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ROLE OF THE MODULATING FACTORS ON THE PHENOTYPE OF SICKLE CELL DISEASE
Sickle cell first reported by James B Herrick; (Herrick 1910) a Chicago cardiologist and professor of medicine United States, in red blood cells. The disease was named "sickle-cell anaemia" by Verne Mason in 1922, then a medical resident at Johns Hopkins Hospital.(Konotey-Ahulu 2004) However, some elements of the disease had been recognized earlier: A paper in the Southern Journal of Medical Pharmacology in 1846 described the absence of a spleen in the autopsy of a runaway slave.
Nuclear Medicine
The book is a compilation of guidelines from various organizations such as Society of Nuclear Medicine & Molecular Imaging, European Association of Nuclear Medicine, American College of Radiology and International Atomic Energy Agency. The description of the procedures is simple, easy to understand and current. The aim of this book is: a) Nuclear medicine professionals can use this book as a quick reference about how a procedure is to be performed. The set of instructions given to patient before, during and after the procedure have also been included in each chapter. b) To educate general physicians about nuclear medicine procedures. The procedures are explained briefly with common indications and precautions. Normal and abnormal nuclear medicine images have also been included for quick comparison. c) To educate paramedical staff or healthcare professionals so that they send patients to nuclear medicine department after proper preparation. d) To educate patients who come for nuclear medicine procedure. e) To clarify apprehensions and doubts which arise in the mind of the patients.
Vascular Responses to Pathogens
Vascular Responses to Pathogens focuses on the growing research from leaders in the field for both the short and long-term impact of pathogens on the vasculature. It discusses various organisms, including bacteria, parasites, and viruses, and their role in key events leading to vascular disease. Formatted to discuss the topic of the interaction of pathogens with the vascular rather than individual diseases described separately, this reference demonstrates that common mechanisms are at play in many different diseases because they have a similar context, their vasculature. This all-inclusive reference book is a must-have tool for researchers and practicing clinicians in the areas of vascular b...
Disorders of Hemoglobin
Completely revised new edition of the definitive reference on disorders of hemoglobin.
Spain, a Global History
From the late fifteenth to the nineteenth centuries, the Hispanic Monarchy was one of the largest and most diverse political communities known in history. At its apogee, it stretched from the Castilian plateau to the high peaks of the Andes; from the cosmopolitan cities of Seville, Naples, or Mexico City to Santa Fe and San Francisco; from Brussels to Buenos Aires and from Milan to Manila. During those centuries, Spain left its imprint across vast continents and distant oceans contributing in no minor way to the emergence of our globalised era. This was true not only in an economic sense-the Hispano-American silver peso transported across the Atlantic and the Pacific by the Spanish fleets wa...
Randomization, Masking, and Allocation Concealment
Randomization, Masking, and Allocation Concealment is indispensable for any trial researcher who wants to use state of the art randomization methods, and also wants to be able to describe these methods correctly. Far too often the subtle nuances that distinguish proper randomization from flawed randomization are completely ignored in trial reports that state only that randomization was used, with no additional information. Experience has shown that in many cases, the type of randomization that was used was flawed. It is only a matter of time before medical journals and regulatory agencies come to realize that we can no longer rely on (or publish) flawed trials, and that flawed randomization ...
Disease Control Priorities in Developing Countries
Based on careful analysis of burden of disease and the costs ofinterventions, this second edition of 'Disease Control Priorities in Developing Countries, 2nd edition' highlights achievable priorities; measures progresstoward providing efficient, equitable care; promotes cost-effectiveinterventions to targeted populations; and encourages integrated effortsto optimize health. Nearly 500 experts - scientists, epidemiologists, health economists,academicians, and public health practitioners - from around the worldcontributed to the data sources and methodologies, and identifiedchallenges and priorities, resulting in this integrated, comprehensivereference volume on the state of health in developing countries.
Spanish Books in the Europe of the Enlightenment (Paris and London)
In Spanish Books in the Europe of the Enlightenment (Paris and London) Nicolás Bas examines the image of Spain in eighteenth-century Europe, and in Paris and London in particular. His material has been scoured from an exhaustive interrogation of the records of the book trade. He refers to booksellers’ catalogues, private collections, auctions, and other sources of information in order to reconstruct the country’s cultural image. Rarely have these sources been searched for Spanish books, and never have they been as exhaustively exploited as they are in Bas’ book. Both England and France were conversant with some very negative ideas about Spain. The Black Legend, dating back to the sixteenth century, condemned Spain as repressive and priest-ridden. Bas shows however, that an alternative, more sympathetic, vision ran parallel with these negative views. His bibliographical approach brings to light the Spanish books that were bought, sold and ultimately read. The impression thus obtained is likely to help us understand not only Spain’s past, but also something of its present.
