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Théo Stavropoulos
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Stem Cell and Biologic Scaffold Engineering
Tissue engineering and regenerative medicine is a rapidly evolving research field which effectively combines stem cells and biologic scaffolds in order to replace damaged tissues. Biologic scaffolds can be produced through the removal of resident cellular populations using several tissue engineering approaches, such as the decellularization method. Indeed, the decellularization method aims to develop a cell-free biologic scaffold while keeping the extracellular matrix (ECM) intact. Furthermore, biologic scaffolds have been investigated for their in vitro potential for whole organ development. Currently, clinical products composed of decellularized matrices, such as pericardium, urinary bladd...
Immunology and Infectious Disease
This unique volume provides a mechanistic look at key aspects of the inflammatory response seen in critical illness. Key cells and mediators involved in the innate inflammatory response and the pathways employed to combat infection or respond to injury are emphasized. It has become clear that a delicate balance exists to allow eradication of infection with minimal immune-mediated tissue injury in the process. For this reason an up-to-date discussion of how the inflammatory response down regulates itself has been included. The inflammatory response in the critically ill is vastly different than in healthy hosts. For this reason, discussions about the mechanisms of pharmacologic immune suppres...
The Myriad Christ
"Papers gathered here are the fruit of an international congress held at the Faculty of Theology of the Katholieke Universiteit Leuven, 18-21 November, 1997."--Pref.
Essays on International Law and Practice
This volume collects papers written by Shabtai Rosenne in the course of his distinguished career on various topics, primarily in the areas in which he is best known for his expertise: international litigation and courts, the law of treaties, the law of the sea and state responsibility. His writing on fact-finding before the International Court of Justice, treaty succession, codification and the framework agreement as the basis for the jurisdiction of the ICJ in particular remain as interesting, timely and essential today as when they were first written. The collection is accompanied by a table of cases, a table of treaties and an index for easy reference.
Finding Solid Ground: Overcoming Obstacles in Trauma Treatment
"In this chapter, we provide a brief overview of the relationships between trauma-related disorders and dissociation, describe the prevalence and presentations of dissociation among trauma survivors, and discuss the challenges that contribute to trauma-related disorders (TRD) and dissociative disorders (DDs) being "hidden in plain sight". Please note that throughout this book we use the term "trauma-related disorders" (TRD) as an overarching term that includes those who have a diagnosable trauma-related DD, which means that dissociation is typically severe, frequent, and disabling. Thus, our use of TRD in this book includes individuals with posttraumatic stress disorder (PTSD), acute stress disorder, the dissociative subtype of PTSD (DPTSD), and persons with trauma-related DDs. Since many authors consider borderline personality disorder a TRD due to the frequent occurrence of trauma, childhood maltreatment, and attachment problems in this population, we include those with trauma histories in our use of TRD as well"--
Tachykinins
The tachykinins represent one of the most thoroughly investigated family of neuropeptides, whose members and receptors have been characterized at the genetic and molecular level and whose pharmacology has now been advanced to the first clinical application. These exciting accomplishments and prospects are reviewed and discussed in this volume in an authoritative manner. Particular emphasis is laid on the development of selective non-peptide antagonists for all 3 tachykinin receptors and their potential as novel drugs in a variety of diseases. The approval of the first tachykinin receptor antagonist as an antiemetic drug is particularly highlighted, and the utility of tachykinin receptor antagonists in affective disorders, chronic obstructive airway disease and irritable bowel syndrome, to name a few indications, is extensively considered.
Novel Industry 4.0 Technologies and Applications
The Industry 4.0 paradigm has led to the creation of new opportunities for taking advantage of a set of diverse technologies in the manufacturing domain. This book touches on a series of advanced technologies and research fields, including Internet of Things, Augmented and Virtual Reality, Machine Learning, Advanced Robotics, Additive Manufacturing, System and Process Simulation, Computer-Aided Design/Engineering/Manufacturing/Process Planning Systems as well as Product Lifecycle Management Platforms. The topics covered span a series of diverse areas related to a) product design and development, b) manufacturing systems and operations, c) process engineering, and d) Industry 4.0 technologies review and realization.
