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Microspheres and Microcapsules in Biotechnology
Microspheres and microcapsules have very broad applications in various fields, especially in those of biotechnology and biopharmaceuticals, as targeting drug–delivery carriers, separation media for protein, peptide, DNA, and so forth. It is a big challenge to design and prepare microspheres and microcapsules of different sizes and structures from various materials and develop new techniques. This book focuses on new microspheres and microcapsules specifically designed and prepared for application in the fields of biotechnology and biopharmaceuticals involving bioreaction, bioseparation, bioformulation, biodetection, and other new bioapplications. It provides a deep knowledge about the principles of design, preparation methods, and application results of new microspheres and microcapsules for each bioapplication area. The book also presents problems that need to be studied further and comments on the future prospects of microspheres and microcapsules.
Nanoarchitectonics for Brain Drug Delivery
This book discusses basics of brain diseases and the role of nanobiotechnology in existing treatment options for neurodegenerative disorders. It begins with an overview of brain diseases and the need for novel drug-delivery approaches. It highlights the current route for the intranasal advanced drug-delivery systems for brain diseases. It also discusses innovative categories of drug-delivery systems, including mesoporous silica nanoparticles, polymeric nanocarriers, and lipid-based nanocarriers through multi-responsive DDSs and their implications in brain disorders. Features: Includes an overview of brain diseases and highlights the need for novel drug-delivery approaches Focuses on theoreti...
Emerging Cognitive Neuroscience and Related Technologies
Emerging Cognitive Neuroscience and Related Technologies, from the National Research Council, identifies and explores several specific research areas that have implications for U.S. national security, and should therefore be monitored consistently by the intelligence community. These areas include: neurophysiological advances in detecting and measuring indicators of psychological states and intentions of individuals the development of drugs or technologies that can alter human physical or cognitive abilities advances in real-time brain imaging breakthroughs in high-performance computing and neuronal modeling that could allow researchers to develop systems which mimic functions of the human b...
Blood-Brain Barrier in Drug Discovery
Focused on central nervous system (CNS) drug discovery efforts, this book educates drug researchers about the blood-brain barrier (BBB) so they can affect important improvements in one of the most significant – and most challenging – areas of drug discovery. • Written by world experts to provide practical solutions to increase brain penetration or minimize CNS side-effects • Reviews state-of-the-art in silico, in vitro, and in vivo tools to assess brain penetration and advanced CNS drug delivery strategies • Covers BBB physiology, medicinal chemistry design principles, free drug hypothesis for the BBB, and transport mechanisms including passive diffusion, uptake/efflux transporters, and receptor-mediated processes • Highlights the advances in modelling BBB pharmacokinetics and dynamics relationships (PK/PD) and physiologically-based pharmacokinetics (PBPK) • Discusses case studies of successful CNS and non-CNS drugs, lessons learned and paths to the market
The Nobel Prizes 2019
The Nobel Prizes is the official yearbook of the Nobel Foundation. This edition provides extensive information about the 2019 laureates: their Nobel Prize lectures and their autobiographies, as well as presentation speeches and background about the Nobel festivities.Published on behalf of the Nobel Foundation.
Video Based Machine Learning for Traffic Intersections
Video Based Machine Learning for Traffic Intersections describes the development of computer vision and machine learning-based applications for Intelligent Transportation Systems (ITS) and the challenges encountered during their deployment. This book presents several novel approaches, including a two-stream convolutional network architecture for vehicle detection, tracking, and near-miss detection; an unsupervised approach to detect near-misses in fisheye intersection videos using a deep learning model combined with a camera calibration and spline-based mapping method; and algorithms that utilize video analysis and signal timing data to accurately detect and categorize events based on the ph...
Advances in Smart Vehicular Technology, Transportation, Communication and Applications
This book highlights papers presented at the Second International Conference on Smart Vehicular Technology, Transportation, Communication and Applications (VTCA 2018), which was held at Mount Emei, Sichuan Province, China from 25 to 28 October 2018. The conference was co-sponsored by Springer, Southwest Jiaotong University, Fujian University of Technology, Chang’an University, Shandong University of Science and Technology, Fujian Provincial Key Lab of Big Data Mining and Applications, and the National Demonstration Center for Experimental Electronic Information and Electrical Technology Education (Fujian University of Technology). The conference was intended as an international forum for researchers and professionals engaged in all areas of smart vehicular technology, vehicular transportation, vehicular communication, and applications.
Advances in Smart Vehicular Technology, Transportation, Communication and Applications
This book highlights papers presented at the Second International Conference on Smart Vehicular Technology, Transportation, Communication and Applications (VTCA 2018), which was held at Mount Emei, Sichuan Province, China from 25 to 28 October 2018. The conference was co-sponsored by Springer, Southwest Jiaotong University, Fujian University of Technology, Chang’an University, Shandong University of Science and Technology, Fujian Provincial Key Lab of Big Data Mining and Applications, and the National Demonstration Center for Experimental Electronic Information and Electrical Technology Education (Fujian University of Technology). The conference was intended as an international forum for researchers and professionals engaged in all areas of smart vehicular technology, vehicular transportation, vehicular communication, and applications.
