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Bacterial toxins that act inside cells interact very specifically with key components of the cell and some even manipulate the cell in subtle ways for their own purposes. These potent toxins, described in this 2005 book, will be of interest to both microbiologists and cell biologists. Some of these toxins are conventional multidomain toxins that are self-programmed to enter cells. Others are delivered by type III mechanisms, often as a package of potent molecules. The molecular targets for all these toxins mediate signal transduction and the cell cycle to regulate the crucial processes of cell growth, cell division and differentiation. Thus these potent toxins are not only responsible for disease, but also provide a powerful set of tools with which to interrogate the biology of the cell. In addition such toxins may act directly to promote carcinogenesis and hence their study is also of interest in a wider context.
The English Marvel is a multiskill-based series in English that adheres to the National Curriculum Framework and the advances made in ELT pedagogical principles. Having a learner-centred approach, the series develops essential communication skills and integrates the four language skills of Reading, Writing, Listening and Speaking.
THE FASTEST 30 BALLGAMES is a World Record journey of dedicated Ballpark Chaser, Chuck Booth. In the summer of 2009, Booth accomplished this amazing feat of attending a full baseball game at every Major League Baseball home teams ballpark in only 24 calendar days. Booth managed this after falling just short of the record in 2008. The book chronicles the story of Booth as he rearranged his life to attempt the World Record after hearing the inspirational story of Jim Maclaren who faced two near death experiences--and how Jim overcame being a quadriplegic to become one of the most respected motivational speakers in America. The story features write-ups of all ballparks Booth visited during the ...
Diversity, Equity, and Inclusion (DEI) are foundational principles in fostering a just and equitable society. Embracing diversity involves recognizing and valuing the unique attributes and experiences of individuals from different backgrounds. Equity ensures that everyone has fair access to opportunities and resources, tailored to meet their specific needs. Inclusion goes beyond representation, fostering an environment where all individuals feel respected, valued, and able to contribute fully. In educational settings, DEI initiatives are crucial in addressing disparities, promoting understanding, and preparing students for a diverse world. By prioritizing DEI, we build communities that celebrate differences and work towards collective progress.
Bioremediation technologies for environments contaminated by organic and inorganic pollutants are a major focus of researchers and scientists worldwide. The chemical control of agricultural pests and advocacy for sustainable agriculture have led to the development of new paradigms in environmental remediation. This book covers recent advances in the bioremediation technology of organic and inorganic pollutants in the environment.
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Found in two-thirds of the world, rabies is a devastating infectious disease with a 99.9 percent case-fatality rate and no cure once clinical signs appear. Rabies in the Streets tells the compelling story of the relationship between people, street animals, and rabies in India, where one-third of human rabies deaths occur. Deborah Nadal argues that only a One Health approach of “interspecies camaraderie” can save people and animals from the horrors of rabies and almost certain death. Grounded in multispecies ethnography, this book leads the reader through the streets and slums of Delhi and Jaipur, where people and animals, such as dogs, cows, and macaques, interact intimately and sometime...
Describes the barriers to progress and highlights the positive impact of the CDAGM in relation to institutions such as the BBC, ITV, Newsquest, Westminster Media Forum, DCMS and Parliamentary Select Committees. This book is suitable for those concerned with democracy, fairness and social inclusion.
This textbook provides a comprehensive and state-of-the-art overview of the major issues specific to the field of pediatric gastroenterology, hepatology, and nutrition. The first part of the book, Gastroenterology and Nutrition, presents in a systematic way the overall scope of issues encountered by children (newborn to teenagers) suffering from disorders of the gastrointestinal tract, pancreas and/or presenting nutritional issues. These chapters are structured in logical sections to facilitate consultation and include major topics ranging from congenital disorders to gastrointestinal problems of the newborn, infectious diseases of the gastrointestinal tract, and approach to nutritional prob...
This book looks at India of the 1950s and 1960s while it was still emerging from two centuries of colonial rule and striving to come together as a nation. It critically explores the history of nationalism and identity in Northeastern India, a region with diverse ethnolinguistic communities and people, through the personal history of the first Manipuri (Meitei) direct recruit in the Indian Administrative Services. The book weaves in autobiographical stories with the story of Northeast India, capturing its politics, socio-cultural distinctiveness and milieus that set the region apart from the rest of the country. It covers the career of the author in the IAS, serving in Manipur and Karnataka, ...