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Atlantic Loyalties
Integrating social, cultural, economic, and political history, this is a study of the factors that grounded—or swayed—the loyalties of non-Spaniards living under Spanish rule on the southern frontier. In particular, Andrew McMichael looks at the colonial Spanish administration’s attitude toward resident Americans. The Spanish borderlands systems of slavery and land ownership, McMichael shows, used an efficient system of land distribution and government patronage that engendered loyalty and withstood a series of conflicts that tested, but did not shatter, residents’ allegiance. McMichael focuses on the Baton Rouge district of Spanish West Florida from 1785 through 1810, analyzing why ...
Lymphocytes
Cellular immunology is a rapidly moving field in which recent advances have made significant contributions to our understanding of the immune response to infection and malignancy. These in turn, have given rise to new therapeutic opportunities in areas such as vaccines and immunotheraphy. Many investigators have been discourages by the complicated protocols involved in cellular immunological studies, as illustrated, by the meticulous care required for the generation of antigen-specific T-cells. Lymphocytes: A Practical Approach (second edition) contains straight-forward protocols for well- established procedures in the study of lymphocytes including preparation and identification of lymphocytes, immortalization, cell and organ culture, and quantification assays. It also covers the recent technological advances which have revolutionised the field, such as the use of the Interferon-gamma ELISpot assay and peptide-HLA tetrameric assays to quantify antigen-specifidc T-cells directly from peripheral blood, without the need for in vitro culture, and molecular methods for accurate HLA typing.
Regulation of Immune Gene Expression
This book encompasses the proceedings of a conference held at Trinity College, Oxford on September 21-25, 1985 organized by a committee comprised of Drs. M. Crumpton, M. Feldmann, A. McMichael, and E. Simpson, and advised by many friends and colleagues. The immune response gene workshops that took place were based on the need to understand why certain experimental animal strains were high responders and others were low responders. It was assumed that identification of the immune response (Ir) genes and definition of their products would explain high and low responder status. Research in the ensuing years has identified the Ir gene products involved in antibody responses as the la antigens, o...
Inquiry-Based Lessons in World History, Grades 7-10
Spanning the time period from 750 CE to the present day, Inquiry-Based Lessons in World History (Vol. 2) focuses on creating global connections between people and places using primary sources in standards-based lessons. With sections on the world in transition, the era of revolutions, imperialism and global war, and the modern world, this book provides teachers with inquiry-based, ready-to-use lessons that can be adapted to any classroom and that encourage students to take part in the learning process by reading and thinking like historians. Each section contains chapters that correspond to the scope and sequence of most world history textbooks. Each inquiry lesson begins with an essential question and connections to content and literacy standards, followed by primary source excerpts or links to those sources. Lessons include step-by-step directions, incorporate a variety of literacy strategies, and require students to make a hypothesis using evidence from the texts they have read. Grades 7-10
Inquiry-Based Lessons in World History (Volume 1)
Spanning the time period from 15,000 BCE to 1500 CE, Inquiry-Based Lessons in World History (Vol. 1) focuses on creating global connections between people and places using primary sources in standards-based lessons. With sections on early humans, the ancient world, classical antiquity, and the world in transition, this book provides teachers with inquiry-based, ready-to-use lessons that can be adapted to any classroom and that encourage students to take part in the learning process by reading and thinking like historians. Each section contains chapters that correspond to the scope and sequence of most world history textbooks. Each inquiry lesson begins with an essential question and connections to content and literacy standards, followed by primary source excerpts or links to those sources. Lessons include step-by-step directions, incorporate a variety of literacy strategies, and require students to make a hypothesis using evidence from the texts they have read. Grades 7-10
Leucocyte Typing III
The third international workshop on leucocyte typing antigens reports the results of collaborative experiments involving over 800 antibodies. This volume contains the first and only complete account of the experiments and the subsequent analyses, which produced a careful description of fifty human leucocyte antigens, twenty-four of them fully characterized for the first time. Antigens specific for or shared by T-Cells, B-Cells, activated lymphocytes, myeloid cells and platelets are featured. The papers detail their distribution, molecular structure and function, and discuss the role that the antigens may play in investigating and understanding pathological processes, particularly in leukemias and lymphomas.
Inquiry-Based Lessons in World History
Spanning the time period from 750 CE to the present day, Inquiry-Based Lessons in World History (Vol. 2) focuses on creating global connections between people and places using primary sources in standards-based lessons. With sections on the world in transition, the era of revolutions, imperialism and global war, and the modern world, this book provides teachers with inquiry-based, ready-to-use lessons that can be adapted to any classroom and that encourage students to take part in the learning process by reading and thinking like historians. Each section contains chapters that correspond to the scope and sequence of most world history textbooks. Each inquiry lesson begins with an essential question and connections to content and literacy standards, followed by primary source excerpts or links to those sources. Lessons include step-by-step directions, incorporate a variety of literacy strategies, and require students to make a hypothesis using evidence from the texts they have read. Grades 7-10
A Companion to the Era of Andrew Jackson
A COMPANION TO THE ERA OF ANDREW JACKSON More than perhaps any other president, Andrew Jackson’s story mirrored that of the United States; from his childhood during the American Revolution, through his military actions against both Native Americans and Great Britain, and continuing into his career in politics. As president, Jackson attacked the Bank of the United States, railed against disunion in South Carolina, defended the honor of Peggy Eaton, and founded the Democratic Party. In doing so, Andrew Jackson was not only an eyewitness to some of the seminal events of the Early American Republic; he produced an indelible mark on the nation’s political, economic, and cultural history. A Companion to the Era of Andrew Jackson features a collection of more than 30 original essays by leading scholars and historians that consider various aspects of the life, times, and legacy of the seventh president of the United States. Topics explored include life in the Early American Republic; issues of race, religion, and culture; the rise of the Democratic Party; Native American removal events; the Panic of 1837; the birth of women’s suffrage, and more.
