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Coronavirus disease 2019 (COVID-19), produces the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), with atypical pneumonia. This infection is a global health challenge producing post-acute sequelae of SARS-CoV-2 infection (PASC), including neuro-PASC in which direct or indirect invasion of the virus into the brain causes immune dysregulation, hormonal disorders, elevated cytokine levels due to immune reaction and chronic inflammation, direct tissue injury, and persistent low-grade infection. The COVID-19 induced-neuroinflammation promotes blood-brain barrier (BBB) disruption, access of antigens and inflammatory factors into the brain, as well as infection or immune-mediated resp...
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Following two outcasts' tumultuous friendship, this brilliant novel captures the probing, passionate nature of a generation of global citizens, exploring sexuality and identity. Claudia enters Francesco’s life on a sunny morning, in the school’s entrance hall: it’s a bolt of lightning, the birth of an entirely new kind of desire, which is, above all, the desire for life. Claudia is peerless and self-assured, extravagant; Francesco is introverted, burning with erotic curiosity, dominated by rustic faith, uncertain. She provokes him: “Did you know that your mother and my father were lovers?” But, in the eyes of that meek boy, she glimpses a spark of diversity, she sees herself in him...