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IVF in the Medically Complicated Patient
Each patient seeking assisted reproduction has a unique set of circumstances that affects the outcome of treatment. Particularly challenging are those patients with pre-existing medical conditions or those receiving medical therapies that may impact the safety and success of their IVF treatments. Prior identification and preparation of the patient
Biofortification for Nutrient-Rich Crops
Biofortification is a widely accepted cost-effective agricultural strategy to improve the nutrient deficiency in populations. It is especially useful in low income and developing nations. Strategies for biofortification employ crop breeding, targeted genetic alteration, and agronomy, show promise for addressing multiple forms of human malnutrition. To increase the bioavailability of food nutrients, biofortification efforts must focus on improving the nutrient content of food and decreasing anti-nutrients. This book covers the basics of biofortification, international efforts, challenges, opportunities, and the use of the latest omics technologies in addition to classical approaches. It cover...
Omics and System Biology Approaches for Delivering Better Cereals
Cereals like wheat, rice, maize, and barley have long been the dominant crops in agriculture, providing a significant portion of our food supply. Plant breeders and geneticists have always been interested in improving the yield and quality of cereals. The primary challenges in cereal breeding lie in adapting to climate change and enhancing yield and stress tolerance. In recent years, omics approaches such as genomics, transcriptomics, proteomics, and metabolomics have emerged as valuable tools to understand the genetic and molecular basis of cereal development under optimum and stress conditions. However, studying individual datasets for different cereals has limited our comprehensive unders...
Emerging Trends and Advances in the Socioeconomic Applications of Beneficial Microbes
Please note that Systems Microbiology does not consider descriptive studies that are solely based on amplicon (e.g., 16S rRNA) profiles, unless they are accompanied by a clear hypothesis and experimentation, and provide insight into the microbiological system or process being studied. Microorganisms comprise an integral component of our ecosystem and are closely associated with human lives. Found in diverse niches, microbes can adapt and thrive in challenging climatic fluctuations and environments. A recent panel of the United Nations General Assembly (UNGA) Science Summit contemplated: “understanding the world of microbes is imperative either to curb dangerous effects or to harness their ...
Thymus Therapy: The Past, Present and Future
This dense study conducted by Prof. Dr. Mike K.S. Chan and Prof. Dr. Michelle B.F. Wong, with the support of a professional team of researchers, highlights how important is to delve deeper into the study of the thymus gland which plays a crucial role in immune system health. As we read in the forewords the topics presented are the results of a collaboration between experts coming from various fields such as immunology, gerontology, regenerative medicine, and clinical practice. This comprehensive book can strengthen the communication and collaboration among these disciplines, fostering a more holistic approach to addressing age-related health challenges. Bioregenerative medicine in general, a...
The Pomegranate Genome
The volume is a comprehensive resource for researchers, scholars, and enthusiasts in the field of pomegranate research. It delves into various aspects of the pomegranate crop, providing an extensive coverage of its botany, taxonomy, germplasm conservation and utilization, genome, and functional genomics. The work provides a detailed understanding of the pomegranate's genetic makeup and its potential applications. The research presented in the book focuses on the identification and analysis of key genes and gene families of pomegranates, and sheds light on their functions and contributions to the plant's growth and development. By uncovering these genetic insights, researchers can further exp...
Protein-based Therapeutics
This book provides an overview of the essential characteristics and clinical applications of therapeutic proteins against human diseases, including cancers, immune disorders, infections, and other diseases. It presents the latest advancements in protein engineering techniques for producing desirable therapeutic proteins. The book also covers the strategies used to formulate and deliver systemic therapeutic proteins, approved protein therapeutics and their targets, and pharmacogenetic biomarkers. Further, it discusses challenges associated with the clinical implications of therapeutic proteins, including safety, immunogenicity, protein stability, degradation, and efficacy. It illustrates the development of biosimilar antibodies, optimization strategies for producing biobetter antibodies, and presents fundamental concepts about biosuperior therapeutics. Lastly, it includes a discussion about protein-based vaccines against bacterial and viral infections.
The Unsung Verses
THE UNSUNG VERSES: A Poetry Collection is not just a book, it is a dream come true. Getting a book published by including poems which are extremely close to my heart, was always a desire, which blossomed in my heart over the years of my growing up. Literature is the food for soul for me. I have always took pride in collecting books from writers across the globe. I am a voracious reader and a creative writer. I write poems, stories and articles in English and Hindi. This Anthology has 51 poems composed by me. I derive inspiration from daily life and various aspects from the myriad human emotions. Life is not life, if emotions are drained from the fountain of the heart. Majority of my poems ar...
Topology and Quantum Theory in Interaction
This volume contains the proceedings of the NSF-CBMS Regional Conference on Topological and Geometric Methods in QFT, held from July 31–August 4, 2017, at Montana State University in Bozeman, Montana. In recent decades, there has been a movement to axiomatize quantum field theory into a mathematical structure. In a different direction, one can ask to test these axiom systems against physics. Can they be used to rederive known facts about quantum theories or, better yet, be the framework in which to solve open problems? Recently, Freed and Hopkins have provided a solution to a classification problem in condensed matter theory, which is ultimately based on the field theory axioms of Graeme S...
Computer-Aided Drug Design
This book provides up-to-date information on bioinformatics tools for the discovery and development of new drug molecules. It discusses a range of computational applications, including three-dimensional modeling of protein structures, protein-ligand docking, and molecular dynamics simulation of protein-ligand complexes for identifying desirable drug candidates. It also explores computational approaches for identifying potential drug targets and for pharmacophore modeling. Moreover, it presents structure- and ligand-based drug design tools to optimize known drugs and guide the design of new molecules. The book also describes methods for identifying small-molecule binding pockets in proteins, and summarizes the databases used to explore the essential properties of drugs, drug-like small molecules and their targets. In addition, the book highlights various tools to predict the absorption, distribution, metabolism, excretion (ADME) and toxicity (T) of potential drug candidates. Lastly, it reviews in silico tools that can facilitate vaccine design and discusses their limitations.
