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"Soft as water." Han Yu, who was carrying the delicate woman in his arms, instantly opened his eyes with his mouth wide open. He was so shocked that he could swallow a goose egg. "Eh? Didn't I get slapped to death by the Sect Master? "
The book is a multi-author survey (in 15 chapters) of the current state of knowledge and recent developments in our understanding of oxide surfaces. The author list includes most of the acknowledged world experts in this field. The material covered includes fundamental theory and experimental studies of the geometrical, vibrational and electronic structure of such surfaces, but with a special emphasis on the chemical properties and associated reactivity. The main focus is on metal oxides but coverage extends from 'simple' rocksalt materials such as MgO through to complex transition metal oxides with different valencies.
This volume looks at applications of artificial intelligence (AI), machine learning (ML), and deep learning (DL) in drug design. The chapters in this book describe how AI/ML/DL approaches can be applied to accelerate and revolutionize traditional drug design approaches such as: structure- and ligand-based, augmented and multi-objective de novo drug design, SAR and big data analysis, prediction of binding/activity, ADMET, pharmacokinetics and drug-target residence time, precision medicine and selection of favorable chemical synthetic routes. How broadly are these approaches applied and where do they maximally impact productivity today and potentially in the near future. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary software and tools, step-by-step, readily reproducible modeling protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and unique, Artificial Intelligence in Drug Design is a valuable resource for structural and molecular biologists, computational and medicinal chemists, pharmacologists and drug designers.
"Soft as water." Han Yu, who was carrying the delicate woman in his arms, instantly opened his eyes with his mouth wide open. He was so shocked that he could swallow a goose egg. "Eh? Didn't I get slapped to death by the Sect Master? "
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"Soft as water." Han Yu, who was carrying the delicate woman in his arms, instantly opened his eyes with his mouth wide open. He was so shocked that he could swallow a goose egg. "Eh? Didn't I get slapped to death by the Sect Master? "
As the largest expenditure category of the health systems in both industrialised and developing countries, hospital care provision has been the focus of reforms over recent decades. This publication reviews recent trends in hospital policy reforms and options around the world; and includes case studies which offer insights into lessons learned. Issues considered include: differences in income levels, cultural settings and market environments; organisational changes such as increased management autonomy and privatisation; the need for parallel reforms and effective evaluation mechanisms.