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Endocrinology: Adult and Pediatric E-Book
Considered the definitive source in its field for over 35 years, Endocrinology: Adult and Pediatric, has been thoroughly updated to reflect today's recent advances in adult and pediatric endocrinology. Unique perspectives from a team of trusted, world-renowned experts ensure this medical reference book remains the most highly-regarded text in the field. Make the best clinical decisions with an enhanced emphasis on evidence-based practice and expert opinions on treatment strategies. Zero in on the most relevant and useful references with the aid of a more focused, concise bibliography. Locate information quickly, while still getting the complete coverage you expect. Now in full color, with sp...
Personalized Medicine and Neurosurgery
The Precision Medicine Initiative, which was instituted by President Barack Obama on January 20, 2015, highlighted the importance that advances in genomics and related “-omic” approaches have made to science and medicine, and it set the stage for their federally funded and mandated integration into the delivery of health care. Whether these advances comprise large-scale approaches, such as The Cancer Genome Atlas, which provides a modern classification of cancers based on molecular profiles, or genealogy initiatives, which seek to trace the movement of our early ancestors out of Africa, genomic technology has taken us closer to developing targeted therapies and a refined understanding of...
Management Dilemmas at the Junction of Neurocritical Care and Neurosurgery: What is the Evidence?
Effectively treat life-threatening diseases of the nervous system using the latest evidence-based information and insights Covering the most important literature on the topic, Management Dilemmas at the Junction of Neurocritical Care and Neurosurgery provides the latest evidence-based information and insights for improving patient outcomes across various clinical scenarios. It reviews landmark studies over the last 30 years, covering the issues you’re most likely to encounter. Nearly every study included has been published in the best general medicine peer-reviewed journals and has been highlighted in the lay press upon publication. Most are multi-institutional, prospective, randomized controlled trials that have helped shape modern neurosurgery and neurocritical practice guidelines. Chapters include: • Intracerebral Hemorrhage • Subarachnoid Hemorrhage • Traumatic Brain Injury • Status Epilepticus • Stroke • Neurovascular Neurosurgery • Neuro-oncology • Spine Injury • Functional and Epilepsy Surgery
Biological and Clinical Landscape of Meningiomas
"Meningiomas are tumors that originate from the arachnoidal cap cells of the leptomeninges. With an incidence rate of 8.36 per 100, 000 population, they are the most common primary central nervous system (CNS) tumors, accounting for a third of all cases. The World Health Organization (WHO) classification has traditionally categorized meningiomas into 15 different histopathological subtypes and three clinical grades. Tumors are classified as WHO grades 1, 2 or 3 based largely on histopathological features such as mitotic activity, presence of brain invasion, and other atypical features. However, there is increasing recognition of the limitations of histopathology including but not limited to:...
Youmans and Winn Neurological Surgery E-Book
Widely regarded as the definitive reference in the field, Youmans and Winn Neurological Surgery offers unparalleled, multimedia coverage of the entirety of this complex specialty. Fully updated to reflect recent advances in the basic and clinical neurosciences, the 8th Edition covers everything you need to know about functional and restorative neurosurgery, deep brain stimulation, stem cell biology, radiological and nuclear imaging, and neuro-oncology, as well as minimally invasive surgeries in spine and peripheral nerve surgery, and endoscopic and other approaches for cranial procedures and cerebrovascular diseases. In four comprehensive volumes, Dr. H. Richard Winn and his expert team of e...
Pediatric Endoscopic Endonasal Skull Base Surgery
The definitive state-of-the-art resource on pediatric endoscopic endonasal approaches Today, expanded endonasal approaches (EEA) have revolutionized the surgical treatment paradigm for pediatric central skull base lesions. Specially adapted micro-instruments have been developed to permit passage through the narrow sinonasal pathways in children, enabling access to the entire midline skull base, from the crista galli to the cervico-medullary junction. Pediatric Endoscopic Endonasal Skull Base Surgery by Harminder Singh, Jeffrey Greenfield, Vijay Anand, and Theodore Schwartz is the first textbook focused solely on endoscopic endonasal management of cranial base pathologies in children. The boo...
Chordomas
A rare form of cancer, chordomas are among the most difficult tumors to treat, requiring highly specialized training and surgical expertise. Although generally slow-growing, chordomas present resection challenges due to their proximity to critical structures including the spinal cord, brainstem, nerves, and arteries. Written by an impressive cadre of internationally-renowned experts, this textbook is the most current, concise, and definitive resource on diagnosis and management of this complex pathology. Acclaimed surgeons from Brazil, Canada, Japan, Turkey, the USA, and the UK are contributors. The book starts with a historical overview, epidemiology, molecular pathogenesis, cytogenetics, l...
