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Biological Insights of Multi-Omics Technologies in Human Diseases
"Biological Insights of Multi-Omics Technologies in Human Diseases ́ provides detailed information about the basics of multi-omic technologies including ethics, historical perspective, science, drug discovery, and development and metabolism. With a strong focus on the practical application of omics approaches in cancer, cardiovascular, neurology, respiratory, viral, gastroenterology, autoimmune diseases, PCOS and tuberculosis, this book also includes special topics related to COVID-19 and Machine learning approaches. In 13 chapters this book provides comprehensive coverage of the challenges and opportunities facing the therapeutic implications of multi-omics from academic, regulatory, pharm...
Pharmacogenomics
Pharmacogenomics: From Discovery to Clinical Implementation is a complete reference aimed at building a solid foundation of the key concepts in this fast-moving knowledge area. The editors lined up a group of worldwide experts to contribute to the book. Following a consistent chapter structure, the authors cover the foundational aspects of pharmacogenomics in the first four chapters of the book that include basic concepts, drug metabolism, drug discovery and development, and testing. The second part of the book is dedicated to detailed studies of key health conditions and the potential therapeutic applications of pharmacogenomics. Diseases covered include diabetes, cardiovascular diseases, p...
Ethnopharmacological Investigation of Indian Spices
Though their usage greatly diminished at the dawn of the scientific area, Indian spices were traditional parts of healthcare for thousands of years. However, over the last decade, largely due to the growth in popularity of complementary and alternative medicine, spices have regained attention due to their physiological and functional benefits. By applying modern research methods to traditional remedies, it is possible to discover what made these spices such effective ailment treatments. Ethnopharmacological Investigation of Indian Spices is a collection of innovative research that analyzes the chemical properties and medical benefits of Indian spices in order to design new therapeutic drugs ...
Genetic Polymorphism and Disease
Genetic polymorphisms are important determinants of phenotypic variations and may modulate the risk to or even cause various diseases including genetic disorders and multifactorial diseases. Genetic polymorphisms also serve as important genetic, population and evolutionary markers that allow the study of genetic and evolutionary aspects of individuals, populations and organisms and aid in tracing the evolutionary and parental lineages. Genetic polymorphisms in low penetrance genes are responsible for the alterations in the gene expression of critical signal transduction proteins and metabolic enzymes. Some of these polymorphisms are linked to increased susceptibility to various diseases espe...
Antioxidants in Fruits: Properties and Health Benefits
This book provides a comprehensive review of the antioxidant value of widely consumed fruits. Each chapter covers the botanical description, nutritional & health properties of these popular fruits. Fruits are one of the most important indicators of dietary quality and offer protective effects against several chronic diseases such as cardiovascular diseases, obesity, and various types of cancer. In order to effectively promote fruit consumption, it is necessary to know and understand the components of fruits. In addition to underscoring the importance of fruit consumption’s effects on human diet, the book addresses the characterization of the chemical compounds that are responsible for the antioxidant proprieties of various fruits. Given its scope, the book will be of interest to graduate and post-graduate students, research scholars, academics, pomologists and agricultural scientists alike. Those working in various fruit processing industries and other horticultural departments will also find the comprehensive information relevant to their work.
Spectrum and Power Allocation in Cognitive Radio Systems
As wireless services rapidly expand, the inefficient use of limited spectrum resources poses a critical challenge. The conventional approach to spectrum allocation, based on fixed assignments, could be more effective in meeting the escalating demand for wireless devices and systems. Cognitive radio technology offers a transformative solution by reimagining the spectrum as a multidimensional space, enabling opportunistic access to underutilized bands. However, the field of cognitive radio is still in its early stages, needing more in-depth analyses and descriptions of crucial processes. Spectrum and Power Allocation in Cognitive Radio Systems addresses this pressing need by offering a comprehensive guide for academic scholars, researchers, and industry professionals. This book delves into cognitive radio technology's foundations, organization, and challenges, providing insights into dynamic spectrum access, networking protocols, hardware architecture, and emerging applications. It presents advanced topics such as spectrum sensing algorithms, cooperative spectrum sensing, and multi-user access, offering practical solutions to enhance spectrum efficiency.
Pesticide Toxicology and Risk Assessment
With the emergence of new pesticide combinations and application methods, assessing their potential risks to non-target organisms and human well-being becomes paramount. Pesticide Toxicology and Risk Assessment focuses on the need and strategies for safe and efficient use of pesticides. It offers insights from toxicogenomics, enabling an understanding of the genetic and epigenetic factors influencing human susceptibility to chemical toxicity, thereby quantifying their impacts. This book underscores the significance of risk assessment methodologies considering real-time variables influencing pesticide exposure to the environment and humans. It provides comprehensive details about models desig...
Plant Micronutrients
Plants require essential nutrients (macronutrients and micronutrients) for normal functioning. Sufficiency range is the levels of nutrients necessary to meet the plant’s needs for optimal growth. This range depends on individual plant species and the particular nutrient. Nutrient levels outside of a plant’s sufficiency range cause overall crop growth and health to decline, due either to deficiency or toxicity from over-accumulation. Apart from micronutrients (B, Cl, Mn, Fe, Zn, Cu and Mo), Aluminum (Al), cerium (Ce), cobalt (Co), iodine (I), lanthanum (La), sodium (Na), selenium (Se), silicon (Si), titanium (Ti), and vanadium (V) are emerging as novel biostimulants that may enhance crop ...
Human Organs-on-a-Chip Technology
Human Organs-on-a-Chip Technology focuses on the technology advancement from "organ-on-a-chip to "multi organs-on-a-chip to the newest stage of "human organs-on-a-chip. Chapters investigate the design, simulation studies, device development and application of microfluidic systems. They also offer expert perspectives on the development of an alternative test system in the biological evaluation of drugs, cosmetics, chemicals, medical devices and many others. Lastly, the book addresses issues related to the development of microfluidic devices and alternative test systems in biological and biomedical research. - Explores organs-on-a-chip technology, from the basics, to advanced developments and existing challenges and recent research trends and applications - Reviews every aspect of microfluidic devices, including biological evaluation and targeted delivery - Includes the latest information on regulatory updates
Therapeutic Applications of Honey and its Phytochemicals
Honey typically has a complex chemical and biochemical composition that invariably includes complex sugars, specific proteins, amino acids, phenols, vitamins, and rare minerals. It is reported to be beneficial in the treatment of various diseases, such as those affecting the respiratory, cardiovascular, gastrointestinal, and nervous systems, as well as diabetes mellitus and certain types of cancers; however, there is limited literature describing the use of honey in modern medicine. This book provides evidence-based information on the pharmaceutical potential of honey along with its therapeutic applications and precise mechanisms of action. It discusses in detail the phytochemistry and pharmacological properties of honey, highlighting the economic and culturally significant medicinal uses of honey and comprehensively reviewing the scientific research on the traditional uses, chemical composition, scientific validation, and general pharmacognostical characteristics. Given its scope, it is a valuable tool for researchers and scientists interested in drug discovery and the chemistry and pharmacology of honey.
