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We believe that the role of glia is the next frontier to be explored in Alzheimer’s disease research. This eBook is an update on both the current knowledge of astrocytes and microglia involvement in Alzheimer’s disease pathophysiology, and some of the techniques available to study them.
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Revisión práctica y actual sobre el diagnóstico, manejo y tratamiento de la Enfermedad de Alzheimer. Asimismo, se estudia desde el deterioro congnitivo leve a la valoración de la conducción en pacientes con deterioro cognitivo, pasando por la utilidad del estudio neuropsicológico, los marcadores biológicos y de neuroimagen, la indicación del estudio genético, el tratamiento de los síntomas congnitivos y conductuales, la asociación con la demencia vascular y la importancia de la comorbolidad en la enfermedad. Concluye con las recomendaciones de la Sociedad Española de Neurología para la práctica clínica en el diagnóstico y tratamiento del deterioro cognitivo leve y la enfermedad.
Alzheimer disease (AD) is a neurodegenerative disorder characterized by significant cognitive deficits, behavioral changes, sleep disorders and loss of functional autonomy. AD represents the main cause of dementia and has become a major public health issue. In addition, the number of patients suffering from AD is growing rapidly as the population ages worldwide. Memory impairment is usually the earliest clinical and core symptom of this disease. The diagnosis at a late clinical stage is relatively easy. However, a delay in the diagnosis is damageable for the handling of patients in terms of optimal medical and social care. The actual interest of the scientific head-ways is to optimize the di...
This pocketbook summarises the latest understanding of the possible causes of the disease, the methods of diagnosis and assessment, and current management techniques.