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Tooth Enamel Research: Enamel 10 and beyond
The Research Topic will host an overview of the most recent knowledge on enamel issued from a group of international experts who gathered at the 10th International Symposium on Dental Enamel (Enamel X). The Topic will include manuscripts describing original data, short communication, and reviews. In addition, the Topic will host abstracts and panel discussions presented at the Enamel X meeting, to highlight changing paradigms, unsolved and challenging questions, as well as translational challenges. Bringing together physics, chemistry, biochemistry and development and differentiation, contributions to this Topic will focus on the unique architecture of enamel, from nano- to macro- scale, and...
Tooth Enamel: Frontiers in Mineral Chemistry and Biochemistry, Integrative Cell Biology and Genetics
"Tooth Enamel: Frontiers in Mineral Chemistry and Biochemistry, Integrative Cell Biology and Genetics" incorporates the proceedings of the 9th International Enamel Symposium (Enamel 9) hosted in the UK and chaired by Professor Jennifer Kirkham and Professor Ariane Berdal. The topic covers cellular and molecular aspects of the development, pathology, evolution and repair or regeneration of dental enamel. The original research papers and reviews will be of interest to all enamel and biomineralization researchers. Clinicians will find up-to-date thinking and opinion on the aetiology of enamel pathologies and their potential future treatment via novel strategies for preventing, repairing and regenerating enamel.
Signaling Pathways in Developing and Pathological Tissues and Organs of the Craniofacial Complex
Head formation requires the well-orchestrated and harmonised development of various tissues and organs within the craniofacial complex. A big variety of signaling pathways are involved in this process by controlling cell proliferation, migration, differentiation, tissue morphogenesis, homeostasis and regeneration. Deregulation and malfunction of these signaling molecules may lead to mild or severe craniofacial pathologies. This eBook is a collection of articles dealing with a variety of important signals involved in the control of developmental and pathological events of craniofacial organs and tissues. These recent advances show the importance of signaling pathways in craniofacial physiology and pathology and generate important new knowledge aiming the development of new pharmaceutical products that mimic and/or block the actions of specific molecules.
Dental and Periodontal Tissues Formation and Regeneration: Current Approaches and Future Challenges
Sequential and reciprocal interactions between oral epithelial and cranial neural crest-derived mesenchymal cells give rise to the teeth and periodontium. Teeth are vital organs containing a rich number of blood vessels and nerve fibers within the dental pulp and periodontium. Teeth are composed by unique and specific collagenous (dentin, fibrillar cementum) and non-collagenous (enamel) highly mineralized extracellular matrices. Alveolar bone is another collagenous hard tissue that supports tooth stability and function through its close interaction with the periodontal ligament. Dental hard tissues are often damaged after infection or traumatic injuries that lead to the partial or complete d...
Stem Cell Biology and Regenerative Medicine
The study of stem cell biology is under intensive investigation. Because stem cells have the unique capability to self-renew and differentiate into one or several cell types, they play a critical role in development, tissue homeostasis and regeneration. Stem cells also constitute promising cell candidates for cell and gene therapy. The aim of this book is to provide readers and researchers with timely and accurate knowledge on stem cell biology and regenerative medicine. This book will cover many topics in the field and is based on conferences given by recognized scientists involved in the international master course on stem cell biology at Sorbonne Université in Paris.
Advances in Craniofacial and Dental Materials Through Nanotechnology and Tissue Engineering
Dental and craniofacial treatments are actually based on advances in biomaterials, tissue engineering and nanotechnology sciences. These developments brought considerable improvements on biomaterials commonly used in dental clinics. However, there is still a medical need for innovative techniques and materials for a controllable and efficient regeneration/repair of damaged craniofacial tissues and teeth. The novel biomaterials, imaging techniques, diagnostic and technological tools may offer thrilling perspectives for alternative treatments in dentistry.
Biodental Engineering IV
Since dentistry is a branch of medicine with its own peculiarities and very diverse areas of action, it can be considered as an interdisciplinary field. BIODENTAL ENGINEERING IV contains the full papers presented at the 4th International Conference on Biodental Engineering (BIODENTAL 2016, Vila Nova de Famalicão, Portugal, 21—23 June 2016), and covers the use of new techniques and technologies in dentistry. The contributions provide a comprehensive coverage of the state-of-the art in this area, and addresses the following topics: • Aesthetics • Bioengineering • Biomaterials • Biomechanical disorders • Biomedical devices • Computational bio- imaging and visualization • Comput...
Root Caries: From Prevalence to Therapy
Case reports and clinical trials conducted in various countries show, more and more frequently, a positive correlation between the presence of original teeth and prevalence of root caries in older age. Because this is a global trend, it is likely that the predicted increase in the worldwide elderly population may soon cause a significant increase in the number of people requiring effective means of preventing and treating root surface caries. In response to this development, a team of outstanding contributors has reviewed the most important aspects of root caries. This new volume presents their findings along with discussions of how to deal with this health issue that progressively affects the oral health balance. The chapters in this book are divided in four core parts: Epidemiology, Biological Determinants, Lesion Assessment and Features and Preventive and Operative Therapies. The collection of state-of-the-art articles provides a broad overview and will serve as a reference for clinicians as well as scientists and, hopefully, will encourage new research.
Enamel Research: Mechanisms and Characterization
The rodent incisor is a good model system to study the molecular and cellular events that are involved in enamel biomineralization. Incisors in rodents continuously erupt during their lifespan, thus allowing the study of all stages of enamel synthesis, deposition, mineralization and maturation in the same tissue section. This model system has provided invaluable insight into the specifics of enamel formation as a basis to understand human pathologies such as amelogenesis imperfect. Furthermore, the rodent incisor allows exploration and understanding of some of the most fundamental mechanisms that govern biomineralization. Enamel is the most mineralized, hardest tissue in the body. It is form...
