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The Clinical and Ethical Practice of Neuromodulation – Deep Brain Stimulation and Beyond
Neuromodulation is among the fastest-growing areas of medicine, involving many diverse specialties and affecting hundreds of thousands of patients with numerous disorders worldwide. It can briefly be described as the science of how electrical, chemical, and mechanical interventions can modulate the nervous system function. A prominent example of neuromodulation is deep brain stimulation (DBS), an intervention that reflects a fundamental shift in the understanding of neurological and psychiatric diseases: namely as resulting from a dysfunctional activity pattern in a defined neuronal network that can be normalized by targeted stimulation. The application of DBS has grown remarkably and more than 130,000 patients worldwide have obtained a DBS intervention in the past 30 years—most of them for treating movement disorders. This Frontiers Research Topics provides an overview on the current discussion beyond basic research in DBS and other brain stimulation technologies. Researchers from various disciplines, who are working on broader clinical, ethical and social issues related to DBS and related neuromodulation technologies, have contributed to this research topic.
Brain Stimulation
- A volume in the Handbook of Clinical Neurology series, which has an unparalleled reputation as the world's most comprehensive source of information in neurology. - International list of contributors including the leading workers in the field. - Describes the advances which have occurred in clinical neurology and the neurosciences, their impact on the understanding of neurological disorders and on patient care. - A volume in the Handbook of Clinical Neurology series, which has an unparalleled reputation as the world's most comprehensive source of information in neurology. - International list of contributors including the leading workers in the field. - Describes the advances which have occurred in clinical neurology and the neurosciences, their impact on the understanding of neurological disorders and on patient care.
Emerging Horizons in Neuromodulation
This issue of International Review of Neurobiology brings together cutting-edge research on neuromodulation. It reviews current knowledge and understanding, provides a starting point for researchers and practitioners entering the field, and builds a platform for further research and discovery. - Brings together cutting-edge research on neuromodulation - Reviews current knowledge and understanding - Provides a starting point for researchers and practitioners entering the field, and builds a platform for further research and discovery
The Hidden Life of the Basal Ganglia
The anatomy and physiology of the basal ganglia and their relation to brain and behavior, disorders and therapies, and philosophy of mind and moral values. The main task of the basal ganglia—a group of subcortical nuclei, located at the base of the brain—is to optimize and execute our automatic behavior. In this book, Hagai Bergman analyzes the anatomy and physiology of the basal ganglia, discussing their relation to brain and behavior, to disorders and therapies, and even to moral values. Drawing on his forty years of studying the basal ganglia, Bergman presents new information on physiology and computational models, Parkinson’s disease and other ganglia-related disorders, and such th...
The Basal Ganglia IX
The aim of the International Basal Ganglia Society (IBAGS) is to further our understanding of normal basal ganglia function and the pathophysiology of disorders of the basal ganglia, including Parkinson's disease, Huntington's disease, and schizophrenia. Each triennial meeting of IBAGS brings together basic research scientists from all disciplines as well as clinicians who are actively involved in the treatment of basal ganglia disorders, to discuss the most recent advances in the field and to generate new approaches and ideas for the future. This volume comprises the proceedings of the 9th meeting of IBAGS, held in Egmond aan Zee, The Netherlands, September 2nd-6th, 2007.
Medical Image Computing and Computer-Assisted Intervention – MICCAI 2007
This title is part of a two-volume set that constitute the refereed proceedings of the 10th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2007. Coverage in this first volume includes diffusion tensor imaging and computing, cardiac imaging and robotics, image segmentation and classification, image guided intervention and robotics, innovative clinical and biological applications, brain atlas computing, and simulation of therapy.
Hormones of the Limbic System
First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines. This volume focuses on hormones of the limbic system. - Longest running series published by Academic Press - Contributions by leading international authorities
Behavioral Neurobiology of Depression and Its Treatment
The book highlights important new research using current state-of-the-art approaches by prominent researchers in the field of depression. A broad range of topics is covered, beginning with a description of the phenotypic features of clinical depression, followed by chapters on the cellular and molecular basis, functional neuroimaging correlates and information-processing accounts. Finally, existing and novel treatment approaches are covered. In this way the volume brings together the key disciplines involved in the neurobiological understanding of depression to provide an update of the field and outlook to the future. Together, the volume chapters provide focused and critical reviews that span a broad range of topics suitable for both students and established investigators interested in the present state of depression research.
Basal ganglia: physiological, behavioral, and computational studies
The basal ganglia has received much attention over the last two decades, as it has been implicated in many neurological and psychiatric disorders. Most of this research—in both animals and humans—attempt to understand the neural and biochemical substrates of basic motor and learning processes, and how these are affected in human patients as well as animal models of brain disorders. The current volume contains research articles and reviews describing basic, pre-clinical and clinical neuroscience research of the basal ganglia written by attendees of the 11th Triennial Meeting of the International Basal Ganglia Society (IBAGS) that was held March 3-7th, 2013 at the Princess Hotel, Eilat, Israel and by researchers of the basal ganglia. Specifically, articles in this volume include research reports on the biochemistry, computational theory, anatomy and physiology of single neurons and functional circuitry of the basal ganglia networks as well as the latest data on animal models of basal ganglia dysfunction and clinical studies in human patients.
