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Life Atomic
After World War II, the US Atomic Energy Commission (AEC) began mass-producing radioisotopes, sending out nearly 64,000 shipments of radioactive materials to scientists and physicians by 1955. Even as the atomic bomb became the focus of Cold War anxiety, radioisotopes represented the government’s efforts to harness the power of the atom for peace—advancing medicine, domestic energy, and foreign relations. In Life Atomic, Angela N. H. Creager tells the story of how these radioisotopes, which were simultaneously scientific tools and political icons, transformed biomedicine and ecology. Government-produced radioisotopes provided physicians with new tools for diagnosis and therapy, specifica...
The Life of a Virus
We normally think of viruses in terms of the devastating diseases they cause, from smallpox to AIDS. But in The Life of a Virus, Angela N. H. Creager introduces us to a plant virus that has taught us much of what we know about all viruses, including the lethal ones, and that also played a crucial role in the development of molecular biology. Focusing on the tobacco mosaic virus (TMV) research conducted in Nobel laureate Wendell Stanley's lab, Creager argues that TMV served as a model system for virology and molecular biology, much as the fruit fly and laboratory mouse have for genetics and cancer research. She examines how the experimental techniques and instruments Stanley and his colleagues developed for studying TMV were generalized not just to other labs working on TMV, but also to research on other diseases such as poliomyelitis and influenza and to studies of genes and cell organelles. The great success of research on TMV also helped justify increased spending on biomedical research in the postwar years (partly through the National Foundation for Infantile Paralysis's March of Dimes)—a funding priority that has continued to this day.
Science Without Laws
A comparison of the use of model systems and exemplary cases across fields in the natural and social sciences.
The Animal-human Boundary
An examination of the difficulties in fundamentally differentiating humans from all other animals.
Risk on the Table
Over the last century, the industrialization of agriculture and processing technologies have made food abundant and relatively inexpensive for much of the world’s population. Simultaneously, pesticides, nitrates, and other technological innovations intended to improve the food supply’s productivity and safety have generated new, often poorly understood risks for consumers and the environment. From the proliferation of synthetic additives to the threat posed by antibiotic-resistant bacteria, the chapters in Risk on the Table zero in on key historical cases in North America and Europe that illuminate the history of food safety, highlighting the powerful tensions that exists among scientific understandings of risk, policymakers’ decisions, and cultural notions of “pure” food.
Feminism in Twentieth-Century Science, Technology, and Medicine
What useful changes has feminism brought to science? Feminists have enjoyed success in their efforts to open many fields to women as participants. But the effects of feminism have not been restricted to altering employment and professional opportunities for women. The essays in this volume explore how feminist theory has had a direct impact on research in the biological and social sciences, in medicine, and in technology, often providing the impetus for fundamentally changing the theoretical underpinnings and practices of such research. In archaeology, evidence of women's hunting activities suggested by spears found in women's graves is no longer dismissed; computer scientists have used femi...
Culturing Life
How did cells make the journey, one we take so much for granted, from their origin in living bodies to something that can be grown and manipulated on artificial media in the laboratory, a substantial biomass living outside a human body, plant, or animal? This is the question at the heart of Hannah Landecker's book. She shows how cell culture changed the way we think about such central questions of the human condition as individuality, hybridity, and even immortality and asks what it means that we can remove cells from the spatial and temporal constraints of the body and "harness them to human intention." Rather than focus on single discrete biotechnologies and their stories--embryonic stem c...
Looking at it from Asia: the Processes that Shaped the Sources of History of Science
How do Documents Become Sources? Perspectives from Asia and Science Florence Bretelle-Establet From Documents to Sources in Historiography The present volume develops a specific type of critical analysis of the written documents that have become historians’ sources. For reasons that will be explained later, the history of science in Asia has been taken as a framework. However, the issue addressed is general in scope. It emerged from reflections on a problem that may seem common to historians: why, among the huge mass of written documents available to historians, some have been well studied while others have been dismissed or ignored? The question of historical sources and their (unequal) use in historiography is not new. Which documents have been used and favored as historical sources by historians has been a key historiographical issue that has occupied a large space in the historical production of the last four decades, in France at least.
Pavlov's Physiology Factory
Russian physiologist and Nobel Prize winner Ivan Pavlov is most famous for his development of the concept of the conditioned reflex and the classic experiment in which he trained a dog to salivate at the sound of a bell. In this study, Daniel P. Todes explores Pavlov's early work in digestive physiology through the structures and practices of his landmark laboratory - the physiology department of the Imperial Institute for Experimental Medicine.
Making Mice
Making Mice blends scientific biography, institutional history, and cultural history to show how genetically standardized mice came to play a central role in contemporary American biomedical research. Karen Rader introduces us to mouse "fanciers" who bred mice for different characteristics, to scientific entrepreneurs like geneticist C. C. Little, and to the emerging structures of modern biomedical research centered around the National Institutes of Health. Throughout Making Mice, Rader explains how the story of mouse research illuminates our understanding of key issues in the history of science such as the role of model organisms in furthering scientific thought. Ultimately, genetically standardized mice became icons of standardization in biomedicine by successfully negotiating the tension between the natural and the man-made in experimental practice. This book will become a landmark work for its understanding of the cultural and institutional origins of modern biomedical research. It will appeal not only to historians of science but also to biologists and medical researchers.
