM)-dependent methylation of protein substrates. These enzymes catalyse a nucleophilic substitution of a methyl group to an arginine or lysine side chain nitrogen (N) atom. Cells also have additional protein methyltransferases, which target other amino acids in peptidy...
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
In early eleventh century Zaragoza, the eminent Jewish scholar Abū l-Walīd Marwān ibn Janāḥ wrote a glossary containing almost 1100 entries, entitled Kitāb al-Talkhīṣ. This important text, considered lost until recently, contains Arabic and foreign-language names of simple drugs, weights, measures, and other medical terms. In the present volume, the Kitāb al-Talkhīṣ is edited and translated for the first time by Gerrit Bos and Fabian Käs. In detailed commentaries, the editors identify the substances mentioned in the Talkhīṣ. They also elaborate on the role of the text in the history of Arabic glossaries concerned with medical nomenclature. Special attention is paid to Ibn Janāḥ’s Ibero-Romance phytonyms, analysed in depth by Mailyn Lübke and Guido Mensching.
Monograph of selected articles on psychological aspects of educational technology - covers teacher training, teaching and teaching method, scholastic aptitude, the gifted and the disabled children, personality, motivation, behavioural attitudes, creative thinking, computer assisted instruction, etc. Bibliography pp. 375 to 386.
Vitamin C is one of the most important components to include in a regular diet. It is a powerful vitamin that provides a number of very important health benefits and affects multiple body processes. This book aims to gather valuable information about this important vitamin, including sources of this nutrient with such important biological properties, the effects of processing and a number of different approaches to the roles of this powerful vitamin in the human body, as expressed by the diversity of themes addressed in the chapters.
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