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Opsin-free Optogenetics
  • Language: en
  • Pages: 221

Opsin-free Optogenetics

  • Type: Book
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  • Published: 2022-12-14
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  • Publisher: CRC Press

Optogenetics represents a breakthrough technology capable of dynamically modulating molecular and cellular activity in live cells with high precision. This transformative technology made it possible to reversibly interrogate protein actions, cellular events, and animal behaviors with a simple flash of light. Manipulating the temporal and spatial profile of light enabled precise control of membrane potentials. This feature has inspired non-opsin-based optogenetics, which not only inherits the precise spatiotemporal resolution but also expands the targets into a diverse pool of biomolecules such as membrane receptors, ion channels, kinases, GTPases, and transcription factors. This book is uniq...

Man-Machine-Environment System Engineering
  • Language: en
  • Pages: 711

Man-Machine-Environment System Engineering

Man-Machine-Environment System Engineering: Proceedings of the 23rd Conference on MMESE are an academic showcase of the best papers selected from more than 500 submissions, introducing readers to the top research topics and the latest developmental trends in the theory and application of MMESE. This proceedings are interdisciplinary studies on the concepts and methods of physiology, psychology, system engineering, computer science, environment science, management, education, and other related disciplines. Researchers and professionals who study an interdisciplinary subject crossing above disciplines or researchers on MMESE subject will be mainly benefited from this proceedings. MMESE primari...

International Conference on Transportation
  • Language: en
  • Pages: 462

International Conference on Transportation

The main objectives of 2013 International Conference on Transportation (ICTR2013) are to bring together representatives of transportation engineering , of various institutions, universities, industry and professional associations, to debate and exchange experience on important conference topics. Another main objective of ICTR2013 consists of providing a good networking opportunity to all these groups. The ICTR2013 became a major conference to exchang e new ideas of transportation in Asia researchers and provide a form to present their new results in transportation engineering, vehicle operation engineering, transportation planning, traffic information engineering and control, pavement and br...

Autophagy Regulation of Innate Immunity
  • Language: en
  • Pages: 203

Autophagy Regulation of Innate Immunity

This book discusses novel concepts and discoveries concerning the regulation of innate immunity by autophagy and autophagy-related proteins. In the past decade, there have been major advances in our understanding of the molecular mechanisms of autophagy and its physiological functions. This book highlights emerging studies on the underlying mechanisms of autophagy regulation of innate immunity, including inflammation, antiviral immunity and anti-bacterial responses and the signaling pathways that prompt or inhibit the initiation and progression of related diseases. It also offers new ideas and strategies for future drugs based on manipulating autophagy, especially selective autophagy mediated by cargo receptors. Providing a comprehensive overview of the autophagy regulation of innate immunity, it is a valuable resource for graduate students and researchers in the fields of immunology, cell biology and translational medicine.

Man-Machine-Environment System Engineering: Proceedings of the 21st International Conference on MMESE
  • Language: en
  • Pages: 899

Man-Machine-Environment System Engineering: Proceedings of the 21st International Conference on MMESE

Man-Machine-Environment System Engineering: Proceedings of the 21st Conference on MMESE is the academic showcase of best research papers selected from more than 500 submissions each year. From this book reader will learn the best research topics and the latest development trend in MMESE design theory and other human-centered system application.MMESE focus mainly on the relationship between Man, Machine and Environment. It studies the optimum combination of man-machine-environment systems. In the system, the Man means the working people as the subject in the workplace (e.g. operator, decision-maker); the Machine means the general name of any object controlled by the Man (including tool, Machi...

Proceedings of the 13th International Conference on Man-Machine-Environment System Engineering
  • Language: en
  • Pages: 603

Proceedings of the 13th International Conference on Man-Machine-Environment System Engineering

The integrated and advanced science research topic Man-Machine-Environment system engineering (MMESE) was first established in China by Professor Shengzhao Long in 1981, with direct support from one of the greatest modern Chinese scientists, Xuesen Qian. In a letter to Shengzhao Long from October 22nd, 1993, Xuesen Qian wrote: “You have created a very important modern science and technology in China!” MMESE primarily focuses on the relationship between man, machines and the environment, studying the optimum combination of man-machine-environment systems. In this system, “man” refers to people in the workplace (e.g. operators, decision-makers); “ machine” is the general name for a...

Data Mining and Big Data
  • Language: en
  • Pages: 519

Data Mining and Big Data

​This two-volume set, CCIS 1453 and CCIS 1454, constitutes refereed proceedings of the 6th International Conference on Data Mining and Big Data, DMBD 2021, held in Guangzhou, China, in October 2021. The 57 full papers and 28 short papers presented in this two-volume set were carefully reviewed and selected from 258 submissions. The papers present the latest research on advantages in theories, technologies, and applications in data mining and big data. The volume covers many aspects of data mining and big data as well as intelligent computing methods applied to all fields of computer science, machine learning, data mining and knowledge discovery, data science, etc.

Cancer Immunotherapy
  • Language: en
  • Pages: 313

Cancer Immunotherapy

This volume details multiple areas of new and emerging methods to develop the next generation of immunotherapy treatments. Chapters guide readers through analysis and characterisation of the interactions between tumour and immune cells, and cell engineering tools for cancer treatment, to provide a unique and compelling set of techniques instrumental to work with, and engineer, immune cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Cancer Immunotherapy: Methods and Protocols aims to ensure successful results in the further study of this vital field.

Wireless Algorithms, Systems, and Applications
  • Language: en
  • Pages: 677

Wireless Algorithms, Systems, and Applications

The three-volume set constitutes the proceedings of the 17th International Conference on Wireless Algorithms, Systems, and Applications, WASA 2022, which was held during October 28-30, 2022. The conference took place in Dalian, China.The 95 full and 62 short papers presented in these proceedings were carefully reviewed and selected from 265 submissions. The contributions in ​algorithms, systems; and applications of internet of things;information processing and data management;radar and sonar networks

Taste and Odour in Source and Drinking Water
  • Language: en
  • Pages: 322

Taste and Odour in Source and Drinking Water

This book provides an updated evaluation of the characterization and management of taste and odour (T&O) in source and drinking waters. Authored by international experts from the IWA Specialist Group on Off-flavours in the Aquatic Environment, the book represents an important resource that synthesizes current knowledge on the origins, mitigation, and management of aquatic T&O problems. The material provides new knowledge for an increasing widespread degradation of source waters and global demand for high quality potable water. Key topics include early warning, detection and source-tracking, chemical, sensory and molecular diagnosis, treatment options for common odorants and minerals, source ...