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Targeted Protein Degradation
This volume contains a collection of innovative techniques for studying targeted protein degradation. Chapters guide readers through heterobifunctional proteolysis-targeting chimeras (PROTACs) approaches, E3 ligase, E3 ligase-induced ubiquitylation, proteomic approaches, novel degrader molecules, molecular glue, and stabilize binding interaction between a target and E3 ubiquitin ligase. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Targeted Protein Degradation: Methods and Protocols aims to ensure successful results in this emerging field of drug discovery.
Drug Discovery Handbook
The Drug Discovery Handbook gives professionals a tool to facilitate drug discovery by bringing together, for the first time in one resource, a compendium of methods and techniques that need to be considered when developing new drugs. This comprehensive, practical guide presents an explanation of the latest techniques and methods in drug discovery, including: Genomics, proteomics, high-throughput screening, and systems biology Summaries of how these techniques and methods are used to discover new central nervous system agents, antiviral agents, respiratory drugs, oncology drugs, and more Specific approaches to drug discovery, including problems that are encountered, solutions to these problems, and limitations of various methods and techniques The thorough coverage and practical, scientifically valid problem-solving approach of Drug Discovery Handbook will serve as an invaluable aid in the complex task of developing new drugs.
Congressional Record
The Congressional Record is the official record of the proceedings and debates of the United States Congress. It is published daily when Congress is in session. The Congressional Record began publication in 1873. Debates for sessions prior to 1873 are recorded in The Debates and Proceedings in the Congress of the United States (1789-1824), the Register of Debates in Congress (1824-1837), and the Congressional Globe (1833-1873)
Molecular Biology of the Cell
MBC online publishes papers that describe and interpret results of original research conserning the molecular aspects of cell structure and function.
Functional Nanostructures for Sensors, Optoelectronic Devices and Drug Delivery
Nanoparticles and nanostructured materials represent an active area of research and impact in many application fields. The recent progress obtained in the synthesis of nanomaterials, and the fundamental understanding of their properties, has driven significant advances for their technological applications. The Special Issue “Functional Nanostructures for Sensors, Optoelectronic Devices and Drug Delivery” aims to provide an overview of the current research activities in the field of nanostructured materials with a particular emphasis on their potential applications for sensors, optoelectronic devices and biomedical systems. The Special Issue includes submission of original research articl...
