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Microbiome in Gastrointestinal Cancer
This book covers state-of-the-art topics covering evidences indicate that the gut microbiota can be harnessed for cancer prevention as well as to modulate the efficacy of chemotherapy and immunotherapy. This book includes: 1) characterization of the dysregulated microbiome in gastrointestinal cancers (Chapters 1-6); 2) the molecular mechanism of action of gut microbiota via microbial metabolites and direct interaction with host cancer or immune cells (Chapters 7-11); 3) key methodologies for studying the role of gut microbiota in cancers (Chapters 12-13); and 4) the potential application of gut microbes for the prevention and treatment of gastrointestinal cancers (Chapters 14-17). The contributors are international experts in molecular and cellular biology, microbiology, metabolomics, bioinformatics and physician scientists to provide in-depth reviews of this subject. This book provides a rich resource of information on this important topic for graduate students, basic researchers and physicians.
Human Microbiome in Health, Disease, and Therapy
This book illustrates the role of the human microbiome in health and diseases. It discusses the association of an imbalanced human microbiome with different human diseases, including inflammatory, metabolic conditions, neurological, cardiovascular, and respiratory diseases. The book further reviews the association between intestinal microbiota and immune defense systems. The book provides evolving knowledge of the development, complexity, and functionality of the healthy gut microbiota and covers interventions that modulate and stabilize the gut microbiota. Further, it introduces the human microbiome as a reservoir of AMR genes, the current knowledge on the resistome, and the recent and upco...
Sinophone Southeast Asia
"This volume explores the diverse linguistic landscape of Southeast Asia's Chinese communities. Based on archival research and previously unpublished linguistic fieldwork, it unearths a wide variety of language histories, linguistic practices, and trajectories of words. The localized and often marginalized voices we bring to the spotlight are quickly disappearing in the wake of standardization and homogenization, yet they tell a story that is uniquely Southeast Asian in its rich hybridity. Our comparative scope and focus on language, analysed in tandem with history and culture, adds a refreshing dimension to the broader field of Sino-Southeast Asian Studies"--
LTE - The UMTS Long Term Evolution
"Where this book is exceptional is that the reader will not just learn how LTE works but why it works" Adrian Scrase, ETSI Vice-President, International Partnership Projects Following on the success of the first edition, this book is fully updated, covering the latest additions to LTE and the key features of LTE-Advanced. This book builds on the success of its predecessor, offering the same comprehensive system-level understanding built on explanations of the underlying theory, now expanded to include complete coverage of Release 9 and the developing specifications for LTE-Advanced. The book is a collaborative effort of more than 40 key experts representing over 20 companies actively partici...
Teaching Chinese as a Second Language
Grounded in analysis of Chinese and international educational concepts and classroom techniques currently used to teach Chinese as a Second Language, and a thorough review of recent research in the field, this volume identifies the learning challenges of the language for native English speakers. Orton and Scrimgeour assess the gap in knowledge and skills between learners’ initial and future proficiency levels as L2 Chinese speakers, map their needs as learners towards achieving a high language proficiency, and set out an informed, integrated teaching orientation and practice for the Chinese classroom that responds to those needs. Chapters in the volume address curriculum design, teaching diverse learners and levels, the learning challenges of Chinese oral and literacy skills, grammar and vocabulary, discourse development, cultural understanding, and the affordances of a visit to China. Filled with original and engaging teaching and learning tools and techniques, this book is an essential and rich content resource for primary and secondary teachers, and teacher candidates and educators in Chinese as a Second Language education.
Once Upon a Time in China
From Jackie Chan to Ang Lee, from "Supercop" to "Crouching Tiger, Hidden Dragon," Chinese cinema has truly arrived in the U.S. Filled with photos and tidbits, this is the definitive book for anyone who has already fallen in love with Chinese cinema--and all those who are looking to learn more about it.
Immune Regulations of Inflammatory Skin Diseases
Skin is our primary interface with the environment, and T cells are crucial for orchestrating host immune responses against pathogenic microorganisms. Dysregulated immune responses, on the other hand, can result in chronic inflammatory skin diseases. The complex regulatory networks include effector T cells, memory T cells, regulatory T cells, immunoregulatory co-signaling molecules and cytokines that control skin immunity, and the mechanisms that regulate skin immune responses in host defense and in immune-mediated cutaneous diseases. The immune-regulatory networks are involved in the common inflammatory skin diseases, including psoriasis, atopic dermatitis, alopecia areata, vitiligo, bullous diseases, and cutaneous adverse drug reaction. The goal of this Research Topic is to provide a forum to advance research on the contribution of skin inflammation to the genesis and development of the skin diseases as well as to explore innovative skin-oriented pharmacological interventions, mainly on the immune regulatory networks, in the attempt to achieve a beneficial impact on the skin disease course.
Education-at-large: Student Life And Activities In Singapore 1945-1965
The first part of the book contains documentation of a groundbreaking exhibition held in 2007 on student activities and societal engagements during post-war Singapore 1945-1965 and transcripts of forums held in conjunction with it. The second half centres on oral history accounts of mostly former Chinese school students who shared about their social, cultural and political activities in complex but exciting times.Education-at-large broadens our understanding of Singapore's educational history in the transitional period between the end of the Second World War and the country's independence; examines the ways in which student activities and activism resonated with, and contributed to, the country's wider social, political and cultural life, as well as the decolonisation process; and stimulates debates about Chinese education and student activism in Singapore.
