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Calcium Signaling
Calcium signaling contains a unique selection of chapters that cover a wide range of contemporary topics in this ubiquitous and diverse system of cell signaling. This book has the flavor of a primary text book, but it is much more than that. It covers topics ranging from the fundamental aspects of calcium signaling to its clinical implications, in a thoughtful and comprehensive way. It discusses cutting edge researches, and critical issues at depth, and it presents many testable hypotheses for future research. It includes the theoretical and the methodological topics as well as topics related to mathematical modeling, and simulations. If you want to read about calcium signaling in different mammalian cells, oocytes, Zebrafishes, and even in plants, in one and the same book, then this book will not disappoint you. From the beginners to the experts in the field of calcium signaling, everybody will find something useful in this very timely book.
Invertebrate Learning and Memory
The nervous system of Aplysia californica has three isoforms of protein kinase C (PKC): the conventional PKC Apl I, the novel PKC Apl II, and the atypical PKC Apl III. Each isoform has distinct requirements for activation and distinct downstream roles in synaptic plasticity. PKCs can be cleaved by calpains into constitutively active forms, called protein kinase Ms (PKMs). Multiple forms of plasticity in Aplysia are mediated by PKMs, and these may be due to cleavage of distinct isoforms of PKC. PKCs also interact in complex ways with other second messenger pathways. The diversity of PKC isoforms allows for this family of kinases to play important roles in decoding extracellular stimuli into the formation of distinct molecular memory traces.
Forget Me Not: The Neuroethical Case Against Memory Manipulation
The first philosophical monograph on the ethics of memory manipulation (MM), "Forget Me Not: The Neuroethical Case Against Memory Manipulation" contends that any attempt to directly and intentionally erase episodic memories poses a grave threat to the human condition that cannot be justified within a normative moral calculus. Grounding its thesis in four evidential effects – namely, (i) MM disintegrates autobiographical memory, (ii) the disintegration of autobiographical memory degenerates emotional rationality, (iii) the degeneration of emotional rationality decays narrative identity, and (iv) the decay of narrative identity disables one to seek, identify, and act on the good – DePergola argues that MM cannot be justified as a morally licit practice insofar as it disables one to seek, identify, and act on the good. A landmark achievement in the field of neuroethics, this book is a welcome addition to both the scholarly and professional community in philosophical and clinical bioethics.
Visiting Immigration Detention
This study of immigration detention policy in Australia presents first-hand accounts of more than 70 people visiting and supporting asylum seekers. Documenting and theorising their experiences and treatment, it delivers new perspectives on the profound human costs of hardline immigration policy, both in Australia and beyond.
Reading Nuruddin Farah
A close analysis of Farah's novels is used to track the contradictions implicit in the notion of the modern, disengaged self and how transformations of the novel in literary history attempt to negotiate this founding contradiction.
Wilson, Oklahoma
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Introduction to Early Childhood Education and Care
Ensure children of all backgrounds can thrive with an intercultural approach to early childhood education In a multicultural society such as Canada’s, early childhood educators work with children and families from a diverse mix of ethnicities, religions, languages, abilities, and lifestyles. Diversity enriches the experience of children and educators alike in these environments, but it can also present challenges in supporting each child’s growth and learning. In Introduction to Early Childhood Learning and Care, early learning specialists Carole Massing and Mary Lynne Matheson present an intercultural perspective as a foundation of equitable outcomes in early childhood education, but ju...
Wax Tablets of the Mind
Jocelyn Small's erudite volume represents a timely insight into the topical areas of literacy and memory, and provides a controversial and challenging analysis of the cognitive processes and their modes of display and retrieval.
