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Measurement, Modeling and Automation in Advanced Food Processing
This book review series presents current trends in modern biotechnology. The aim is to cover all aspects of this interdisciplinary technology where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science. Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification. In general, special volumes are edited by well-known guest editors. The series editor and publisher will however always be pleased to receive suggestions and supplementary information. Manuscripts are accepted in English.
Measurement, Monitoring, Modelling and Control of Bioprocesses
Automated Measurement and Monitoring of Bioprocesses: Key Elements of the M3C Strategy, by Bernhard Sonnleitner Automatic Control of Bioprocesses, by Marc Stanke, Bernd Hitzmann An Advanced Monitoring Platform for Rational Design of Recombinant Processes, by G. Striedner, K. Bayer Modelling Approaches for Bio-Manufacturing Operations, by Sunil Chhatre Extreme Scale-Down Approaches for Rapid Chromatography Column Design and Scale-Up During Bioprocess Development, by Sunil Chhatre Applying Mechanistic Models in Bioprocess Development, by Rita Lencastre Fernandes, Vijaya Krishna Bodla, Magnus Carlquist, Anna-Lena Heins, Anna Eliasson Lantz, Gürkan Sin and Krist V. Gernaey Multivariate Data Ana...
Disposable Bioreactors
Over the past five years, the immense financial pressure on the development and manufacturing of biopharmaceuticals has resulted in the increasing use and acce- ance of disposables, which are discarded after harvest and therefore intended only for single use. In fact, such disposables are implemented in all the main bioprocess production stages today and an even higher growth than those in the biopharmac- tical market is predicted (reaching double figures). Alongside disposable filter capsules, membrane chromatography units, tubing, connectors, flexible containers processing or containing fluids, freezer systems, mixers and pumps, and fully c- trolled disposable bioreactors of up to 2,000 L ...
Raman Spectroscopy in the Food Industry
Raman spectroscopy has become one of the most important techniques effectively applied to detect specific analytes and microorganisms in food samples. Raman Spectroscopy in the Food Industry provides a comprehensive overview of the current state of the art and future prospects of Raman spectroscopy in food analyses. Through in-depth chapters, the authors discuss the fundamental principles of Raman spectroscopy, its instrumentation, methodologies, and its diverse applications across various food matrices. Real-world case studies and practical examples underscore the transformative potential of Raman spectroscopy in reshaping our understanding, analysis, and innovation within the realm of food...
Upstream Industrial Biotechnology, 2 Volume Set
Biotechnology represents a major area of research focus, and many universities are developing academic programs in the field. This guide to biomanufacturing contains carefully selected articles from Wiley's Encyclopedia of Industrial Biotechnology, Bioprocess, Bioseparation, and Cell Technology as well as new articles (80 in all,) and features the same breadth and quality of coverage and clarity of presentation found in the original. For instructors, advanced students, and those involved in regulatory compliance, this two-volume desk reference offers an accessible and comprehensive resource.
Hybrid Nature
A history of of the industrial ecosystem that focuses on the biological sewage treatment plant as an early example. Biological sewage treatment, like electricity, power generation, telephones, and mass transit, has been a key technology and a major part of the urban infrastructure since the late nineteenth century. But sewage treatment plants are not only a ubiquitous component of the modern city, they are also ecosystems -- a hybrid variety that incorporates elements of both nature and industry and embodies multiple contradictions. In Hybrid Nature, Daniel Schneider offers an environmental history of the biological sewage treatment plant in the United States and England, viewing it as an ea...
Optical Sensor Systems in Biotechnology
Of all things natural, light is the most sublime. From the very existential belief of the origins of the universe to its role in the evolution of life on earth, light has been inextricably woven into every aspect of our lives. I am grateful to Springer-Verlag and Thomas Scheper for this invitation to organize this volume that continues to expand the use of light to create next generation sensing applications. Indeed, the very act of expanding the frontiers of learning and knowledge are referred to in many languages and cultures as enlightenment. Early optical instruments relied largely on simple combinations of mirrors, prisms and lenses. With these simple devices, substantial progress was m...
Encyclopedia of Microbiology, Four-Volume Set
The First Edition of the Encyclopedia of Microbiology was hailed by leading scientists and researchers around the world as "excellent," "outstanding," and "impressive." This Second Edition will serve as an up-to-date version of this reference which has been useful to academic, industrial, and personal libraries for years. The Encyclopedia of Microbiology, Second Edition both challenges and stimulates the reader, and illustrates the importance of microbiology, a field that cannot be over emphasized in this booming biotechnology age. Key Features * Completely redesigned and revised approach with 65% new material * Contains approximately 300 articles, 1000 illustrations, and 400 tables * New design includes thematic table of contents, combined glossary of terms, and appendix * Provides color plate sections in each volume * 17 subject areas, including exciting coverage of microbes in extreme environments and microbes in emerging infections
Genomics and Systems Biology of Mammalian Cell Culture
Transcriptome Analysis, by Frank Stahl, Bernd Hitzmann, Kai Mutz, Daniel Landgrebe, Miriam Lübbecke, Cornelia Kasper, Johanna Walter und Thomas Scheper Transcriptome Data Analysis for Cell Culture Processes, by Marlene Castro-Melchor, Huong Le und Wei-Shou Hu Modeling Metabolic Networks for Mammalian Cell Systems: General Considerations, Modeling Strategies, and Available Tools, by Ziomara P. Gerdtzen Metabolic Flux Analysis in Systems Biology of Mammalian Cells, by Jens Niklas und Elmar Heinzle Advancing Biopharmaceutical Process Development by System-Level Data Analysis and Integration of Omics Data, by Jochen Schaub, Christoph Clemens, Hitto Kaufmann und Torsten W. Schulz Protein Glycosylation and Its Impact on Biotechnology, by Markus Berger, Matthias Kaup und Véronique Blanchard Protein Glycosylation Control in Mammalian Cell Culture: Past Precedents and Contemporary Prospects, by Patrick Hossler Modeling of Intracellular Transport and Compartmentation, by Uwe Jandt und An-Ping Zeng Genetic Aspects of Cell Line Development from a Synthetic Biology Perspective, by L. Botezatu, S. Sievers, L. Gama-Norton, R. Schucht, H. Hauser und D. Wirth.
Digital Twins
This is the second of two volumes that together provide an overview of the latest advances in the generation and application of digital twins in bioprocess design and optimization. Both processes have undergone significant changes over the past few decades, moving from data-driven approaches into the 21st-century digitalization of the bioprocess industry. Moreover, the high demand for biotechnological products calls for efficient methods during research and development, as well as during tech transfer and routine manufacturing. In this regard, one promising tool is the use of digital twins, which offer a virtual representation of the bioprocess. They reflect the mechanistics of the biologica...
