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Autophagy, Infection, and the Immune Response
The relationship between infection and immunity and autophagy, a pathway of cellular homeostasis and stress response, has been a rapidly growing field of study over the last decade. While some cellular processes are pro- or anti-infection, autophagy has been proven to be both: a part of the innate immune response against some microbes, and a cellular pathway subverted by some pathogens to promote their own replication. Autophagy, Infection, and the Immune Response provides a unified overview of the roles of cellular autophagy during microbial infection. Introductory chapters ground the reader by delineating the autophagic pathway from a cellular perspective, and by listing assays available f...
Multi Agent Systems
Research on multi-agent systems is enlarging our future technical capabilities as humans and as an intelligent society. During recent years many effective applications have been implemented and are part of our daily life. These applications have agent-based models and methods as an important ingredient. Markets, finance world, robotics, medical technology, social negotiation, video games, big-data science, etc. are some of the branches where the knowledge gained through multi-agent simulations is necessary and where new software engineering tools are continuously created and tested in order to reach an effective technology transfer to impact our lives. This book brings together researchers w...
Community Series in Antiviral Innate Immune Sensing, Regulation, and Viral Immune Evasion, volume II
This Research Topic is the second volume of the “Community Series in Antiviral Innate Immune Sensing, Regulation, and Viral Immune Evasion”. Please see the first volume here. The innate immune system is crucial to defend against viruses or other pathogenic microbes in the early phases of infection. The response starts with detecting evolutionarily conserved structures, termed pathogen-associated molecular patterns (PAMPs), by a set of germline-encoded pattern-recognition receptors (PRRs). Following the detection of specific viral PAMPs, PRRs trigger the activation of intracellular signaling cascades, ultimately leading to the induction of type I interferons (IFNs), pro-inflammatory cytok...
International Symposium on World Ecological Design
With the world facing increasingly serious global climate change and resource scarcity issues, ecology and the environment have received much attention in recent years. As a major factor in human activity, design plays an important part in protecting the environment, as does the role of digital technology in finding solutions to the pressing problems faced in this regard. This book presents the proceedings of ISWED2023, the International Symposium on World Ecological Design, held on 17 December 2023 in Guangzhou, China. Sponsored by the World Eco-Design Conference (a UN Consultative NGO), the conference provides a platform for professionals and researchers from industry and academia to prese...
Ubiquitin and Autophagy
This book is a collection of articles from the Cells Special Issue on “Ubiquitin and Autophagy”. It contains an Editorial and 13 articles at the intersection of ubiquitin- and autophagy-related processes. Ubiquitin is a small protein modifier that is widely used to tag proteins, organelles, and pathogens for their degradation by the ubiquitin–proteasome system and/or autophagy–lysosomal pathway. Interestingly, several ubiquitin-like proteins are at a core of the autophagy mechanism. This book dedicates a lot of attention to the crosstalk between the ubiquitin–proteasome system and autophagy and serves as a good starting point for the readers interested in the current state of the knowledge on ubiquitin and autophagy.
Silencing Chinese Media
Chinese media in the reform era walk a fine line between commercialized diversification and party-state control. Nowhere have these two trends been in more open conflict than at Southern Weekly (Nanfang Zhoumo), a Guangzhou-based newspaper known for reliably pushing the envelope on media controls. Soon after a new group of political leaders rose to power in early 2013, these tensions boiled over, with censors making draconian cuts to the paper’s New Year’s edition. Fiery debates raged inside the paper about how to push back against ever-tightening constraints on reporting, while daring public protests outside the paper’s headquarters demanded freedom of speech. As the protests came to an end, the party-state’s hold on media had only tightened. Silencing Chinese Media, a gripping insider’s account of these events, highlights the tensions inherent within the program of “reform and opening” and foreshadows the challenges facing Chinese media and civil society in this new era.
