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Insights in Neuro-Oncology and Neurosurgical Oncology: 2021
We are now entering the third decade of the 21st Century, and, especially in the last years, the achievements made by scientists have been exceptional, leading to major advancements in the fast-growing field of Oncology. Frontiers has organized a series of Research Topics to highlight the latest advancements in research across the field of Oncology, with articles from the Associate Members of our accomplished Editorial Boards. This editorial initiative of particular relevance, led by Prof. David Eisenstat, Specialty Chief Editor of the Neuro-Oncology and Neurosurgical Oncology section, together with Prof. Erik Sulman, focused on new insights, novel developments, current challenges, latest di...
Dexamethasone Treatment Limits Efficacy of Radiation, But Does Not Interfere with Glioma Cell Death Induced by Tumor Treating Fields
Background: Dexamethasone (Dex) is the most common corticosteroid to treat edema in glioblastoma (GBM) patients. Recent studies identified the addition of Dex to radiation therapy (RT) to be associated with poor survival. Independently, Tumor Treating Fields (TTFields) provides a novel anti-cancer modality for patients with primary and recurrent GBM. Whether Dex influences the efficacy of TTFields, however, remains elusive. Methods: Human GBM cell lines MZ54 and U251 were treated with RT or TTFields in combination with Dex and the effects on cell counts and cell death were determined via flow cytometry. We further performed a retrospective analysis of GBM patients with TTFields treatment +/-...
Mississippi
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If
Amy Carmichael questions whether we allow our doubts and disappointments to hinder our faith, or do we really know Calvary’s love? In a series of statements and common situations, a Christ-love of forgiveness and strength is meant to mend our hearts and encourage others, because of what He has already done.
Changing White Attitudes toward Black Political Leadership
Despite the hopes of the civil rights movement, researchers have found that the election of African Americans to office has not greatly improved the well-being of the black community. By shifting the focus to the white community, this book shows that black representation can have a profound impact. Utilizing national public opinion surveys, data on voting patterns in large American cities, and in-depth studies of Los Angeles and Chicago, Zoltan Hajnal demonstrates that under most black mayors there is real, positive change in the white vote and in the racial attitudes of white residents. This change occurs because black incumbency provides concrete information that disproves the fears and expectations of many white residents. These findings not only highlight the importance of black representation; they also demonstrate the critical role that information can play in racial politics to the point where black representation can profoundly alter white views and white votes.
The Los Angeles Central Library
In the most comprehensive investigation of the Los Angeles Public Library’s early history and architectural genesis ever undertaken, Kenneth Breisch chronicles the institution’s first six decades, from its founding as a private library association in 1872 through the completion of the iconic Central Library building in 1933. During this time, the library evolved from an elite organization ensconced in two rooms in downtown LA into one of the largest public library systems in the United States—with architect Bertram Grosvenor Goodhue’s building, a beloved LA landmark, as its centerpiece. Goodhue developed a new style, fully integrating the building’s sculptural and epigraphic progra...
Carrie Catt
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