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Sapporo, Otaru & Niseko Travel Guide
One of Japan’s most dynamic and newest cities, Sapporo is a spacious and laid-back place than you can imagine, with a number of fabulous parks, modern buildings, shopping malls, ski areas, dining and drinking options. It is a perfect place to explore if this is your first time in Hokkaido. As you leave the megacity of Sapporo, Central Hokkaido (simply called Dō-ō) is such a good distillation of all Hokkaido highlights that can be visited in a few days. It is an easily explored region on a short schedule and you can accessible a wide range of must-sees by public transport. The nostalgic port town of Otaru is the best destination from Sapporo if your time is limited. Japan’s most cosmo...
Advanced Oxidation Processes for Micropollutant Remediation
Advanced Oxidation Processes for Micropollutant Remediation covers current state-of-the-art in advanced oxidation processes (AOP) for removal of micropollutants from industrial and pharmaceutical wastewater. It covers various AOP-based techniques like Fenton process, ozonation, hydrogen peroxide, ultraviolet radiation, electrochemical oxidation, ultrasonic irradiation, and other hybrid technologies. It focuses on aspects like impact of micropollutants on the ecosystems, different types of AOPs, their principles, applications, and challenges in implementing these techniques and their future perspectives. Features: Presents state-of-the-art in advanced oxidation processes (AOP) techniques alon...
Drug Metabolism, Pharmacokinetics and Bioanalysis
Drug metabolism/pharmacokinetics and drug interaction studies have been extensively carried out in order to secure the druggability and safety of new chemical entities throughout the development of new drugs. Recently, drug metabolism and transport by phase II drug metabolizing enzymes and drug transporters, respectively, as well as phase I drug metabolizing enzymes, have been studied. A combination of biochemical advances in the function and regulation of drug metabolizing enzymes and automated analytical technologies are revolutionizing drug metabolism research. There are also potential drug–drug interactions with co-administered drugs due to inhibition and/or induction of drug metabolic enzymes and drug transporters. In addition, drug interaction studies have been actively performed to develop substrate cocktails that do not interfere with each other and a simultaneous analytical method of substrate drugs and their metabolites using a tandem mass spectrometer. This Special Issue has the aim of highlighting current progress in drug metabolism/pharmacokinetics, drug interactions, and bioanalysis.
Back Running
“It’s 2025, and a tech war between the U.S., Russia and China has culminated in the collapse of power grids across the world with technology becoming obsolete.” A young high school football coach and his family watch helplessly as their power grid goes down — with no warning. They can’t access their bank to get any money, they can’t call the police when they hear people breaking into houses in their neighborhood. They can’t buy gas for their generator and as they’re cleaning out what’s left to eat in the refrigerator, Coach comes up with a plan. His father had left him a cabin in the woods in South Carolina. They could go there and get away from the looting to survive by hunting and fishing. There were fruit trees on the property and they had planted blackberry bushes a couple years ago that should be producing by now. Little did they know how soon foreign powers would have them in their cross hairs and would do anything to steal their secret.”
Natural Organic Matter in Water
Natural Organic Matter in Water: Characterization, Treatment Methods, and Climate Change Impact, Second Edition focuses on advanced filtration and treatment options, as well as processes for reducing disinfection by-products, making it an essential resource on the latest breakthroughs in the characterization, treatment and removal of natural organic matter (NOM) from drinking water. Based on the editor’s years of research and field experience, the book covers general parameters, isolation and concentration, fractionation, composition and structural analysis, and biological testing, along with removal methods such as inorganic coagulants, polyelectrolytes and composite coagulants. In additi...
Foreign Direct Investment in Latin America and the Caribbean 2019
This ECLAC annual report sets out and analyses the main foreign direct investment (FDI) trends in the countries of Latin America and the Caribbean. In the region, FDI inflows were up (by 13.2%) year on year for the first time in five years, at US$ 184.287 billion. This performance is explained by higher flows into just a few countries, however, mainly Brazil and Mexico. Moreover, it does not reflect equity investment, but higher inflows in the form of intercompany loans and, to a lesser extent, reinvestment of earnings. Manufactures and services were the sectors receiving most equity, although there was a slight rise in investment in natural resource sectors compared with 2018.
Programming Languages and Systems
This book constitutes the refereed proceedings of the 10th Asian Symposium on Programming Languages and Systems, APLAS 2012, held in Kyoto, Japan, in December 2012. The 24 revised full papers presented together with the abstracts of 3 invited talks were carefully reviewed and selected from 58 submissions. The papers are organized in topical sections on concurrency, security, static analysis, language design, dynamic analysis, complexity and semantics, and program logics and verification.
Combinatorial Optimization and Applications
The conference proceeding LNCS 11346 constitutes the refereed proceedings of the 12th International Conference on Combinatorial Optimization and Applications, COCOA 2018, held in Atlanta, GA, USA, in December 2018. The 50 full papers presented were carefully reviewed and selected from 106 submissions. The papers cover most aspects of t graph algorithms, routing and network design problems, scheduling algorithms, network optimization, combinatorial algorithms, approximation algorithms, paths and connectivity problems and much more.
Occurrence, Distribution and Toxic Effects of Emerging Contaminantsx
Emerging contaminants include an extensive array of synthetic chemicals in global use, such as plastic additives, microplastics, water disinfection byproducts, pharmaceuticals, man-made nanomaterials, and UV-filters. Because of their extensive use in anthropogenic activities, these chemicals are entering the environment at alarming levels as hazardous wastes and non-biodegradable substances. This book emphasizes on the comprehensive information on emerging contaminants overview, environmental occurrence, analysis, risk assessment and toxicity assessment. Environmental, legal, health concerns of the ECs have also been covered in this book. The book also features an updated status from the industrial point of view.
