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This book attempts to cover the most frequent problems of supportive care in detail, especially the prevention, diagnosis and treatment of infections, adverse events in the gastrointestinal tract, and the treatment of cytotoxic drug extravasation with special consideration of recently introduced cytotoxic agents. The rational use of hematopoietic growth factors for the reversal of disease- or treatment-related neutropenia, anemia and thrombocytopenia are discussed extensively. Further issues considered include anticoagulant prophylaxis, quality of life and recent advances in the use of effective antiemetics, which have increased the tolerability of standard chemotherapy and radiotherapy, and have opened up new ways of enhancing treatment. Supportive care requires an interdisciplinary approach. This book, therefore, is designed to provide an up-to-date overview for oncologists as well as general physicians, nurses, pharmacists, and all those giving care to cancer patients.
Better therapy of acute leukemias depends ultimately on better understanding of the distinction between leukemic and normal progenitor cells. This hugely important new book describes the current knowledge of acute leukemia biology and discusses new classification systems that have arisen as a result of emerging insights into pathogenesis. Estey, Faderl and Kantarjian, who all work at the respected Anderson Cancer Center in Houston, Texas, USA, examine in detail advances in the treatment of particular types of acute leukemia. Their book also covers the management of acute leukemia in general as well as the development of new therapies. This book will be extremely useful to clinicians.
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A surge of political trends and upheavals all over the world confronts German foreign policy with a world that is dramatically different from Berlin Republic unification in 1990. Brexit, American de-commitment to Europe and the rise of isolationist, populist forces within Germany as well as in other European countries and the U.S. have undermined the foundations of Germany's foreign policy. Germany is suddenly faced with another historical shift that is starting to shake the bedrock of its foreign policy. A council of experts for strategic foresight can address Germany's strategic cultural deficit, its civilian power fixation, its resorts principle of ministerial independence, and its coalition governance conflicts.
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