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Development and Validation of a Multi-institutional Nomogram of Outcomes for PSMA-PET-based Salvage Radiotherapy for Recurrent Prostate Cancer
Abstract: Importance Prostate-specific antigen membrane positron-emission tomography (PSMA-PET) is increasingly used to guide salvage radiotherapy (sRT) after radical prostatectomy for patients with recurrent or persistent prostate cancer. Objective To develop and validate a nomogram for prediction of freedom from biochemical failure (FFBF) after PSMA-PET-based sRT. Design, Setting, and Participants This retrospective cohort study included 1029 patients with prostate cancer treated between July 1, 2013, and June 30, 2020, at 11 centers from 5 countries. The initial database consisted of 1221 patients. All patients had a PSMA-PET scan prior to sRT. Data were analyzed in November 2022. Exposur...
MEDINFO 2017: Precision Healthcare Through Informatics
Medical informatics is a field which continues to evolve with developments and improvements in foundational methods, applications, and technology, constantly offering opportunities for supporting the customization of healthcare to individual patients. This book presents the proceedings of the 16th World Congress of Medical and Health Informatics (MedInfo2017), held in Hangzhou, China, in August 2017, which also marked the 50th anniversary of the International Medical Informatics Association (IMIA). The central theme of MedInfo2017 was "Precision Healthcare through Informatics", and the scientific program was divided into five tracks: connected and digital health; human data science; human, o...
The Oxford Handbook of Computational Linguistics
Ruslan Mitkov's highly successful Oxford Handbook of Computational Linguistics has been substantially revised and expanded in this second edition. Alongside updated accounts of the topics covered in the first edition, it includes 17 new chapters on subjects such as semantic role-labelling, text-to-speech synthesis, translation technology, opinion mining and sentiment analysis, and the application of Natural Language Processing in educational and biomedical contexts, among many others. The volume is divided into four parts that examine, respectively: the linguistic fundamentals of computational linguistics; the methods and resources used, such as statistical modelling, machine learning, and corpus annotation; key language processing tasks including text segmentation, anaphora resolution, and speech recognition; and the major applications of Natural Language Processing, from machine translation to author profiling. The book will be an essential reference for researchers and students in computational linguistics and Natural Language Processing, as well as those working in related industries.
My Favorite Burgundies
"My Favorite Burgundies is a more personal follow-up to--but not a comprehensive revision of--Coates' The Wines of Burgundy (California, 2008). The book is based on the author's many subsequent tastings and travels through the region since the publication of his last book five years ago. Chapter 1 includes descriptions of Burgundy's most renowned vineyards, including their particular history, geography, and soil conditions, as well as tasting notes of various producer's single-bottle offerings from these sites. Chapter 2 describes the region's most distinguished domaines, with Coates impressions of the proprietors, facilities, and wine-making philosophies, along with vertical tasting notes (...
Mes TD de contrôle de gestion
Des travaux dirigés pour comprendre et approfondir son cours de Contrôle de gestion : Une méthodologie détaillée pour chaque type d'exercices ;Des exercices d'application, corrigés et détaillés ;Les notions essentielles du cours. Cet ouvrage pourra accompagner les étudiants tout au long de leurs révisions en vue des examens ou des concours.
The Wines of Burgundy
Ten years after the publication of the highly acclaimed, award-winning Côte D'Or: A Celebration of the Great Wines of Burgundy, the "Bible of Burgundy," Clive Coates now offers this thoroughly revised and updated sequel. This long-awaited work details all the major vintages from 2006 back to 1959 and includes thousands of recent tasting notes of the top wines. All-new chapters on Chablis and Côte Chalonnaise replace the previous volume's domaine profiles. Coates, a Master of Wine who has spent much of the last thirty years in Burgundy, considers it to be the most exciting, complex, and intractable wine region in the world, and the one most likely to yield fine wines of elegance and finesse. This book is an indispensable guide for amateur and professional alike by one of the world's leading wine experts, writing with his habitual expertise, lucidity, and unequaled firsthand knowledge.
Cytogenomics
Cytogenomics demonstrates that chromosomes are crucial in understanding the human genome and that new high-throughput approaches are central to advancing cytogenetics in the 21st century. After an introduction to (molecular) cytogenetics, being the basic of all cytogenomic research, this book highlights the strengths and newfound advantages of cytogenomic research methods and technologies, enabling researchers to jump-start their own projects and more effectively gather and interpret chromosomal data. Methods discussed include banding and molecular cytogenetics, molecular combing, molecular karyotyping, next-generation sequencing, epigenetic study approaches, optical mapping/karyomapping, an...
