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Extracellular Vesicles in Health and Disease
Interest in the role of extracellular vesicles (microvesicles and exosomes) is expanding rapidly. It is now apparent that far from being merely cellular debris, these vesicles play a key role in cell-to-cell communication and signaling. Moreover, they are significantly elevated in a number of diseases. This raises the question of their direct role in pathogenesis as well as their possible use as biomarkers. This book stems from the first international meeting on "Microvesicles and Nanovesicles in Health and Disease" held at Magdalen College, Oxford, in 2010. The purpose of the meeting was to bring together, for the first time, a range of experts from around the world to discuss the latest advances in this field. Key to the study of these vesicles is the availability of methodologies for their measurement in biological fluids. A major section of the meeting focused on a range of exciting new technologies which have been developed for this purpose. The presentations at this meeting form the basis of this book, which will appeal to basic scientists, clinicians, and those developing technology for the measurement of extracellular vesicles.
Harmony Search Algorithm
This book presents state-of-the-art technical contributions based around one of the most successful evolutionary optimization algorithms published to date: Harmony Search. Contributions span from novel technical derivations of this algorithm to applications in the broad fields of civil engineering, energy, transportation & mobility and health, among many others and focus not only on its cross-domain applicability, but also on its core evolutionary operators, including elements inspired from other meta-heuristics. The global scientific community is witnessing an upsurge in groundbreaking, new advances in all areas of computational intelligence, with a particular flurry of research focusing on...
Spanish Fever
Fantagraphics Books is proud to introduce American readers to more than 30 artists working on the cutting edge of the form. Spanish Fever is an anthology showcasing the best of the new wave of art comics from a country with one of the strongest cartoon traditions in Europe. It includes the work of masters of the form such as Paco Roca, Miguel Gallardo, David Rubín and Miguel Ángel Martín as well as newcomers like José Domingo, Anna Galvan, Álvaro Ortiz and Sergi Puyol.
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Hyperborder
Roving vigilantes, fear-mongering politicians, hysterical pundits, and the looming shadow of a seven hundred-mile-long fence: the US–Mexican border is one of the most complex and dynamic areas on the planet today. Hyperborder provides the most nuanced portrait yet of this dynamic region. Author Fernando Romero presents a multidisciplinary perspective informed by interviews with numerous academics, researchers, and organizations. Provocatively designed in the style of other kinetic large-scale studies like Rem Koolhaas's Content and Bruce Mau’s Massive Change, Hyperborder is an exhaustively researched report from the front lines of the border debate.
Resúmenes de proyectos de investigación financiados con cargo al programa sectorial general del conocimiento. Año 1995
Informe sobre los proyectos financiados por el Plan Nacional de Investigación Científica y Desarrollo Tecnológico.
Chronicle of a Death Foretold
Chronicle of a Death Foretold is a compelling, moving story exploring injustice and mob hysteria by the Nobel Laureate Gabriel García Márquez, author of One Hundred Years of Solitude and Love in the Time of Cholera. 'On the day they were going to kill him, Santiago Nasar got up at five-thirty in the morning to wait for the boat the bishop was coming on' Santiago Nasar is brutally murdered in a small town by two brothers. All the townspeople knew it was going to happen - including the victim. But nobody did anything to prevent the killing. Twenty seven years later, a man arrives in town to try and piece together the truth from the contradictory testimonies of the townsfolk. To at last understand what happened to Santiago, and why. . . 'A masterpiece' Evening Standard 'A work of high explosiveness - the proper stuff of Nobel prizes. An exceptional novel' The Times 'Brilliant writer, brilliant book' Guardian
