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MHC Protocols
The aim of MHC Protocols is to document protocols that can be used for the analysis of genetic variation within the human major histocompatibility complex (MHC; HLA region). The human MHC encompasses approximately 4 million base pairs on the short arm of chromosome 6 at cytogenetic location 6p21. 3. The region is divided into three subregions. The telomeric class I region contains the genes that encode the HLA class I molecules HLA-A, -B, and -C. The centromeric class II region contains the genes encoding the HLA class II molecules HLA-DR, -DQ, and -DP. In between is the class III region, originally identified because it contains genes encoding components of the complement pathway. The entir...
The HLA Complex in Biology and Medicine
A comprehensive guide to the HLA (Human Leukocyte Antigen) system for immunologists and clinicians, this book contains up-to-date information on the MHC (Major Histocompatibility Complex) and its role in the immune response and in various diseases. The book explores the biological significance and role of the HLA system in organ and haematopoietic stem cell transplantation management. This volume is an invaluable guide to the full spectrum of HLA-related science while also serving as a conceptual and technical resource for those involved in HLA-related research and in clinical or surgical practice. In addition, it will be a primary point of contact for individuals working in other areas who suddenly find that their research is drawing them into the complexities of HLA genetics.
The Trouble with Medical Journals
It is a turbulent time for STM publishing. With moves towards open access to scientific literature, the future of medical journals is uncertain and unpredictable. This is the only book of its kind to address this problematic issue. Richard Smith, a previous editor of the British Medical Journal for twenty five years and one of the most influential people within medical journals and medicine depicts a compelling picture of medical publishing. Drawn from the author's own extensive and unrivalled experience in medical publishing, Smith provides a refreshingly honest analysis of current and future trends in journal publishing including peer review, ethics in medical publishing, the influence of ...
Prehistoric Iberia
The symposium "Prehistoric Iberia: genetics, anthropology and linguistics" was held in the Circulo de Bellas Artes, Madrid on 16th -17th November 1998. The idea was bringing together specialists who could address not clearly resolved historic and prehistoric issues regarding ancient Iberian and Mediterranean populations, following a multidisciplinary approach. This was necessary in the light of the new bulk of genetic, archeological and linguistic data obtained with the new DNA technology and the recent discoverings in the other fields. Genes may now be easily studied in populations, particularly HLA genes and markers of the mitochondrial DNA and the Y chromosome. Basques, Iberians, North Af...
The Persistence of the Palestinian Question
In this erudite and groundbreaking series of essays, renowned author Joseph Massad takes a radical departure from mainstream analysis in order to expose the causes for the persistence of the Palestinian Question.
Traces of History
Traces of History presents a new approach to race and to comparative colonial studies. Bringing a historical perspective to bear on the regimes of race that colonizers have sought to impose on Aboriginal people in Australia, on Blacks and Native Americans in the United States, on Ashkenazi Jews in Western Europe, on Arab Jews in Israel/Palestine, and on people of African descent in Brazil, this book shows how race marks and reproduces the different relationships of inequality into which Europeans have coopted subaltern populations: territorial dispossession, enslavement, confinement, assimilation, and removal. Charting the different modes of domination that engender specific regimes of race and the strategies of anti-colonial resistance they entail, the book powerfully argues for cross-racial solidarities that respect these historical differences.
The Invention of the Jewish People
The bestselling analysis of Jewish history, by a leading Israeli historian.
Major Histocompatibility Complex
Every biological system is the outcome of evolution and has a history all its own. This history dictates how the system works and why it has certain properties and not others. This is why we need to study not only the structure and function, but also the history of the system. This argument undoubtedly applies to the study of the immune system and also to the study of the major histocompatibility complex (MHC). Since 1989, researchers of various scientific disciplines who share a deep inter est in MHC evolution have held a meeting every two years to discuss their latest research developments, exchange ideas, and foster friendship. Together with my colleagues Drs. Naoyuki Takahata and Yoko Sa...
Clinical Transplants
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In Search of Human Evolution
In Search of Human Evolution focuses on sources of funding and fieldwork in Mexico, Siberia, Hungary, and the Aleutian Islands. It reviews how the evolutionary questions were generated, grant proposals submitted to specific agencies, and permissions obtained from each country and community. This book also includes information on how the field research was organized, data collected, and graduate students and post docs trained. The results of each of these investigations were statistically analysed and summarized.
