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Autoimmune Hemolytic Anemia (AIHA)
Hemolytic anemia is a clinical condition where red blood cell (RBC) destruction exceeds the ability of the body to supply new ones. In immunohemolytic anemia, the causes of the destruction are antibodies against RBC antigens. These antibodies may be either alloantibodies (isoantibodies), transfused or transferred across the placenta (e.g., in hemolytic anemia of the newborn), or autoantibodies (in AIHA). Once formed, these antibodies bind to the surface of RBCs, marking them for destruction in the blood vessels (intravascular hemolysis) and/or for elimination by phagocytosis by macrophages in the reticulo-endothelial system (extravascular hemolysis). This book presents current research on the symptoms, diagnosis and treatment of AIHA. Chapter One examines oxidative stress in AIHA. Chapter Two discusses AIHA in primary immunodeficiency disorders, while Chapter Three studies AIHA in cancer disorders. Chapter Four reviews AIHA post solid organ transplants. The final chapter reviews the incidence, possible pathophysiology, clinical presentations, management strategies and challenges and outcome after an allogeneic hematopoietic stem cell transplant.
Case Studies in Immunology: Autoimmune Hemolytic Anemia
This case study is about an autoimmune disease triggered by infection. It describes how Gwendolen Fairfax, a healthy, unmarried 34-year-old bank manager, who developed the sudden onset of fever, cough and anemia, was started on erythromycin by intravenous administration for treatment.
Field Guide for the Determination of Biological Contaminants in Environmental Samples
This second edition of AIHA's Field Guide incorporates the most recent findings and research that reflect prevailing occupational health and safety and industrial hygiene practices. Its nine chapters provide the most current solutions to problems facing professionals working with biological contaminants. This guide serves as an academic and professional reference.
ANSI/AIHA Z9.2-2006 Fundamentals Governing the Design and Operation of Local Exhaust Ventilation Systems
This new standard describes fundamental good practices related to the commissioning, design, selection, installation, operation, maintenance, and testing of local exhaust ventilation (LEV) systems used for the control of employee exposure to airborne contaminants.
Complement-mediated Hemolytic Anemias, An Issue of Hematology/Oncology Clinics of North America,
This issue of Hematology/Oncology Clinics of North America, guest edted by Dr. Robert Brodsky, is devoted to Complement-mediated Hemolytic Anemias. Articles in this outstanding issue include: Complement: An overview for the clinician; Warm autoimmune hemolytic anemia; Cold Agglutinin Disease; ABO incompatible blood transfusions; Paroxysmal cold hemoglobinuria; Paroxysmal nocturnal hemoglobinuria; Congenital CD59 deficiency; Atypical Hemolytic Uremic Syndrome (HUS); Typical Hemolytic Uremic Syndrome (HUS); Thrombotic thrombocytopenic purpura; and Pharmacologic complement inhibitors.
New Developments in the Understanding and Treatment of Autoimmune Hemolytic Anemia, an Issue of Hematology/Oncology Clinics of North America, 36
In this issue of Hematology/Oncology Clinics, guest editors Drs. Alexandra P. Wolanskyj-Spinner and Ronald S. Go bring their considerable expertise to the topic of New Developments in the Understanding and Treatment of Autoimmune Hemolytic Anemia. Top experts in the field cover key topics such as warm AIHA; cold AIHA; drug-induced AIHA; adult Evans syndrome; immunotherapy-associated AIHA; complications of AIHA; and more. Contains 11 relevant, practice-oriented topics including diagnosis and differential diagnosis; red cell antigens and antibodies; traditional and novel tests; DAT neg AIHA; and more. Provides in-depth clinical reviews on new developments in the understanding and treatment of autoimmune hemolytic anemia, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
